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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 17721511

Journal: Nat. Biotechnol. (1087-0156)

Year of Publication: 2007

Title: Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

Author List: Bantscheff M., Eberhard D., Abraham Y., Bastuck S., Boesche M., Hobson S., Mathieson T., Perrin J., Raida M., Rau C., Reader V., Sweetman G., Bauer A., Bouwmeester T., Hopf C., Kruse U., Neubauer G., Ramsden N., Rick J., Kuster B., Drewes G.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Apoptosis - Interactions involving proteins with a function related to apoptosis

Experiment (12 interactions)

Accession: EBI-1379264

Name: bantscheff-2007-1

Host organism: Homo sapiens epitheloid cervix carcinoma cells

Organism: Homo sapiens epitheloid cervix carcinoma cells

Accession: EBI-307614

Name: human-hela

Description: Homo sapiens epitheloid cervix carcinoma cells

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: pull down

Interaction detection method: pull down
Accession: EBI-1223

Name: pull down

Description: pull down

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0096
-
identity


Annotations:
Topic
Text
definition
A specific affinity chromatography method where a molecule of interest (bait) is bound to a column, often via an affinity tag expressed as a protein fusion (GST, HIS tag and others) or chemically linked to the bait molecule . The molecule may be expressed or synthesised and purified first, often in an heterologous system, bound to the matrix at high concentration and then challenged with a solution or cellular extract containing the candidate partner molecules. Alternatively, a multi-molecular complex may be adsorbed to the resin and the retained binding molecules subsequently identified.


Participant Identification Method: fingerprinting

Participant identification method: fingerprinting
Accession: EBI-70

Name: fingerprinting

Description: peptide massfingerprinting

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
10967324
-
primary-reference
pubmed
11805826
-
see-also
psi-mi
MI:0082
-
identity
pubmed
11752590
-
method reference


Annotations:
Topic
Text
definition
This approach leads to protein identification by matching peptide masses, as measured by mass spectrometry, to the ones calculated from in silico fragmentation of a protein sequence database. A peptide mixture from a tryptic digest is analysed by MALDI-MS (Matrix-assisted laser desorption ionization mass spectrometry). The list of peptide masses obtained by MALDI MS is automatically compared to the calculated masses of the predicted peptide fragments for each entry in the database. High mass accuracy is very important in order to obtain a statistically significant and unambiguous match This method is best applied to completely sequenced genomes and well characterised proteomes. However, depending on the data quality, proteins that are highly homologous to already characterised proteins (greater than 80 to 90% sequence identity) can also be identified. The retrieved sequence are evaluated by mass accuracy of the peptides, matching of additional peptide masses in the MALDI spectrum after accounting for common modifications such as oxidation, acrylamidation of cysteine and missed cleavages and the use of secondary information (apparent isoelectric point and molecular weight). If any ambiguity about the identification by MALDI-MS still exists, the results must verified by an other identification method. Peptide mass fingerprint is generally carried out with a MALDI-TOF (Matrix-assisted laser desorption ionization time-of-flight ) instrument but can also be achieved ESI-TOF (Electrospray Ionisation time-of-flight) or LC-MS (Liquid Chromatography-Mass Spectrometry) mass spectrometer.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Bernhard.kuster@cellzome.com
The authors used immobilized non-selective kinase inhibitors (kinobeads) to pull down proteins from cell lysates and the bound proteins were quantified in parallel by mass spectrometry .
Most IPI protein identifiers supplied by the authors were mapped to UniProt accession numbers using the PICR tool (http://www.ebi.ac.uk/Tools/picr/). Proteins which could not be mapped using the above approach were mapped by sequence similarity (cut off 98% sequence similarity over the query sequence). Some proteins could not be mapped using these approaches; these were IPI00012318, IPI00019473, IPI00025644, IPI00052361, IPI00068256, IPI00180434, IPI00183850, IPI00185860, IPI00457307, IPI00640698, IPI00657720, IPI00658151 and IPI00019473. These unmapped proteins appear as unassigned protein entries indicated by an EBI-XXXXXXX identifier.
2007-08-16: M.Bantscheff, Cellzome AG, Heidelberg, Germany
Only protein-protein interactions
-
imex curation

