BIM:BCL-XL complex

Species: Homo sapiens; 9606
Accession number: EBI-706896

Summary


Systematic Name:

BCL2L1:BCL2L11

Synonyms:
BIM:BCL-XL BIM:BCLXL BCL-XL:BIM
BCLXL:BIM
Function:

BH3 domain-containing BIM interacts with and inhibits anti-apoptotic BCL-XL.

Complex Assembly:

Heterodimer


Participants

ID Name Description Stochiometry Biological Role Interactor Type Linked Features Other Features
O43521
EBI-526406
BCL2L11 Bcl-2-like protein 11 1 unspecified role protein
binding-associated region Q07817-1 [?-?]
Q07817-1
EBI-287195
BCL2L1 Bcl-2-like protein 1 1 unspecified role protein
binding-associated region O43521 [?-?]

Cross References

Type Database Identifier Description
evidence ontology ECO:0000353
biological process gene ontology GO:0043065 positive regulation of apoptotic process
cellular component gene ontology GO:0097140 BIM-BCL-xl complex
Experimental evidence that interaction occurs intact EBI-701297
Experimental evidence that interaction occurs intact EBI-701497
additional information pubmed 14634621
identical object in an external resource reactome REACT_4393.1