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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 20562859

Journal: Nature (0028-0836)

Year of Publication: 2010

Title: Network organization of the human autophagy system.

Author List: Behrends C., Sowa ME., Gygi SP., Harper JW.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Experiment (65 interactions)

Accession: EBI-3183386

Name: behrends-2010-1

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
11805837
-
see-also
psi-mi
MI:0102
-
identity
pubmed
11752590
-
method reference
pubmed
10967324
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
wade_harper@hms.harvard.edu
Participants were identified based on results from LTQ linear ion trap LC MS/MS.
Participants were identified based on results from LTQ linear ion trap LC MS/MS.
High-confidence candidate interaction proteins were identified using CompPASS, an automated MS/MS data-processing component, a protein function/annotation component, and an interaction network analysis component adapted to aid in the identification of interacting proteins that are associated with multiple baits in a network. Interactors were scored using the D score which incorporates the uniqueness, the abundance of the interactor (TSC), and the reproducibility of the interaction to assign a score to each protein within each IP (the same protein in two different IPs may have distinct D scores since its TSC and reproducibility could differ). In this way, the highest scores are given to proteins in each IP that are found rarely, found in duplicate runs, and have high TSCs-all characteristics of proteins that would be considered candidate interactors. A global D score threshold (DT) is determined and all raw D scores (DR) are normalized to this value, producing DN scores. For further details, see PMID: 19615732.
imex curation
Only protein-protein interactions
-

Interaction

Accession: EBI-3197899

Name: sqstm1-aamp

Description: -

Type: physical association

Interaction type: physical association
Accession: EBI-1813147

Name: physical association

Description: physical association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0915
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules within the same physical complex. Often identified under conditions which suggest that the molecules are in close proximity but not necessarily in direct contact with each other.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Table S3

Participants (62)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp1234pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp1234pp
1
EBI-307104
 logo
dastyLogo
SQSTM1
ORCA
OSIL

[+3]
Sequestosome-1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Sequestosome-1

Participant: Sequestosome-1

Accession: EBI-3198845

Name: EBI-307104

P
Participant: Sequestosome-1

Participant: Sequestosome-1

Accession: EBI-3198845

Name: EBI-307104

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Sequestosome-1

Participant: Sequestosome-1

Accession: EBI-3198845

Name: EBI-307104

Stoichiometry: 0.0

F
Participant: Sequestosome-1

Participant: Sequestosome-1

Accession: EBI-3198845

Name: EBI-307104

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
n terminal region
  • n-n
  • A
    Feature: EBI-3198847

    Feature: n terminal region

    Accession: EBI-3198847

    Name: n terminal region


    C
    Participant: Sequestosome-1

    Participant: Sequestosome-1

    Accession: EBI-3198845

    Name: EBI-307104

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-1017775
     logo
    dastyLogo
    SAV1
    WW45
    45 kDa WW domain protein
    Protein salvador homolog 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein salvador homolog 1

    Participant: Protein salvador homolog 1

    Accession: EBI-3197941

    Name: EBI-1017775

    P
    Participant: Protein salvador homolog 1

    Participant: Protein salvador homolog 1

    Accession: EBI-3197941

    Name: EBI-1017775

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein salvador homolog 1

    Participant: Protein salvador homolog 1

    Accession: EBI-3197941

    Name: EBI-1017775

    Stoichiometry: 0.0

    F
    Participant: Protein salvador homolog 1

    Participant: Protein salvador homolog 1

    Accession: EBI-3197941

    Name: EBI-1017775

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein salvador homolog 1

    Participant: Protein salvador homolog 1

    Accession: EBI-3197941

    Name: EBI-1017775

    Confidences:

    Type
    Value
    High
    2.92
    0
    p-Value=0 and Normalised Weighted D-Score =2.92

    3
    EBI-295634
     logo
    dastyLogo
    CDC37
    Hsp90 chaperone protein kinase-targeting subunit
    p50Cdc37

    [+1]
    Hsp90 co-chaperone Cdc37
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-3198005

    Name: EBI-295634

    P
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-3198005

    Name: EBI-295634

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-3198005

    Name: EBI-295634

    Stoichiometry: 0.0

    F
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-3198005

    Name: EBI-295634

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-3198005

    Name: EBI-295634

    Confidences:

    Type
    Value
    High
    1.01
    0
    p-Value=0 and Normalised Weighted D-Score =1.01