Interaction

Accession: EBI-1383737

Name: purvalanol-abl1

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Participants (79)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp1234pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp1234pp
1
EBI-1380990
 logo
Purvalanol B
Organism Details

Accession:

Name:

-
In vitro
Expressed In Details

Accession: EBI-1318

Name: in vitro

Description: In vitro

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
�Host Organism' is in vitro on experiments when one of the interacting proteins is extracellular or has an extracellular domain that participates in the interaction and /or the interaction is shown to occur in a tube.
The term is also used to indicate in vitro produced protein e.g. by coupled in vitro transcription translation system.
1. Interaction between a cellsurface receptor and a labelled purified protein ligand; 2. Two cells each of which express cellsurface molecules and are demonstrated to interact; 3. One cell expressing two or more cellsurface molecules which are demonstrated to interact.

bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0496
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


small molecule
Interactor type: small molecule
Accession: EBI-619656

Name: small molecule

Description: small molecule

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0328
-
identity


Annotations:
Topic
Text
definition
Molecule not part of or directly encoded by the genome, encompasses any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity.


A
Participant: Purvalanol B

Participant: Purvalanol B

Accession: EBI-1383738

Name: EBI-1380990

P
Participant: Purvalanol B

Participant: Purvalanol B

Accession: EBI-1383738

Name: EBI-1380990

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Purvalanol B

Participant: Purvalanol B

Accession: EBI-1383738

Name: EBI-1380990

Stoichiometry: 0.0

F
Participant: Purvalanol B

Participant: Purvalanol B

Accession: EBI-1383738

Name: EBI-1380990

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Purvalanol B

Participant: Purvalanol B

Accession: EBI-1383738

Name: EBI-1380990

Confidences:

Type
Value
No records found.

2
EBI-1383454
 logo
dastyLogo
TYK2
Non-receptor tyrosine-protein kinase TYK2
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Non-receptor tyrosine-protein kinase TYK2

Participant: Non-receptor tyrosine-protein kinase TYK2

Accession: EBI-1383692

Name: EBI-1383454

P
Participant: Non-receptor tyrosine-protein kinase TYK2

Participant: Non-receptor tyrosine-protein kinase TYK2

Accession: EBI-1383692

Name: EBI-1383454

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Non-receptor tyrosine-protein kinase TYK2

Participant: Non-receptor tyrosine-protein kinase TYK2

Accession: EBI-1383692

Name: EBI-1383454

Stoichiometry: 0.0

F
Participant: Non-receptor tyrosine-protein kinase TYK2

Participant: Non-receptor tyrosine-protein kinase TYK2

Accession: EBI-1383692

Name: EBI-1383454

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Non-receptor tyrosine-protein kinase TYK2

Participant: Non-receptor tyrosine-protein kinase TYK2

Accession: EBI-1383692

Name: EBI-1383454

Confidences:

Type
Value
No records found.

3
EBI-1383687
 logo
dastyLogo
CAMK2A
CAMKA
KIAA0968
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Accession: EBI-1383693

Name: EBI-1383687

P
Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Accession: EBI-1383693

Name: EBI-1383687

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Accession: EBI-1383693

Name: EBI-1383687

Stoichiometry: 0.0

F
Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Accession: EBI-1383693

Name: EBI-1383687

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Participant: Calcium/calmodulin-dependent protein kinase type II subunit alpha

Accession: EBI-1383693

Name: EBI-1383687

Confidences:

Type
Value
No records found.

4
EBI-73946
 logo
dastyLogo
Mitogen-activated protein kinase p38 alpha
Cytokine suppressive anti-inflammatory drug-binding protein
MAX-interacting protein 2

[+9]
Mitogen-activated protein kinase 14
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Mitogen-activated protein kinase 14

Participant: Mitogen-activated protein kinase 14

Accession: EBI-1383694

Name: EBI-73946

P
Participant: Mitogen-activated protein kinase 14

Participant: Mitogen-activated protein kinase 14

Accession: EBI-1383694

Name: EBI-73946

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Mitogen-activated protein kinase 14

Participant: Mitogen-activated protein kinase 14

Accession: EBI-1383694

Name: EBI-73946

Stoichiometry: 0.0

F
Participant: Mitogen-activated protein kinase 14

Participant: Mitogen-activated protein kinase 14

Accession: EBI-1383694

Name: EBI-73946

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Mitogen-activated protein kinase 14

Participant: Mitogen-activated protein kinase 14

Accession: EBI-1383694

Name: EBI-73946

Confidences:

Type
Value
No records found.

