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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 19380743

Journal: Proc Natl Acad Sci U S A.

Year of Publication: 2009

Title: Charting the molecular network of the drug target Bcr-Abl

Author List: Marc Brehme, Oliver Hantschel, Jacques Colinge, Ines Kaupe, Melanie Planyavsky, Thomas K�cher, Karl Mechtler, Keiryn L. Bennett, and Giulio Superti-Furga

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Cancer - Interactions investigated in the context of cancer
Synapse - Interactions of proteins with an established role in the presynapse.
Apoptosis - Interactions involving proteins with a function related to apoptosis

Experiment (9 interactions)

Accession: EBI-2614937

Name: brehme-2009-2

Host organism: Homo sapiens myeloid leukemia cells.

Organism: Homo sapiens myeloid leukemia cells.

Accession: EBI-307659

Name: human-k_562

Description: Homo sapiens myeloid leukemia cells.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: tap

Interaction detection method: tap
Accession: EBI-933908

Name: tap

Description: tandem affinity purification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0676
-
identity
pubmed
11403571
-
primary-reference


Annotations:
Topic
Text
definition
Tandem affinity purification allows rapid purification under native conditions of complexes, even when expressed at their natural level. Prior knowledge of complex composition or function is not required. The TAP method requires fusion of the a multiple tag, either N- or C-terminally, to the target (or bait) protein of interest. The multiple tag allows two steps purification steps ensuring a highly selective complex purification.


Participant Identification Method: sequence tag

Participant identification method: sequence tag
Accession: EBI-81

Name: sequence tag

Description: sequence tag identification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
11805837
-
see-also
psi-mi
MI:0102
-
identity
pubmed
10967324
-
method reference
pubmed
11752590
-
primary-reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by combining mass measurement and short amino acid sequence information obtained by tandem mass spectrometry. This information is then used to automatically find the best match in a sequence database. A mixture of peptides derived from a protease digestion is analysed by nanoelectrospray LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometer or nanoESI MS/MS) mass spectrometry. Electrospray mass spectrometry cannot be applied to dilute samples and is affected by high salt. As a consequence peptides, normally extracted from acrylamide gels by in situ proteolysis, are desalted and concentrated on a microcolumn followed by elution into a capillary used for nanoelectrospray tandem mass spectrometry. A first mass spectrum (Normal mass spectrum or Q1 mass spectrum) gives information about the masses of all the peptides. Peptides observed in the normal mass spectrum are isolated in turn and dissociated into fragments by collision with gas molecules within the mass spectrometer. Some of the fragments obtained from a peptide constitute a nested set, differing by one amino acid, and the mass difference between them allows assignment of a partial sequence. The masses of the fragments define the position of the partial sequence in the peptide. Together with the cleavage specificity of the protease used to cleave the protein, and mass information such sequence tag provides much higher search specificity to match the a database entry. The procedure is repeated with several peptides from the digest, resulting in multiple identifications of the same protein or identification of several proteins from the peptide mixture. Unknown proteins can easily be identified by using the high specificity of the peptide sequence tag for searches in most sequence databases including EST or genome databases.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
gsuperti@cemm.oeaw.ac.at
The UniProtKB IDs of the interactors were deduced from the IPI number in the supplementary file 1. and 3
Only protein-protein interactions
-
imex curation
Specific monoclonal antibody Abl 24-21 against the Abl F-actin binding site of Bcr-Abl and c-Abl. The antibody binds to residues Q1094, Q1095 and M1096 of the Abl F-actin binding site which are not involved in F-actin binding or any other known protein-protein interaction.
The Abl antibody can bind the FABD-C domain of both Bcr-Abl and c-Abl.

Interaction

Accession: EBI-2615019

Name: shc1-ap2a1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Fig. 2, 3 and Supplementary table 5.
The IPI numbers IPI00305469, IPI00793515 and IPI00514550 for respectively crk, csk and dnm2 were not pointing on existing UniProtKB/Swiss-Prot entries for these proteins. The UniProtKB/Swiss-Prot ID was deduced from the gene name given by the author and confirmed by a blast.
P29353 transformation

Participants (29)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12pp
1
EBI-78835
 logo
SHC1
SHC-transforming protein 3
SHC-transforming protein A

[+3]
SHC-transforming protein 1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
No records found.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: SHC-transforming protein 1