    4
    EBI-1049768
     logo
    dastyLogo
    Seryl-tRNA(Ser/Sec) synthetase
    SerRSmt
    SARS2

    [+2]
    Serine--tRNA ligase, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine--tRNA ligase, mitochondrial

    Participant: Serine--tRNA ligase, mitochondrial

    Accession: EBI-3198017

    Name: EBI-1049768

    P
    Participant: Serine--tRNA ligase, mitochondrial

    Participant: Serine--tRNA ligase, mitochondrial

    Accession: EBI-3198017

    Name: EBI-1049768

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine--tRNA ligase, mitochondrial

    Participant: Serine--tRNA ligase, mitochondrial

    Accession: EBI-3198017

    Name: EBI-1049768

    Stoichiometry: 0.0

    F
    Participant: Serine--tRNA ligase, mitochondrial

    Participant: Serine--tRNA ligase, mitochondrial

    Accession: EBI-3198017

    Name: EBI-1049768

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine--tRNA ligase, mitochondrial

    Participant: Serine--tRNA ligase, mitochondrial

    Accession: EBI-3198017

    Name: EBI-1049768

    Confidences:

    Type
    Value
    High
    2.06
    p-Value=0 and Normalised Weighted D-Score =2.06
    0

    5
    EBI-395312
     logo
    dastyLogo
    TMLHE
    TMLH
    Epsilon-trimethyllysine 2-oxoglutarate dioxygenase

    [+3]
    Trimethyllysine dioxygenase, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Trimethyllysine dioxygenase, mitochondrial

    Participant: Trimethyllysine dioxygenase, mitochondrial

    Accession: EBI-3198021

    Name: EBI-395312

    P
    Participant: Trimethyllysine dioxygenase, mitochondrial

    Participant: Trimethyllysine dioxygenase, mitochondrial

    Accession: EBI-3198021

    Name: EBI-395312

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Trimethyllysine dioxygenase, mitochondrial

    Participant: Trimethyllysine dioxygenase, mitochondrial

    Accession: EBI-3198021

    Name: EBI-395312

    Stoichiometry: 0.0

    F
    Participant: Trimethyllysine dioxygenase, mitochondrial

    Participant: Trimethyllysine dioxygenase, mitochondrial

    Accession: EBI-3198021

    Name: EBI-395312

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Trimethyllysine dioxygenase, mitochondrial

    Participant: Trimethyllysine dioxygenase, mitochondrial

    Accession: EBI-3198021

    Name: EBI-395312

    Confidences:

    Type
    Value
    High
    3.57
    p-Value=0 and Normalised Weighted D-Score =3.57
    0

    6
    EBI-721385
     logo
    dastyLogo
    MRPS9
    RPMS9
    28S ribosomal protein S9, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 28S ribosomal protein S9, mitochondrial

    Participant: 28S ribosomal protein S9, mitochondrial

    Accession: EBI-3198065

    Name: EBI-721385

    P
    Participant: 28S ribosomal protein S9, mitochondrial

    Participant: 28S ribosomal protein S9, mitochondrial

    Accession: EBI-3198065

    Name: EBI-721385

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 28S ribosomal protein S9, mitochondrial

    Participant: 28S ribosomal protein S9, mitochondrial

    Accession: EBI-3198065

    Name: EBI-721385

    Stoichiometry: 0.0

    F
    Participant: 28S ribosomal protein S9, mitochondrial

    Participant: 28S ribosomal protein S9, mitochondrial

    Accession: EBI-3198065

    Name: EBI-721385

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 28S ribosomal protein S9, mitochondrial

    Participant: 28S ribosomal protein S9, mitochondrial

    Accession: EBI-3198065

    Name: EBI-721385

    Confidences:

    Type
    Value
    High
    1.14
    0
    p-Value=0 and Normalised Weighted D-Score =1.14

    7
    EBI-701927
     logo
    dastyLogo
    p120 catenin
    Cadherin-associated Src substrate
    p120(cas)

    [+2]
    Catenin delta-1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Catenin delta-1