5
EBI-49961
 logo
dastyLogo
Mixed lineage kinase 3
Src-homology 3 domain-containing proline-rich kinase
SPRK

[+3]
Mitogen-activated protein kinase kinase kinase 11
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Mitogen-activated protein kinase kinase kinase 11

Participant: Mitogen-activated protein kinase kinase kinase 11

Accession: EBI-1383695

Name: EBI-49961

P
Participant: Mitogen-activated protein kinase kinase kinase 11

Participant: Mitogen-activated protein kinase kinase kinase 11

Accession: EBI-1383695

Name: EBI-49961

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Mitogen-activated protein kinase kinase kinase 11

Participant: Mitogen-activated protein kinase kinase kinase 11

Accession: EBI-1383695

Name: EBI-49961

Stoichiometry: 0.0

F
Participant: Mitogen-activated protein kinase kinase kinase 11

Participant: Mitogen-activated protein kinase kinase kinase 11

Accession: EBI-1383695

Name: EBI-49961

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Mitogen-activated protein kinase kinase kinase 11

Participant: Mitogen-activated protein kinase kinase kinase 11

Accession: EBI-1383695

Name: EBI-49961

Confidences:

Type
Value
No records found.

6
EBI-1383726
 logo
dastyLogo
CSNK1A1
CK1
Casein kinase I isoform alpha
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Casein kinase I isoform alpha

Participant: Casein kinase I isoform alpha

Accession: EBI-1383696

Name: EBI-1383726

P
Participant: Casein kinase I isoform alpha

Participant: Casein kinase I isoform alpha

Accession: EBI-1383696

Name: EBI-1383726

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Casein kinase I isoform alpha

Participant: Casein kinase I isoform alpha

Accession: EBI-1383696

Name: EBI-1383726

Stoichiometry: 0.0

F
Participant: Casein kinase I isoform alpha

Participant: Casein kinase I isoform alpha

Accession: EBI-1383696

Name: EBI-1383726

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Casein kinase I isoform alpha

Participant: Casein kinase I isoform alpha

Accession: EBI-1383696

Name: EBI-1383726

Confidences:

Type
Value
No records found.

7
EBI-366978
 logo
dastyLogo
NLK
LAK1
Nemo-like kinase

[+1]
Serine/threonine-protein kinase NLK
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Serine/threonine-protein kinase NLK

Participant: Serine/threonine-protein kinase NLK

Accession: EBI-1383697

Name: EBI-366978

P
Participant: Serine/threonine-protein kinase NLK

Participant: Serine/threonine-protein kinase NLK

Accession: EBI-1383697

Name: EBI-366978

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Serine/threonine-protein kinase NLK

Participant: Serine/threonine-protein kinase NLK

Accession: EBI-1383697

Name: EBI-366978

Stoichiometry: 0.0

F
Participant: Serine/threonine-protein kinase NLK

Participant: Serine/threonine-protein kinase NLK

Accession: EBI-1383697

Name: EBI-366978

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Serine/threonine-protein kinase NLK

Participant: Serine/threonine-protein kinase NLK

Accession: EBI-1383697

Name: EBI-366978

Confidences:

Type
Value
No records found.

