6-phosphofructokinase, L4 homotetramer

Species: Rattus norvegicus (Rat); 10116
Accession number: EBI-822916

Summary


Systematic Name:

Pfkl tetramer

Synonyms:
Phosphofructokinase, liver-type homotetramer PFK-L4 6-phosphofructokinase
phosphofructokinase phosphohexokinase 6PF-1-K
Pfk-1 PFK
Function:

Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate in the presence of MgATP, the first irreversible step for glycolysis. Predominant form in the liver.

Properties:

Inhibited by ATP and citrate; activated by glucose 1,6 diphosphate.

Complex Assembly:

Homotetramer


Participants

ID Name Description Stochiometry Biological Role Interactor Type Linked Features Other Features
P30835
EBI-822904
Pfkl ATP-dependent 6-phosphofructokinase, liver type 4 unspecified role protein

Cross References

Type Database Identifier Description
evidence ontology ECO:0000266
biological process gene ontology GO:0006096 glycolytic process
cellular component gene ontology GO:0005945 6-phosphofructokinase complex
molecular function gene ontology GO:0003872 6-phosphofructokinase activity
evidence has been inferred from this entry intact EBI-764772
identical object in an external resource intenz 2.7.1.11
additional information pubmed 11949936