Previous  Industry workshops at the EBI

Dear Associates,

EBI is hosting a BioStandards Workshop 2-3 December 1999: "EST data analysis". Scientific coordinator: Juha Muilu (EMBL-EBI). Please find below a description of the workshop and a preliminary workshop programme with the talks. The workshop will start at 9:25 on Thursday 2 December and it is expected to end at 16:00 on Friday 3 of December.

Kindest regards and we are looking forward to your registrations.

Bodil Holle.

Description of the workshop:

Expressed sequence tag sequences (ESTs) are short fragments of DNA sequences generated from either end of randomly selected cDNA clones. The main purpose of EST sequencing is to rapidly scan for all the protein coding genes expressed and thereby to provide a "tag" for each gene in the genome. Fast sequencing methods have enabled a rapid increase in the number of EST sequences produced and ESTs now account for the majority of DNA entries in nucleotide sequence databases. The ESTs have proven to be invaluable in various genomic activities such as gene finding, as well as discovery of novel genes, gene expression studies, and identification of SNPs.

This workshop will review the context of EST sequences in Functional Genomics, as well as review the state of art in EST-related biocomputing and bioinformatics activities. The intended audience for the workshop is biologists with computational experience, as well as bioinformaticians.

Thursday, 2 December 1999

09:25 WelcomeOverview
09:30 ESTs, Genes and Gene Expression - A unified view J. Fickett (SmithKline Beecham, USA)
10:20 Coffee breakClustering and resources
10:40 EST clustering: diverse impacts of clustered dataW. Hide (SANBI/UWC, South Africa)
11:30 HGMP-RC's Human Gene Index (HuGen)Peter van Heusden (HGMP-RC, UK)
12:20 Lunch
13:50 JESAMJ. Parsons (Cereon Genomics, USA)
14:40 EST resources for mapping at EBIP. Rodriguez-Tome (EBI, UK)
15:30 Coffee break
15:50 EST database and visualisation of cluster dataJ. Muilu (EBI, UK)
16:40 Genome Annotation : Promises and expectationsA.Thanaraj (EBI, UK)
17:10-17:40 Discussion
17:45 Transport to dinner

Friday, 3 December 1999
Quality and annotation issues

09:00 Quality of EST data in relation to microarray expression profilingR. Houlgatte (TAGC/CIML, France)
9:50 Annotation of ESTsA. Hatzigeorgiou (Synaptic, Greece)
10:40 Coffee breakSpecific Genomic Applications
11:00 Analysis of the C.elegans ESTJ. & D. Thierry-Mieg (CRBM/CNRS, France)
11:50 Lunch
13:05 Prediction of SNPs in EST databases. Applications to disease-associated genes and human evolutionShamil Sunyaev (EMBL, Germany)
13:55 Recognition of alternatively spliced gene products using ESTsM. Gelfand (GosNIIGenetika, Russia)
14:45 Concluding remarks
15:00 Tea and departures