8
EBI-1245958
 logo
dastyLogo
CDK7
MO15
CAK

[+8]
Cyclin-dependent kinase 7
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Cyclin-dependent kinase 7

Participant: Cyclin-dependent kinase 7

Accession: EBI-1383698

Name: EBI-1245958

P
Participant: Cyclin-dependent kinase 7

Participant: Cyclin-dependent kinase 7

Accession: EBI-1383698

Name: EBI-1245958

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Cyclin-dependent kinase 7

Participant: Cyclin-dependent kinase 7

Accession: EBI-1383698

Name: EBI-1245958

Stoichiometry: 0.0

F
Participant: Cyclin-dependent kinase 7

Participant: Cyclin-dependent kinase 7

Accession: EBI-1383698

Name: EBI-1245958

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Cyclin-dependent kinase 7

Participant: Cyclin-dependent kinase 7

Accession: EBI-1383698

Name: EBI-1245958

Confidences:

Type
Value
No records found.

9
EBI-722467
 logo
dastyLogo
90 kDa ribosomal protein S6 kinase 6
Ribosomal S6 kinase 4
pp90RSK4

[+2]
Ribosomal protein S6 kinase alpha-6
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Ribosomal protein S6 kinase alpha-6

Participant: Ribosomal protein S6 kinase alpha-6

Accession: EBI-1383700

Name: EBI-722467

P
Participant: Ribosomal protein S6 kinase alpha-6

Participant: Ribosomal protein S6 kinase alpha-6

Accession: EBI-1383700

Name: EBI-722467

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Ribosomal protein S6 kinase alpha-6

Participant: Ribosomal protein S6 kinase alpha-6

Accession: EBI-1383700

Name: EBI-722467

Stoichiometry: 0.0

F
Participant: Ribosomal protein S6 kinase alpha-6

Participant: Ribosomal protein S6 kinase alpha-6

Accession: EBI-1383700

Name: EBI-722467

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Ribosomal protein S6 kinase alpha-6

Participant: Ribosomal protein S6 kinase alpha-6

Accession: EBI-1383700

Name: EBI-722467

Confidences:

Type
Value
No records found.

10
EBI-914695
 logo
dastyLogo
WEE1
Wee1A kinase
Wee1-like protein kinase
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Wee1-like protein kinase

Participant: Wee1-like protein kinase

Accession: EBI-1383701

Name: EBI-914695

P
Participant: Wee1-like protein kinase

Participant: Wee1-like protein kinase

Accession: EBI-1383701

Name: EBI-914695

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Wee1-like protein kinase

Participant: Wee1-like protein kinase

Accession: EBI-1383701

Name: EBI-914695

Stoichiometry: 0.0

F
Participant: Wee1-like protein kinase

Participant: Wee1-like protein kinase

Accession: EBI-1383701

Name: EBI-914695

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Wee1-like protein kinase

Participant: Wee1-like protein kinase

Accession: EBI-1383701

Name: EBI-914695

Confidences:

Type
Value
No records found.

11
EBI-748380
 logo
dastyLogo
CK1G2
CSNK1G2
Casein kinase I isoform gamma-2
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Casein kinase I isoform gamma-2

Participant: Casein kinase I isoform gamma-2

Accession: EBI-1383702

Name: EBI-748380

P
Participant: Casein kinase I isoform gamma-2

Participant: Casein kinase I isoform gamma-2

Accession: EBI-1383702

Name: EBI-748380

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Casein kinase I isoform gamma-2

Participant: Casein kinase I isoform gamma-2

Accession: EBI-1383702

Name: EBI-748380

Stoichiometry: 0.0

F
Participant: Casein kinase I isoform gamma-2

Participant: Casein kinase I isoform gamma-2

Accession: EBI-1383702

Name: EBI-748380

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Casein kinase I isoform gamma-2

Participant: Casein kinase I isoform gamma-2

Accession: EBI-1383702

Name: EBI-748380

Confidences:

Type
Value
No records found.

12
EBI-1041567
 logo
dastyLogo
CDK5
Cell division protein kinase 5
Tau protein kinase II catalytic subunit

[+2]
Cyclin-dependent-like kinase 5
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Cyclin-dependent-like kinase 5

Participant: Cyclin-dependent-like kinase 5

Accession: EBI-1383703

Name: EBI-1041567

P
Participant: Cyclin-dependent-like kinase 5

Participant: Cyclin-dependent-like kinase 5

Accession: EBI-1383703

Name: EBI-1041567

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Cyclin-dependent-like kinase 5

Participant: Cyclin-dependent-like kinase 5

Accession: EBI-1383703

Name: EBI-1041567

Stoichiometry: 0.0

F
Participant: Cyclin-dependent-like kinase 5

Participant: Cyclin-dependent-like kinase 5

Accession: EBI-1383703

Name: EBI-1041567

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Cyclin-dependent-like kinase 5

Participant: Cyclin-dependent-like kinase 5

Accession: EBI-1383703

Name: EBI-1041567

Confidences:

Type
Value
No records found.