Participant: SHC-transforming protein 1

Accession: EBI-2615025

Name: EBI-78835

P
Participant: SHC-transforming protein 1

Participant: SHC-transforming protein 1

Accession: EBI-2615025

Name: EBI-78835

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: SHC-transforming protein 1

Participant: SHC-transforming protein 1

Accession: EBI-2615025

Name: EBI-78835

Stoichiometry: 0.0

F
Participant: SHC-transforming protein 1

Participant: SHC-transforming protein 1

Accession: EBI-2615025

Name: EBI-78835

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
n-terminal
  • n-n
  • A
    Feature: EBI-2615026

    Feature: n-terminal

    Accession: EBI-2615026

    Name: n-terminal


    C
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615025

    Name: EBI-78835

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-351275
     logo
    PPP1R9B
    PPP1R6
    Protein phosphatase 1 regulatory subunit 9B

    [+2]
    Neurabin-2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Neurabin-2

    Participant: Neurabin-2

    Accession: EBI-2615023

    Name: EBI-351275

    P
    Participant: Neurabin-2

    Participant: Neurabin-2

    Accession: EBI-2615023

    Name: EBI-351275

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Neurabin-2

    Participant: Neurabin-2

    Accession: EBI-2615023

    Name: EBI-351275

    Stoichiometry: 0.0

    F
    Participant: Neurabin-2

    Participant: Neurabin-2

    Accession: EBI-2615023

    Name: EBI-351275

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Neurabin-2

    Participant: Neurabin-2

    Accession: EBI-2615023

    Name: EBI-351275

    Confidences:

    Type
    Value
    No records found.

    3
    EBI-518228
     logo
    CBL
    RNF55
    CBL2

    [+4]
    E3 ubiquitin-protein ligase CBL
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 ubiquitin-protein ligase CBL

    Participant: E3 ubiquitin-protein ligase CBL

    Accession: EBI-2615024

    Name: EBI-518228

    P
    Participant: E3 ubiquitin-protein ligase CBL

    Participant: E3 ubiquitin-protein ligase CBL

    Accession: EBI-2615024

    Name: EBI-518228

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 ubiquitin-protein ligase CBL

    Participant: E3 ubiquitin-protein ligase CBL

    Accession: EBI-2615024

    Name: EBI-518228

    Stoichiometry: 0.0

    F
    Participant: E3 ubiquitin-protein ligase CBL

    Participant: E3 ubiquitin-protein ligase CBL

    Accession: EBI-2615024

    Name: EBI-518228

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 ubiquitin-protein ligase CBL

    Participant: E3 ubiquitin-protein ligase CBL

    Accession: EBI-2615024

    Name: EBI-518228

    Confidences:

    Type
    Value
    No records found.

    4
    EBI-375617
     logo
    SPTA1
    SPTA
    Erythroid alpha-spectrin
    Spectrin alpha chain, erythrocytic 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Spectrin alpha chain, erythrocytic 1

    Participant: Spectrin alpha chain, erythrocytic 1

    Accession: EBI-2615028

    Name: EBI-375617

    P
    Participant: Spectrin alpha chain, erythrocytic 1

    Participant: Spectrin alpha chain, erythrocytic 1

    Accession: EBI-2615028

    Name: EBI-375617

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Spectrin alpha chain, erythrocytic 1

    Participant: Spectrin alpha chain, erythrocytic 1

    Accession: EBI-2615028

    Name: EBI-375617

    Stoichiometry: 0.0

    F
    Participant: Spectrin alpha chain, erythrocytic 1

    Participant: Spectrin alpha chain, erythrocytic 1

    Accession: EBI-2615028

    Name: EBI-375617

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Spectrin alpha chain, erythrocytic 1

    Participant: Spectrin alpha chain, erythrocytic 1

    Accession: EBI-2615028

    Name: EBI-375617

    Confidences:

    Type
    Value
    No records found.

    5
    EBI-346547
     logo
    DNM2
    DYN2
    Dynamin-2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dynamin-2

    Participant: Dynamin-2

    Accession: EBI-2615029

    Name: EBI-346547

    P
    Participant: Dynamin-2

    Participant: Dynamin-2

    Accession: EBI-2615029

    Name: EBI-346547

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dynamin-2

    Participant: Dynamin-2

    Accession: EBI-2615029

    Name: EBI-346547

    Stoichiometry: 0.0

    F
    Participant: Dynamin-2

    Participant: Dynamin-2

    Accession: EBI-2615029

    Name: EBI-346547

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dynamin-2

    Participant: Dynamin-2

    Accession: EBI-2615029

    Name: EBI-346547

    Confidences:

    Type
    Value
    No records found.

