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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 17979178

Journal: Proteomics (1615-9853)

Year of Publication: 2007

Title: A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.

Author List: Gloeckner CJ., Boldt K., Schumacher A., Roepman R., Ueffing M.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Synapse - Interactions of proteins with an established role in the presynapse.
Apoptosis - Interactions involving proteins with a function related to apoptosis

Experiment (3 interactions)

Accession: EBI-1643967

Name: gloeckner-2007-3

Host organism: Homo sapiens transformed primary embryonal kidney cells

Organism: Homo sapiens transformed primary embryonal kidney cells

Accession: EBI-307628

Name: human-293

Description: Homo sapiens transformed primary embryonal kidney cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
human
-

Interaction Detection Method: tap

Interaction detection method: tap
Accession: EBI-933908

Name: tap

Description: tandem affinity purification

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0676
-
identity
pubmed
11403571
-
primary-reference


Annotations:
Topic
Text
definition
Tandem affinity purification allows rapid purification under native conditions of complexes, even when expressed at their natural level. Prior knowledge of complex composition or function is not required. The TAP method requires fusion of the a multiple tag, either N- or C-terminally, to the target (or bait) protein of interest. The multiple tag allows two steps purification steps ensuring a highly selective complex purification.


Participant Identification Method: ms participant

Participant identification method: ms participant
Accession: EBI-608794

Name: ms participant

Description: Identification by mass spectrometry

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0427
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
identification by mass spectrometry.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
marius.ueffing@gsf.de
The authors used a modified TAP tagging protocol. The TAP tag consisted of the Strep tag (WSHPQFEK) and a single FLAG tag. Unlike conventional TAP tagging constructs the TEV cleavage site was ommited.
In this experiment purified proteins were sperated using 4-12% NuPAGE gradient gels (Invitrogen), stained and excised from the gel prior to Mass Spectrophotometric based identification.
Only protein-protein interactions
-
9
imex curation

Interaction

Accession: EBI-1643985

Name: braf-ywhae-s4-1

Description: Proteins interacting with BRAF

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Table S1

Participants (17)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
1
EBI-365980
 logo
BRAF
BRAF1
RAFB1

[+3]
Serine/threonine-protein kinase B-raf
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
No records found.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Serine/threonine-protein kinase B-raf

Participant: Serine/threonine-protein kinase B-raf

Accession: EBI-1643991

Name: EBI-365980

P
Participant: Serine/threonine-protein kinase B-raf

Participant: Serine/threonine-protein kinase B-raf

Accession: EBI-1643991

Name: EBI-365980

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Serine/threonine-protein kinase B-raf

Participant: Serine/threonine-protein kinase B-raf

Accession: EBI-1643991

Name: EBI-365980

Stoichiometry: 0.0

F
Participant: Serine/threonine-protein kinase B-raf

Participant: Serine/threonine-protein kinase B-raf

Accession: EBI-1643991

Name: EBI-365980

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
c-terminal
  • c-c
  • A
    Feature: EBI-1643992

    Feature: c-terminal

    Accession: EBI-1643992

    Name: c-terminal

    c-terminal
  • c-c
  • A
    Feature: EBI-1643994

    Feature: c-terminal

    Accession: EBI-1643994

    Name: c-terminal


    C
    Participant: Serine/threonine-protein kinase B-raf

    Participant: Serine/threonine-protein kinase B-raf

    Accession: EBI-1643991

    Name: EBI-365980

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-354932
     logo
    HSPA9
    GRP75
    HSPA9B

    [+5]
    Stress-70 protein, mitochondrial
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Stress-70 protein, mitochondrial

    Participant: Stress-70 protein, mitochondrial

    Accession: EBI-1643987

    Name: EBI-354932

    P
    Participant: Stress-70 protein, mitochondrial

    Participant: Stress-70 protein, mitochondrial

    Accession: EBI-1643987

    Name: EBI-354932

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Stress-70 protein, mitochondrial

    Participant: Stress-70 protein, mitochondrial

    Accession: EBI-1643987

    Name: EBI-354932

    Stoichiometry: 0.0

    F
    Participant: Stress-70 protein, mitochondrial

    Participant: Stress-70 protein, mitochondrial

    Accession: EBI-1643987

    Name: EBI-354932

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Stress-70 protein, mitochondrial

    Participant: Stress-70 protein, mitochondrial

    Accession: EBI-1643987

    Name: EBI-354932

    Confidences:

    Type
    Value
    No records found.