13
EBI-621482
 logo
dastyLogo
pp60c-src
SRC
SRC1

[+1]
Proto-oncogene tyrosine-protein kinase Src
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Proto-oncogene tyrosine-protein kinase Src

Participant: Proto-oncogene tyrosine-protein kinase Src

Accession: EBI-1383704

Name: EBI-621482

P
Participant: Proto-oncogene tyrosine-protein kinase Src

Participant: Proto-oncogene tyrosine-protein kinase Src

Accession: EBI-1383704

Name: EBI-621482

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Proto-oncogene tyrosine-protein kinase Src

Participant: Proto-oncogene tyrosine-protein kinase Src

Accession: EBI-1383704

Name: EBI-621482

Stoichiometry: 0.0

F
Participant: Proto-oncogene tyrosine-protein kinase Src

Participant: Proto-oncogene tyrosine-protein kinase Src

Accession: EBI-1383704

Name: EBI-621482

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Proto-oncogene tyrosine-protein kinase Src

Participant: Proto-oncogene tyrosine-protein kinase Src

Accession: EBI-1383704

Name: EBI-621482

Confidences:

Type
Value
No records found.

14
EBI-475899
 logo
dastyLogo
INSR
Insulin receptor
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Insulin receptor

Participant: Insulin receptor

Accession: EBI-1383705

Name: EBI-475899

P
Participant: Insulin receptor

Participant: Insulin receptor

Accession: EBI-1383705

Name: EBI-475899

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Insulin receptor

Participant: Insulin receptor

Accession: EBI-1383705

Name: EBI-475899

Stoichiometry: 0.0

F
Participant: Insulin receptor

Participant: Insulin receptor

Accession: EBI-1383705

Name: EBI-475899

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Insulin receptor

Participant: Insulin receptor

Accession: EBI-1383705

Name: EBI-475899

Confidences:

Type
Value
No records found.

15
EBI-1181405
 logo
dastyLogo
PRKAA1
AMPK1
Tau-protein kinase PRKAA1

[+2]
5'-AMP-activated protein kinase catalytic subunit alpha-1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Accession: EBI-1383706

Name: EBI-1181405

P
Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Accession: EBI-1383706

Name: EBI-1181405

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Accession: EBI-1383706

Name: EBI-1181405

Stoichiometry: 0.0

F
Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Accession: EBI-1383706

Name: EBI-1181405

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Participant: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Accession: EBI-1383706

Name: EBI-1181405

Confidences:

Type
Value
No records found.

16
EBI-1383732
 logo
dastyLogo
SRC2
Proto-oncogene c-Fgr
FGR

[+4]
Tyrosine-protein kinase Fgr
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Tyrosine-protein kinase Fgr

Participant: Tyrosine-protein kinase Fgr

Accession: EBI-1383707

Name: EBI-1383732

P
Participant: Tyrosine-protein kinase Fgr

Participant: Tyrosine-protein kinase Fgr

Accession: EBI-1383707

Name: EBI-1383732

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Tyrosine-protein kinase Fgr

Participant: Tyrosine-protein kinase Fgr

Accession: EBI-1383707

Name: EBI-1383732

Stoichiometry: 0.0

F
Participant: Tyrosine-protein kinase Fgr

Participant: Tyrosine-protein kinase Fgr

Accession: EBI-1383707

Name: EBI-1383732

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Tyrosine-protein kinase Fgr

Participant: Tyrosine-protein kinase Fgr

Accession: EBI-1383707

Name: EBI-1383732

Confidences:

Type
Value
No records found.