    6
    EBI-350423
     logo
    MYO1C
    Myosin I beta
    Unconventional myosin-Ic
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Unconventional myosin-Ic

    Participant: Unconventional myosin-Ic

    Accession: EBI-2615030

    Name: EBI-350423

    P
    Participant: Unconventional myosin-Ic

    Participant: Unconventional myosin-Ic

    Accession: EBI-2615030

    Name: EBI-350423

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Unconventional myosin-Ic

    Participant: Unconventional myosin-Ic

    Accession: EBI-2615030

    Name: EBI-350423

    Stoichiometry: 0.0

    F
    Participant: Unconventional myosin-Ic

    Participant: Unconventional myosin-Ic

    Accession: EBI-2615030

    Name: EBI-350423

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Unconventional myosin-Ic

    Participant: Unconventional myosin-Ic

    Accession: EBI-2615030

    Name: EBI-350423

    Confidences:

    Type
    Value
    No records found.

    7
    EBI-1642835
     logo
    AP2A2
    Adaptor-related protein complex 2 subunit alpha-2
    Huntingtin-interacting protein 9

    [+13]
    AP-2 complex subunit alpha-2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: AP-2 complex subunit alpha-2

    Participant: AP-2 complex subunit alpha-2

    Accession: EBI-2615031

    Name: EBI-1642835

    P
    Participant: AP-2 complex subunit alpha-2

    Participant: AP-2 complex subunit alpha-2

    Accession: EBI-2615031

    Name: EBI-1642835

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: AP-2 complex subunit alpha-2

    Participant: AP-2 complex subunit alpha-2

    Accession: EBI-2615031

    Name: EBI-1642835

    Stoichiometry: 0.0

    F
    Participant: AP-2 complex subunit alpha-2

    Participant: AP-2 complex subunit alpha-2

    Accession: EBI-2615031

    Name: EBI-1642835

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: AP-2 complex subunit alpha-2

    Participant: AP-2 complex subunit alpha-2

    Accession: EBI-2615031

    Name: EBI-1642835

    Confidences:

    Type
    Value
    No records found.

    8
    EBI-2266035
     logo
    PTPN12
    PTP-PEST
    Protein-tyrosine phosphatase G1
    Tyrosine-protein phosphatase non-receptor type 12
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Accession: EBI-2615032

    Name: EBI-2266035

    P
    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Accession: EBI-2615032

    Name: EBI-2266035

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Accession: EBI-2615032

    Name: EBI-2266035

    Stoichiometry: 0.0

    F
    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Accession: EBI-2615032

    Name: EBI-2266035

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Participant: Tyrosine-protein phosphatase non-receptor type 12

    Accession: EBI-2615032

    Name: EBI-2266035

    Confidences:

    Type
    Value
    No records found.

    9
    EBI-2609610
     logo
    PSTPIP2
    Proline-serine-threonine phosphatase-interacting protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Accession: EBI-2615033

    Name: EBI-2609610

    P
    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Accession: EBI-2615033

    Name: EBI-2609610

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Accession: EBI-2615033

    Name: EBI-2609610

    Stoichiometry: 0.0

    F
    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Accession: EBI-2615033

    Name: EBI-2609610

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Participant: Proline-serine-threonine phosphatase-interacting protein 2

    Accession: EBI-2615033

    Name: EBI-2609610

    Confidences:

    Type
    Value
    No records found.

    10
    EBI-886
     logo
    CRK
    p38
    Proto-oncogene c-Crk
    Adapter molecule crk
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Adapter molecule crk

    Participant: Adapter molecule crk

    Accession: EBI-2615034

    Name: EBI-886

    P
    Participant: Adapter molecule crk

    Participant: Adapter molecule crk

    Accession: EBI-2615034

    Name: EBI-886

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Adapter molecule crk

    Participant: Adapter molecule crk

    Accession: EBI-2615034

    Name: EBI-886

    Stoichiometry: 0.0

    F
    Participant: Adapter molecule crk

    Participant: Adapter molecule crk

    Accession: EBI-2615034

    Name: EBI-886

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Adapter molecule crk

    Participant: Adapter molecule crk

    Accession: EBI-2615034

    Name: EBI-886

    Confidences:

    Type
    Value
    No records found.