    3
    EBI-1056930
     logo
    MAP2K2
    MEK2
    MKK2

    [+3]
    Dual specificity mitogen-activated protein kinase kinase 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Accession: EBI-1643988

    Name: EBI-1056930

    P
    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Accession: EBI-1643988

    Name: EBI-1056930

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Accession: EBI-1643988

    Name: EBI-1056930

    Stoichiometry: 0.0

    F
    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Accession: EBI-1643988

    Name: EBI-1056930

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Participant: Dual specificity mitogen-activated protein kinase kinase 2

    Accession: EBI-1643988

    Name: EBI-1056930

    Confidences:

    Type
    Value
    No records found.

    4
    EBI-629985
     logo
    HSPA1A
    HSPA1
    HSPA1B

    [+2]
    Heat shock 70 kDa protein 1A/1B
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Heat shock 70 kDa protein 1A/1B

    Participant: Heat shock 70 kDa protein 1A/1B

    Accession: EBI-1643989

    Name: EBI-629985

    P
    Participant: Heat shock 70 kDa protein 1A/1B

    Participant: Heat shock 70 kDa protein 1A/1B

    Accession: EBI-1643989

    Name: EBI-629985

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Heat shock 70 kDa protein 1A/1B

    Participant: Heat shock 70 kDa protein 1A/1B

    Accession: EBI-1643989

    Name: EBI-629985

    Stoichiometry: 0.0

    F
    Participant: Heat shock 70 kDa protein 1A/1B

    Participant: Heat shock 70 kDa protein 1A/1B

    Accession: EBI-1643989

    Name: EBI-629985

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Heat shock 70 kDa protein 1A/1B

    Participant: Heat shock 70 kDa protein 1A/1B

    Accession: EBI-1643989

    Name: EBI-629985

    Confidences:

    Type
    Value
    No records found.

    5
    EBI-352572
     logo
    HSP90AB1
    HSP90B
    HSPC2

    [+2]
    Heat shock protein HSP 90-beta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Heat shock protein HSP 90-beta

    Participant: Heat shock protein HSP 90-beta

    Accession: EBI-1643990

    Name: EBI-352572

    P
    Participant: Heat shock protein HSP 90-beta

    Participant: Heat shock protein HSP 90-beta

    Accession: EBI-1643990

    Name: EBI-352572

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Heat shock protein HSP 90-beta

    Participant: Heat shock protein HSP 90-beta

    Accession: EBI-1643990

    Name: EBI-352572

    Stoichiometry: 0.0

    F
    Participant: Heat shock protein HSP 90-beta

    Participant: Heat shock protein HSP 90-beta

    Accession: EBI-1643990

    Name: EBI-352572

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Heat shock protein HSP 90-beta

    Participant: Heat shock protein HSP 90-beta

    Accession: EBI-1643990

    Name: EBI-352572

    Confidences:

    Type
    Value
    No records found.

    6
    EBI-492564
     logo
    ERK activator kinase 1
    MAPK/ERK kinase 1
    MAP2K1

    [+2]
    Dual specificity mitogen-activated protein kinase kinase 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Accession: EBI-1643996

    Name: EBI-492564

    P
    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Accession: EBI-1643996

    Name: EBI-492564

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Accession: EBI-1643996

    Name: EBI-492564

    Stoichiometry: 0.0

    F
    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Accession: EBI-1643996

    Name: EBI-492564

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Participant: Dual specificity mitogen-activated protein kinase kinase 1

    Accession: EBI-1643996

    Name: EBI-492564

    Confidences:

    Type
    Value
    No records found.

    7
    EBI-354921
     logo
    HSPA5
    GRP78
    Heat shock 70 kDa protein 5

    [+2]
    78 kDa glucose-regulated protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 78 kDa glucose-regulated protein

    Participant: 78 kDa glucose-regulated protein

    Accession: EBI-1643997

    Name: EBI-354921

    P
    Participant: 78 kDa glucose-regulated protein

    Participant: 78 kDa glucose-regulated protein

    Accession: EBI-1643997

    Name: EBI-354921

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 78 kDa glucose-regulated protein

    Participant: 78 kDa glucose-regulated protein

    Accession: EBI-1643997

    Name: EBI-354921

    Stoichiometry: 0.0

    F
    Participant: 78 kDa glucose-regulated protein

    Participant: 78 kDa glucose-regulated protein

    Accession: EBI-1643997

    Name: EBI-354921

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 78 kDa glucose-regulated protein

    Participant: 78 kDa glucose-regulated protein

    Accession: EBI-1643997

    Name: EBI-354921

    Confidences:

    Type
    Value
    No records found.