    Participant: Catenin delta-1

    Accession: EBI-3198081

    Name: EBI-701927

    P
    Participant: Catenin delta-1

    Participant: Catenin delta-1

    Accession: EBI-3198081

    Name: EBI-701927

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Catenin delta-1

    Participant: Catenin delta-1

    Accession: EBI-3198081

    Name: EBI-701927

    Stoichiometry: 0.0

    F
    Participant: Catenin delta-1

    Participant: Catenin delta-1

    Accession: EBI-3198081

    Name: EBI-701927

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Catenin delta-1

    Participant: Catenin delta-1

    Accession: EBI-3198081

    Name: EBI-701927

    Confidences:

    Type
    Value
    p-Value=0 and Normalised Weighted D-Score =5.08
    High
    5.08
    0

    8
    EBI-3197846
     logo
    dastyLogo
    ENPP1
    M6S1
    NPPS

    [+5]
    Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Accession: EBI-3198141

    Name: EBI-3197846

    P
    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Accession: EBI-3198141

    Name: EBI-3197846

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Accession: EBI-3198141

    Name: EBI-3197846

    Stoichiometry: 0.0

    F
    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Accession: EBI-3198141

    Name: EBI-3197846

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Participant: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Accession: EBI-3198141

    Name: EBI-3197846

    Confidences:

    Type
    Value
    High
    16.36
    p-Value=0.00000000000128 and Normalised Weighted D-Score =16.36
    0.00000000000128

    9
    EBI-1054873
     logo
    dastyLogo
    GTF3C3
    Transcription factor IIIC subunit gamma
    Transcription factor IIIC 102 kDa subunit
    General transcription factor 3C polypeptide 3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: General transcription factor 3C polypeptide 3

    Participant: General transcription factor 3C polypeptide 3

    Accession: EBI-3198185

    Name: EBI-1054873

    P
    Participant: General transcription factor 3C polypeptide 3

    Participant: General transcription factor 3C polypeptide 3

    Accession: EBI-3198185

    Name: EBI-1054873

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: General transcription factor 3C polypeptide 3

    Participant: General transcription factor 3C polypeptide 3

    Accession: EBI-3198185

    Name: EBI-1054873

    Stoichiometry: 0.0

    F
    Participant: General transcription factor 3C polypeptide 3

    Participant: General transcription factor 3C polypeptide 3

    Accession: EBI-3198185

    Name: EBI-1054873

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: General transcription factor 3C polypeptide 3

    Participant: General transcription factor 3C polypeptide 3

    Accession: EBI-3198185

    Name: EBI-1054873

    Confidences:

    Type
    Value
    High
    5.05
    p-Value=0.00000000565 and Normalised Weighted D-Score =5.05
    0.00000000565

    10
    EBI-367376
     logo
    dastyLogo
    STK4
    MST1
    STE20-like kinase MST1

    [+3]
    Serine/threonine-protein kinase 4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase 4

    Participant: Serine/threonine-protein kinase 4

    Accession: EBI-3198201

    Name: EBI-367376

    P
    Participant: Serine/threonine-protein kinase 4

    Participant: Serine/threonine-protein kinase 4

    Accession: EBI-3198201

    Name: EBI-367376

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase 4

    Participant: Serine/threonine-protein kinase 4

    Accession: EBI-3198201

    Name: EBI-367376

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase 4

    Participant: Serine/threonine-protein kinase 4

    Accession: EBI-3198201

    Name: EBI-367376

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase 4

    Participant: Serine/threonine-protein kinase 4

    Accession: EBI-3198201

    Name: EBI-367376

    Confidences:

    Type
    Value
    p-Value=0 and Normalised Weighted D-Score =2.27
    High
    2.27
    0

    11
    EBI-751001
     logo
    dastyLogo
    Cytosolic inhibitor of Nrf2
    Kelch-like protein 19
    KEAP1

    [+3]
    Kelch-like ECH-associated protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Kelch-like ECH-associated protein 1

    Participant: Kelch-like ECH-associated protein 1

    Accession: EBI-3198213

    Name: EBI-751001

    P
    Participant: Kelch-like ECH-associated protein 1

    Participant: Kelch-like ECH-associated protein 1

    Accession: EBI-3198213

    Name: EBI-751001

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Kelch-like ECH-associated protein 1

    Participant: Kelch-like ECH-associated protein 1

    Accession: EBI-3198213

    Name: EBI-751001

    Stoichiometry: 0.0

    F
    Participant: Kelch-like ECH-associated protein 1

    Participant: Kelch-like ECH-associated protein 1

    Accession: EBI-3198213

    Name: EBI-751001

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Kelch-like ECH-associated protein 1