    11
    EBI-297487
     logo
    SOS1
    Son of sevenless homolog 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Son of sevenless homolog 1

    Participant: Son of sevenless homolog 1

    Accession: EBI-2615035

    Name: EBI-297487

    P
    Participant: Son of sevenless homolog 1

    Participant: Son of sevenless homolog 1

    Accession: EBI-2615035

    Name: EBI-297487

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Son of sevenless homolog 1

    Participant: Son of sevenless homolog 1

    Accession: EBI-2615035

    Name: EBI-297487

    Stoichiometry: 0.0

    F
    Participant: Son of sevenless homolog 1

    Participant: Son of sevenless homolog 1

    Accession: EBI-2615035

    Name: EBI-297487

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Son of sevenless homolog 1

    Participant: Son of sevenless homolog 1

    Accession: EBI-2615035

    Name: EBI-297487

    Confidences:

    Type
    Value
    No records found.

    12
    EBI-1380492
     logo
    UBASH3B
    Tyrosine-protein phosphatase STS1/TULA2
    T-cell ubiquitin ligand 2

    [+4]
    Ubiquitin-associated and SH3 domain-containing protein B
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Accession: EBI-2615036

    Name: EBI-1380492

    P
    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Accession: EBI-2615036

    Name: EBI-1380492

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Accession: EBI-2615036

    Name: EBI-1380492

    Stoichiometry: 0.0

    F
    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Accession: EBI-2615036

    Name: EBI-1380492

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Participant: Ubiquitin-associated and SH3 domain-containing protein B

    Accession: EBI-2615036

    Name: EBI-1380492

    Confidences:

    Type
    Value
    No records found.

    13
    EBI-2322142
     logo
    USP9Y
    Ubiquitin thioesterase FAF-Y
    Ubiquitin-specific protease 9, Y chromosome

    [+4]
    Probable ubiquitin carboxyl-terminal hydrolase FAF-Y
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Accession: EBI-2615037

    Name: EBI-2322142

    P
    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Accession: EBI-2615037

    Name: EBI-2322142

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Accession: EBI-2615037

    Name: EBI-2322142

    Stoichiometry: 0.0

    F
    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Accession: EBI-2615037

    Name: EBI-2322142

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Participant: Probable ubiquitin carboxyl-terminal hydrolase FAF-Y

    Accession: EBI-2615037

    Name: EBI-2322142

    Confidences:

    Type
    Value
    No records found.

    14
    EBI-347559
     logo
    IKBKAP
    ELP1
    IKAP

    [+2]
    Elongator complex protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Elongator complex protein 1

    Participant: Elongator complex protein 1

    Accession: EBI-2615038

    Name: EBI-347559

    P
    Participant: Elongator complex protein 1

    Participant: Elongator complex protein 1

    Accession: EBI-2615038

    Name: EBI-347559

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Elongator complex protein 1

    Participant: Elongator complex protein 1

    Accession: EBI-2615038

    Name: EBI-347559

    Stoichiometry: 0.0

    F
    Participant: Elongator complex protein 1

    Participant: Elongator complex protein 1

    Accession: EBI-2615038

    Name: EBI-347559

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Elongator complex protein 1

    Participant: Elongator complex protein 1

    Accession: EBI-2615038

    Name: EBI-347559

    Confidences:

    Type
    Value
    No records found.

    15
    EBI-352957
     logo
    DNAJA2
    Renal carcinoma antigen NY-REN-14
    Dnj3

    [+4]
    DnaJ homolog subfamily A member 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: DnaJ homolog subfamily A member 2

    Participant: DnaJ homolog subfamily A member 2

    Accession: EBI-2615039

    Name: EBI-352957

    P
    Participant: DnaJ homolog subfamily A member 2

    Participant: DnaJ homolog subfamily A member 2

    Accession: EBI-2615039

    Name: EBI-352957

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: DnaJ homolog subfamily A member 2

    Participant: DnaJ homolog subfamily A member 2

    Accession: EBI-2615039

    Name: EBI-352957

    Stoichiometry: 0.0

    F
    Participant: DnaJ homolog subfamily A member 2

    Participant: DnaJ homolog subfamily A member 2

    Accession: EBI-2615039

    Name: EBI-352957

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: DnaJ homolog subfamily A member 2

    Participant: DnaJ homolog subfamily A member 2

    Accession: EBI-2615039

    Name: EBI-352957

    Confidences:

    Type
    Value
    No records found.

