6-phosphofructokinase, M3L heterotetramer

Species: Homo sapiens; 9606
Accession number: EBI-764934

Summary


Systematic Name:

PFKL:3xPFKM

Synonyms:
PFK-M3L 6-phosphofructokinase phosphofructokinase
phosphohexokinase 6PF-1-K Pfk-1
PFK
Function:

Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate in the presence of MgATP, the first irreversible step for glycolysis. Present in the erythrocyte.

Complex Assembly:

Heterotetramer


Participants

ID Name Description Stochiometry Biological Role Interactor Type Linked Features Other Features
P08237
EBI-514788
PFKM ATP-dependent 6-phosphofructokinase, muscle type 3 enzyme protein
binding-associated region P17858 [?-?]
P17858
EBI-487243
PFKL ATP-dependent 6-phosphofructokinase, liver type 1 enzyme protein
binding-associated region P08237 [?-?]

Cross References

Type Database Identifier Description
evidence ontology ECO:0000353
biological process gene ontology GO:0006096 glycolytic process
cellular component gene ontology GO:0005945 6-phosphofructokinase complex
molecular function gene ontology GO:0003872 6-phosphofructokinase activity
Experimental evidence that interaction occurs intact EBI-514817
identical object in an external resource intenz 2.7.1.11
identical object in an external resource protein ontology PR:000027413
additional information pubmed 11949936
identical object in an external resource reactome REACT_5445.1