    8
    EBI-347088
     logo
    YWHAZ
    Protein kinase C inhibitor protein 1
    14-3-3 protein zeta/delta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein zeta/delta

    Participant: 14-3-3 protein zeta/delta

    Accession: EBI-1643998

    Name: EBI-347088

    P
    Participant: 14-3-3 protein zeta/delta

    Participant: 14-3-3 protein zeta/delta

    Accession: EBI-1643998

    Name: EBI-347088

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein zeta/delta

    Participant: 14-3-3 protein zeta/delta

    Accession: EBI-1643998

    Name: EBI-347088

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein zeta/delta

    Participant: 14-3-3 protein zeta/delta

    Accession: EBI-1643998

    Name: EBI-347088

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein zeta/delta

    Participant: 14-3-3 protein zeta/delta

    Accession: EBI-1643998

    Name: EBI-347088

    Confidences:

    Type
    Value
    No records found.

    9
    EBI-359854
     logo
    YWHAQ
    14-3-3 protein tau
    14-3-3 protein T-cell

    [+1]
    14-3-3 protein theta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-1643999

    Name: EBI-359854

    P
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-1643999

    Name: EBI-359854

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-1643999

    Name: EBI-359854

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-1643999

    Name: EBI-359854

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein theta

    Participant: 14-3-3 protein theta

    Accession: EBI-1643999

    Name: EBI-359854

    Confidences:

    Type
    Value
    No records found.

    10
    EBI-740559
     logo
    PHKB
    Phosphorylase b kinase regulatory subunit beta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Phosphorylase b kinase regulatory subunit beta

    Participant: Phosphorylase b kinase regulatory subunit beta

    Accession: EBI-1644000

    Name: EBI-740559

    P
    Participant: Phosphorylase b kinase regulatory subunit beta

    Participant: Phosphorylase b kinase regulatory subunit beta

    Accession: EBI-1644000

    Name: EBI-740559

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Phosphorylase b kinase regulatory subunit beta

    Participant: Phosphorylase b kinase regulatory subunit beta

    Accession: EBI-1644000

    Name: EBI-740559

    Stoichiometry: 0.0

    F
    Participant: Phosphorylase b kinase regulatory subunit beta

    Participant: Phosphorylase b kinase regulatory subunit beta

    Accession: EBI-1644000

    Name: EBI-740559

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Phosphorylase b kinase regulatory subunit beta

    Participant: Phosphorylase b kinase regulatory subunit beta

    Accession: EBI-1644000

    Name: EBI-740559

    Confidences:

    Type
    Value
    No records found.

    11
    EBI-351896
     logo
    HSPA8
    HSC70
    HSP73

    [+3]
    Heat shock cognate 71 kDa protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-1644001

    Name: EBI-351896

    P
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-1644001

    Name: EBI-351896

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-1644001

    Name: EBI-351896

    Stoichiometry: 0.0

    F
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-1644001

    Name: EBI-351896

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Heat shock cognate 71 kDa protein

    Participant: Heat shock cognate 71 kDa protein

    Accession: EBI-1644001

    Name: EBI-351896

    Confidences:

    Type
    Value
    No records found.

    12
    EBI-365961
     logo
    ARAF
    PKS
    PKS2

    [+4]
    Serine/threonine-protein kinase A-Raf
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Serine/threonine-protein kinase A-Raf

    Participant: Serine/threonine-protein kinase A-Raf

    Accession: EBI-1644002

    Name: EBI-365961

    P
    Participant: Serine/threonine-protein kinase A-Raf

    Participant: Serine/threonine-protein kinase A-Raf

    Accession: EBI-1644002

    Name: EBI-365961

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Serine/threonine-protein kinase A-Raf

    Participant: Serine/threonine-protein kinase A-Raf

    Accession: EBI-1644002

    Name: EBI-365961

    Stoichiometry: 0.0

    F
    Participant: Serine/threonine-protein kinase A-Raf

    Participant: Serine/threonine-protein kinase A-Raf

    Accession: EBI-1644002

    Name: EBI-365961

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Serine/threonine-protein kinase A-Raf

    Participant: Serine/threonine-protein kinase A-Raf

    Accession: EBI-1644002

    Name: EBI-365961

    Confidences:

    Type
    Value
    No records found.