    16
    EBI-357515
     logo
    SEC16A
    SEC16 homolog A
    SEC16L

    [+2]
    Protein transport protein Sec16A
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein transport protein Sec16A

    Participant: Protein transport protein Sec16A

    Accession: EBI-2615040

    Name: EBI-357515

    P
    Participant: Protein transport protein Sec16A

    Participant: Protein transport protein Sec16A

    Accession: EBI-2615040

    Name: EBI-357515

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein transport protein Sec16A

    Participant: Protein transport protein Sec16A

    Accession: EBI-2615040

    Name: EBI-357515

    Stoichiometry: 0.0

    F
    Participant: Protein transport protein Sec16A

    Participant: Protein transport protein Sec16A

    Accession: EBI-2615040

    Name: EBI-357515

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein transport protein Sec16A

    Participant: Protein transport protein Sec16A

    Accession: EBI-2615040

    Name: EBI-357515

    Confidences:

    Type
    Value
    No records found.

    17
    EBI-79464
     logo
    PIK3R1
    Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
    GRB1
    Phosphatidylinositol 3-kinase regulatory subunit alpha
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Accession: EBI-2615041

    Name: EBI-79464

    P
    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Accession: EBI-2615041

    Name: EBI-79464

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Accession: EBI-2615041

    Name: EBI-79464

    Stoichiometry: 0.0

    F
    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Accession: EBI-2615041

    Name: EBI-79464

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Participant: Phosphatidylinositol 3-kinase regulatory subunit alpha

    Accession: EBI-2615041

    Name: EBI-79464

    Confidences:

    Type
    Value
    No records found.

    18
    EBI-1380630
     logo
    CSK
    Protein-tyrosine kinase CYL
    C-Src kinase
    Tyrosine-protein kinase CSK
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Tyrosine-protein kinase CSK

    Participant: Tyrosine-protein kinase CSK

    Accession: EBI-2615042

    Name: EBI-1380630

    P
    Participant: Tyrosine-protein kinase CSK

    Participant: Tyrosine-protein kinase CSK

    Accession: EBI-2615042

    Name: EBI-1380630

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Tyrosine-protein kinase CSK

    Participant: Tyrosine-protein kinase CSK

    Accession: EBI-2615042

    Name: EBI-1380630

    Stoichiometry: 0.0

    F
    Participant: Tyrosine-protein kinase CSK

    Participant: Tyrosine-protein kinase CSK

    Accession: EBI-2615042

    Name: EBI-1380630

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Tyrosine-protein kinase CSK

    Participant: Tyrosine-protein kinase CSK

    Accession: EBI-2615042

    Name: EBI-1380630

    Confidences:

    Type
    Value
    No records found.

    19
    EBI-355504
     logo
    CAD
    CAD protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: CAD protein

    Participant: CAD protein

    Accession: EBI-2615043

    Name: EBI-355504

    P
    Participant: CAD protein

    Participant: CAD protein

    Accession: EBI-2615043

    Name: EBI-355504

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: CAD protein

    Participant: CAD protein

    Accession: EBI-2615043

    Name: EBI-355504

    Stoichiometry: 0.0

    F
    Participant: CAD protein

    Participant: CAD protein

    Accession: EBI-2615043

    Name: EBI-355504

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: CAD protein

    Participant: CAD protein

    Accession: EBI-2615043

    Name: EBI-355504

    Confidences:

    Type
    Value
    No records found.

    20
    EBI-78835
     logo
    SHC1
    SHC-transforming protein 3
    SHC-transforming protein A

    [+3]
    SHC-transforming protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615044

    Name: EBI-78835

    P
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615044

    Name: EBI-78835

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615044

    Name: EBI-78835

    Stoichiometry: 0.0

    F
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615044

    Name: EBI-78835

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: SHC-transforming protein 1

    Participant: SHC-transforming protein 1

    Accession: EBI-2615044

    Name: EBI-78835

    Confidences:

    Type
    Value
    No records found.


    Graphical Representation of Experimental Features