6-phosphofructokinase, M4 homotetramer

Species: Rattus norvegicus (Rat); 10116
Accession number: EBI-822887

Summary


Systematic Name:

Pfkm tetramer

Synonyms:
Phosphofructokinase, muscle-type homotetramer PFK-M4
6-phosphofructokinase phosphofructokinase
phosphohexokinase 6PF-1-K
Pfk-1 PFK
Function:

Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate in the presence of MgATP, the first irreversible step for glycolysis. Predominant form in skeletal muscle.

Properties:

Inhibited by ATP and citrate; activated by glucose 1,6 diphosphate.

Complex Assembly:

Homotetramer


Participants

ID Name Description Stochiometry Biological Role Interactor Type Other Features
P47858
EBI-822894
Pfkm ATP-dependent 6-phosphofructokinase, muscle type 4 unspecified role protein

Cross References

Type Database Identifier Description
evidence ontology ECO:0000266
biological process gene ontology GO:0006096 glycolysis
cellular component gene ontology GO:0005945 6-phosphofructokinase complex
molecular function gene ontology GO:0003872 6-phosphofructokinase activity
inferred-from intact EBI-764595
identical object in an external resource intenz 2.7.1.11
additional information pubmed 11949936