    13
    EBI-306940
     logo
    YWHAH
    YWHA1
    Protein AS1
    14-3-3 protein eta
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein eta

    Participant: 14-3-3 protein eta

    Accession: EBI-1644003

    Name: EBI-306940

    P
    Participant: 14-3-3 protein eta

    Participant: 14-3-3 protein eta

    Accession: EBI-1644003

    Name: EBI-306940

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein eta

    Participant: 14-3-3 protein eta

    Accession: EBI-1644003

    Name: EBI-306940

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein eta

    Participant: 14-3-3 protein eta

    Accession: EBI-1644003

    Name: EBI-306940

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein eta

    Participant: 14-3-3 protein eta

    Accession: EBI-1644003

    Name: EBI-306940

    Confidences:

    Type
    Value
    No records found.

    14
    EBI-444403
     logo
    LIMK1
    LIMK
    LIM domain kinase 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: LIM domain kinase 1

    Participant: LIM domain kinase 1

    Accession: EBI-1644004

    Name: EBI-444403

    P
    Participant: LIM domain kinase 1

    Participant: LIM domain kinase 1

    Accession: EBI-1644004

    Name: EBI-444403

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: LIM domain kinase 1

    Participant: LIM domain kinase 1

    Accession: EBI-1644004

    Name: EBI-444403

    Stoichiometry: 0.0

    F
    Participant: LIM domain kinase 1

    Participant: LIM domain kinase 1

    Accession: EBI-1644004

    Name: EBI-444403

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: LIM domain kinase 1

    Participant: LIM domain kinase 1

    Accession: EBI-1644004

    Name: EBI-444403

    Confidences:

    Type
    Value
    No records found.

    15
    EBI-359832
     logo
    YWHAG
    Protein kinase C inhibitor protein 1
    14-3-3 protein gamma
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-1644005

    Name: EBI-359832

    P
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-1644005

    Name: EBI-359832

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-1644005

    Name: EBI-359832

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-1644005

    Name: EBI-359832

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein gamma

    Participant: 14-3-3 protein gamma

    Accession: EBI-1644005

    Name: EBI-359832

    Confidences:

    Type
    Value
    No records found.

    16
    EBI-356498
     logo
    YWHAE
    14-3-3 protein epsilon
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: 14-3-3 protein epsilon

    Participant: 14-3-3 protein epsilon

    Accession: EBI-1644006

    Name: EBI-356498

    P
    Participant: 14-3-3 protein epsilon

    Participant: 14-3-3 protein epsilon

    Accession: EBI-1644006

    Name: EBI-356498

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: 14-3-3 protein epsilon

    Participant: 14-3-3 protein epsilon

    Accession: EBI-1644006

    Name: EBI-356498

    Stoichiometry: 0.0

    F
    Participant: 14-3-3 protein epsilon

    Participant: 14-3-3 protein epsilon

    Accession: EBI-1644006

    Name: EBI-356498

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: 14-3-3 protein epsilon

    Participant: 14-3-3 protein epsilon

    Accession: EBI-1644006

    Name: EBI-356498

    Confidences:

    Type
    Value
    No records found.

    17
    EBI-295634
     logo
    CDC37
    Hsp90 chaperone protein kinase-targeting subunit
    p50Cdc37

    [+1]
    Hsp90 co-chaperone Cdc37
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    so
    SO:0000358
    -
    see-also
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-1644007

    Name: EBI-295634

    P
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-1644007

    Name: EBI-295634

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-1644007

    Name: EBI-295634

    Stoichiometry: 0.0

    F
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-1644007

    Name: EBI-295634

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Hsp90 co-chaperone Cdc37

    Participant: Hsp90 co-chaperone Cdc37

    Accession: EBI-1644007

    Name: EBI-295634

    Confidences:

    Type
    Value
    No records found.


    Graphical Representation of Experimental Features