    Participant: Kelch-like ECH-associated protein 1

    Accession: EBI-3198213

    Name: EBI-751001

    Confidences:

    Type
    Value
    High
    2.26
    p-Value=0 and Normalised Weighted D-Score =2.26
    0

    12
    EBI-2967294
     logo
    dastyLogo
    ASPH
    Aspartate beta-hydroxylase
    Peptide-aspartate beta-dioxygenase

    [+1]
    Aspartyl/asparaginyl beta-hydroxylase
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Accession: EBI-3198249

    Name: EBI-2967294

    P
    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Accession: EBI-3198249

    Name: EBI-2967294

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Accession: EBI-3198249

    Name: EBI-2967294

    Stoichiometry: 0.0

    F
    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Accession: EBI-3198249

    Name: EBI-2967294

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Participant: Aspartyl/asparaginyl beta-hydroxylase

    Accession: EBI-3198249

    Name: EBI-2967294

    Confidences:

    Type
    Value
    High
    4.86
    0
    p-Value=0 and Normalised Weighted D-Score =4.86

    13
    EBI-2963275
     logo
    dastyLogo
    COX11
    Cytochrome c oxidase assembly protein COX11, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Accession: EBI-3198261

    Name: EBI-2963275

    P
    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Accession: EBI-3198261

    Name: EBI-2963275

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Accession: EBI-3198261

    Name: EBI-2963275

    Stoichiometry: 0.0

    F
    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Accession: EBI-3198261

    Name: EBI-2963275

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Participant: Cytochrome c oxidase assembly protein COX11, mitochondrial

    Accession: EBI-3198261

    Name: EBI-2963275

    Confidences:

    Type
    Value
    High
    1.09
    p-Value=0 and Normalised Weighted D-Score =1.09
    0

    14
    EBI-3050469
     logo
    dastyLogo
    GPC4
    K-glypican
    UNQ474/PRO937
    Glypican-4
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Glypican-4

    Participant: Glypican-4

    Accession: EBI-3198325

    Name: EBI-3050469

    P
    Participant: Glypican-4

    Participant: Glypican-4

    Accession: EBI-3198325

    Name: EBI-3050469

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Glypican-4

    Participant: Glypican-4

    Accession: EBI-3198325

    Name: EBI-3050469

    Stoichiometry: 0.0

    F
    Participant: Glypican-4

    Participant: Glypican-4

    Accession: EBI-3198325

    Name: EBI-3050469

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Glypican-4

    Participant: Glypican-4

    Accession: EBI-3198325

    Name: EBI-3050469

    Confidences:

    Type
    Value
    p-Value=0 and Normalised Weighted D-Score =5.83
    High
    5.83
    0

    15
    EBI-297954
     logo
    dastyLogo
    EPPK1
    EPIPL
    450 kDa epidermal antigen
    Epiplakin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Epiplakin

    Participant: Epiplakin

    Accession: EBI-3198349

    Name: EBI-297954

    P
    Participant: Epiplakin

    Participant: Epiplakin

    Accession: EBI-3198349

    Name: EBI-297954

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Epiplakin

    Participant: Epiplakin

    Accession: EBI-3198349

    Name: EBI-297954

    Stoichiometry: 0.0

    F
    Participant: Epiplakin

    Participant: Epiplakin

    Accession: EBI-3198349

    Name: EBI-297954

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Epiplakin

    Participant: Epiplakin

    Accession: EBI-3198349

    Name: EBI-297954

    Confidences:

    Type
    Value
    p-Value=0 and Normalised Weighted D-Score =2.38
    High
    2.38
    0

    16
    EBI-2562690
     logo
    dastyLogo
    C9orf81
    CEP78
    Centrosomal protein of 78 kDa
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Centrosomal protein of 78 kDa

    Participant: Centrosomal protein of 78 kDa

    Accession: EBI-3198365

    Name: EBI-2562690

    P
    Participant: Centrosomal protein of 78 kDa

    Participant: Centrosomal protein of 78 kDa

    Accession: EBI-3198365

    Name: EBI-2562690

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Centrosomal protein of 78 kDa

    Participant: Centrosomal protein of 78 kDa

    Accession: EBI-3198365

    Name: EBI-2562690

    Stoichiometry: 0.0

    F
    Participant: Centrosomal protein of 78 kDa

    Participant: Centrosomal protein of 78 kDa

    Accession: EBI-3198365

    Name: EBI-2562690

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Centrosomal protein of 78 kDa

