Maltose transport complex

Species: Escherichia coli (strain K12); 83333
Accession number: EBI-6477643

Summary


Systematic Name:

malE:malF:malG:2xmalK

Synonyms:
MalE-MalFGK2 complex maltose transporter maltose transporter malE-MalFGK2
maltose transporter MalE-MalFGK2 complex maltose-transporting ATPase maltose ATP-binding cassette (ABC) transporter complex
ATP phosphohydrolase (maltose-importing)
Function:

Transports maltose from the periplasmic space into the cytoplasm through an ATP-dependent transmembrane channel. Maltose binds to malE which attaches to the malFG dimer. Upon release of the maltose into the transmembrane channel, the malK2 dimer binds ATP the hydrolysis of which triggers the release of maltose into the cytoplasm.

Properties:

Consists of periplasmic maltose binding protein MalE (P0AEX9), transmembrane MalF-MalG dimer (P02916-P68183) and cytoplasmic ATPase subunit MalK dimer (P68187).

Ligand:

maltose (CHEBI:17306)

Complex Assembly:

Heteropentamer


Participants

ID Name Description Stochiometry Biological Role Interactor Type Linked Features Other Features
P68187
EBI-550803
malK Maltose/maltodextrin import ATP-binding protein MalK 2 enzyme protein
binding-associated region P02916 [1-371]
binding-associated region CHEBI:17306 [1-371]
binding-associated region P68183 [1-371]
binding-associated region [1-371]
CHEBI:17306
EBI-1774952
maltose Maltose 1 unspecified role small molecule
binding-associated region P68187 [?-?]
binding-associated region P02916 [?-?]
binding-associated region P68183 [?-?]
binding-associated region P0AEX9 [?-?]
P02916
EBI-1118919
malF Maltose transport system permease protein MalF 1 unspecified role protein
binding-associated region P68187 [1-514]
binding-associated region P0AEX9 [1-514]
binding-associated region P68183 [1-514]
binding-associated region CHEBI:17306 [1-514]
P0AEX9
EBI-369910
malE Maltose-binding periplasmic protein 1 unspecified role protein
binding-associated region P68183 [1-396]
binding-associated region P02916 [1-396]
binding-associated region CHEBI:17306 [1-396]
P68183
EBI-6400985
malG Maltose transport system permease protein MalG 1 unspecified role protein
binding-associated region P02916 [1-296]
binding-associated region CHEBI:17306 [1-296]
binding-associated region P68187 [1-296]
binding-associated region P0AEX9 [1-296]

Cross References

Type Database Identifier Description
evidence ontology ECO:0000353
biological process gene ontology GO:0042956 maltodextrin transport
biological process gene ontology GO:1902345 positive regulation of maltose transport
cellular component gene ontology GO:1990060 maltose transport complex
molecular function gene ontology GO:0005524 ATP binding
molecular function gene ontology GO:0015423 maltose-transporting ATPase activity
molecular function gene ontology GO:1901982 maltose binding
Experimental evidence that interaction occurs intact EBI-6477279
identical object in an external resource intenz 3.6.3.19
additional information pubmed 18033289
identical object in an external resource wwpdb 3puy