17
EBI-749343
 logo
dastyLogo
CSNK1E
Casein kinase I isoform epsilon
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Casein kinase I isoform epsilon

Participant: Casein kinase I isoform epsilon

Accession: EBI-1383708

Name: EBI-749343

P
Participant: Casein kinase I isoform epsilon

Participant: Casein kinase I isoform epsilon

Accession: EBI-1383708

Name: EBI-749343

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Casein kinase I isoform epsilon

Participant: Casein kinase I isoform epsilon

Accession: EBI-1383708

Name: EBI-749343

Stoichiometry: 0.0

F
Participant: Casein kinase I isoform epsilon

Participant: Casein kinase I isoform epsilon

Accession: EBI-1383708

Name: EBI-749343

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Casein kinase I isoform epsilon

Participant: Casein kinase I isoform epsilon

Accession: EBI-1383708

Name: EBI-749343

Confidences:

Type
Value
No records found.

18
EBI-1383814
 logo
dastyLogo
CSNK1G1
Casein kinase I isoform gamma-1
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Casein kinase I isoform gamma-1

Participant: Casein kinase I isoform gamma-1

Accession: EBI-1383709

Name: EBI-1383814

P
Participant: Casein kinase I isoform gamma-1

Participant: Casein kinase I isoform gamma-1

Accession: EBI-1383709

Name: EBI-1383814

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Casein kinase I isoform gamma-1

Participant: Casein kinase I isoform gamma-1

Accession: EBI-1383709

Name: EBI-1383814

Stoichiometry: 0.0

F
Participant: Casein kinase I isoform gamma-1

Participant: Casein kinase I isoform gamma-1

Accession: EBI-1383709

Name: EBI-1383814

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Casein kinase I isoform gamma-1

Participant: Casein kinase I isoform gamma-1

Accession: EBI-1383709

Name: EBI-1383814

Confidences:

Type
Value
No records found.

19
EBI-1383789
 logo
dastyLogo
CSNK1G3
Casein kinase I isoform gamma-3
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Casein kinase I isoform gamma-3

Participant: Casein kinase I isoform gamma-3

Accession: EBI-1383710

Name: EBI-1383789

P
Participant: Casein kinase I isoform gamma-3

Participant: Casein kinase I isoform gamma-3

Accession: EBI-1383710

Name: EBI-1383789

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Casein kinase I isoform gamma-3

Participant: Casein kinase I isoform gamma-3

Accession: EBI-1383710

Name: EBI-1383789

Stoichiometry: 0.0

F
Participant: Casein kinase I isoform gamma-3

Participant: Casein kinase I isoform gamma-3

Accession: EBI-1383710

Name: EBI-1383789

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Casein kinase I isoform gamma-3

Participant: Casein kinase I isoform gamma-3

Accession: EBI-1383710

Name: EBI-1383789

Confidences:

Type
Value
No records found.

20
EBI-375096
 logo
dastyLogo
CDK2
p33 protein kinase
Cell division protein kinase 2

[+1]
Cyclin-dependent kinase 2
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Homo sapiens
Expressed In Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

prey
Experimental role: prey
Accession: EBI-58

Name: prey

Description: prey

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0498
-
identity


Annotations:
Topic
Text
definition
Molecule experimentally identified as being captured by a given bait.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0499
-
identity


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also
psi-mi
MI:0326
-
identity


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Cyclin-dependent kinase 2

Participant: Cyclin-dependent kinase 2

Accession: EBI-1383711

Name: EBI-375096

P
Participant: Cyclin-dependent kinase 2

Participant: Cyclin-dependent kinase 2

Accession: EBI-1383711

Name: EBI-375096

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Cyclin-dependent kinase 2

Participant: Cyclin-dependent kinase 2

Accession: EBI-1383711

Name: EBI-375096

Stoichiometry: 0.0

F
Participant: Cyclin-dependent kinase 2

Participant: Cyclin-dependent kinase 2

Accession: EBI-1383711

Name: EBI-375096

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
No records found.

C
Participant: Cyclin-dependent kinase 2

Participant: Cyclin-dependent kinase 2

Accession: EBI-1383711

Name: EBI-375096

Confidences:

Type
Value
No records found.