    Participant: Centrosomal protein of 78 kDa

    Accession: EBI-3198365

    Name: EBI-2562690

    Confidences:

    Type
    Value
    High
    17.49
    0
    p-Value=0 and Normalised Weighted D-Score =17.49

    17
    EBI-354007
     logo
    dastyLogo
    ANXA1
    ANX1
    LPC1

    [+8]
    Annexin A1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Annexin A1

    Participant: Annexin A1

    Accession: EBI-3198385

    Name: EBI-354007

    P
    Participant: Annexin A1

    Participant: Annexin A1

    Accession: EBI-3198385

    Name: EBI-354007

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Annexin A1

    Participant: Annexin A1

    Accession: EBI-3198385

    Name: EBI-354007

    Stoichiometry: 0.0

    F
    Participant: Annexin A1

    Participant: Annexin A1

    Accession: EBI-3198385

    Name: EBI-354007

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Annexin A1

    Participant: Annexin A1

    Accession: EBI-3198385

    Name: EBI-354007

    Confidences:

    Type
    Value
    High
    2.69
    0
    p-Value=0 and Normalised Weighted D-Score =2.69

    18
    EBI-974488
     logo
    dastyLogo
    CHEK1
    CHK1
    CHK1 checkpoint homolog

    [+2]
    Serine/threonine-protein kinase Chk1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase Chk1

    Participant: Serine/threonine-protein kinase Chk1

    Accession: EBI-3198393

    Name: EBI-974488

    P
    Participant: Serine/threonine-protein kinase Chk1

    Participant: Serine/threonine-protein kinase Chk1

    Accession: EBI-3198393

    Name: EBI-974488

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase Chk1

    Participant: Serine/threonine-protein kinase Chk1

    Accession: EBI-3198393

    Name: EBI-974488

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase Chk1

    Participant: Serine/threonine-protein kinase Chk1

    Accession: EBI-3198393

    Name: EBI-974488

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase Chk1

    Participant: Serine/threonine-protein kinase Chk1

    Accession: EBI-3198393

    Name: EBI-974488

    Confidences:

    Type
    Value
    p-Value=0 and Normalised Weighted D-Score =1.55
    High
    1.55
    0

    19
    EBI-297903
     logo
    dastyLogo
    PLEC
    Hemidesmosomal protein 1
    PLEC1

    [+1]
    Plectin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Plectin

    Participant: Plectin

    Accession: EBI-3198497

    Name: EBI-297903

    P
    Participant: Plectin

    Participant: Plectin

    Accession: EBI-3198497

    Name: EBI-297903

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Plectin

    Participant: Plectin

    Accession: EBI-3198497

    Name: EBI-297903

    Stoichiometry: 0.0

    F
    Participant: Plectin

    Participant: Plectin

    Accession: EBI-3198497

    Name: EBI-297903

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Plectin

    Participant: Plectin

    Accession: EBI-3198497

    Name: EBI-297903

    Confidences:

    Type
    Value
    High
    2.06
    p-Value=0 and Normalised Weighted D-Score =2.06
    0

    20
    EBI-307133
     logo
    dastyLogo
    GBAS
    NIPSNAP2
    Glioblastoma-amplified sequence
    Protein NipSnap homolog 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein NipSnap homolog 2

    Participant: Protein NipSnap homolog 2

    Accession: EBI-3198541

    Name: EBI-307133

    P
    Participant: Protein NipSnap homolog 2

    Participant: Protein NipSnap homolog 2

    Accession: EBI-3198541

    Name: EBI-307133

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein NipSnap homolog 2

    Participant: Protein NipSnap homolog 2

    Accession: EBI-3198541

    Name: EBI-307133

    Stoichiometry: 0.0

    F
    Participant: Protein NipSnap homolog 2

    Participant: Protein NipSnap homolog 2

    Accession: EBI-3198541

    Name: EBI-307133

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein NipSnap homolog 2

    Participant: Protein NipSnap homolog 2

    Accession: EBI-3198541

    Name: EBI-307133

    Confidences:

    Type
    Value
    High
    6.04
    p-Value=0 and Normalised Weighted D-Score =6.04
    0


    Graphical Representation of Experimental Features