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New Sequencing Technologies And Their Applications In Medicine Workshop

20 - 21 Novembre 2008

Dear Associates,

The EBI will host a New Sequencing Technologies And Their Applications In Medecine Workshop on the 20th to 21st November 2008.

The venue will be the EBI IT Training room.

We would like to invite you to attend this workshop focussing on recent developments in genomics. Its aims are to identify how the commercial and academic opportunities afforded by the sequencing revolution can be realised.

Motivation

Whereas current medical diagnostics is mainly based on patient symptoms, anatomical imaging, blood analysis and tissue pathology, there is a widespread notion that the rapid developments in high-throughput sequencing will have important consequences in medicine.

Some of these are already evident, such as the rapid characterization of new viruses or pathogens. But there are also applications imminent in cancer diagnostics; and an even broader field of ‘personal genomics’ emerges as the costs for a ‘whole-genome’ human sequence drops and the number of individuals for which the full sequence is known will reach a 1000 over the next few years.

Within Europe, the focus of this work will be at the Wellcome Trust Sanger Institute and the EMBL-European Bioinformatics Institute. We have therefore invited speakers from these two institutes to illuminate three perspectives: the technologies, applications in cancer and pathogen characterization, and the perspective of personal genomics.

The programme essentially has three sessions one focussed on technologies, one on applications in personal genomics and one on other types of applications.


Organisers and contacts:

The Coordinator of the EBI Industry Programme is Dr. Dominic Clark (EMBL-EBI). Please send any questions regarding the strategic intent and programme to Dominic Clark (clark@ebi.ac.uk).

We are grateful to Dr. Matthieu Visser (Philips Research) for helpful input on the programme and agenda, to Paul Flicek (EMBL-EBI) and to collaborators at the Wellcome Trust Sanger Institute. Please send any questions regarding logistics to Liz Ford (ford@ebi.ac.uk).

Registration will close on the 7th November 2008, 12:00 British Time.

Agenda:

Time Agenda
Thursday 20 November 2008
11.00 Registration Tea/Coffee
12.00 Lunch
13.05 Welcome, Dr. Dominic Clark (EMBL-EBI)
  Session 1: New Sequencing Technologies - Chair: Dr. harold Swerdlow (WTSI )
13.15 Dr. Harold Swerdlow (WTSI) Introduction to New Sequencing Technologies.
13.35 Dr. Mark Ross (Illumina) Accurate and Rapid Human Genome Sequencing
14.00 Dr. Tony Cox (WTSI) IT for Next Generation Sequencing
14.25

Donna Muzny (Head of Sequencing Operations, Baylor College of Medicine) Completing Genomes in a Next-Generation Production Environment

14.55 Dr Erin Pleasance (WTSI), Whole Cancer Genome Sequencing on the AB SOLiD Platform
15.20 Discussion
15.35 Tea/Coffee
  Session 2: Whole-genome Studies and the Perspective of Personal Genomics
16.00 Dr Paul Flicek (EMBL-EBI) The 1000 genomes project
16.30 Dr. Alexander (Sasha) Wait Zaranek (Harvard University) The Personal Genome Project
17.00 Dr Dan Turner (WTSI) Targeted Resequencing Using Microarrays
17.30 Prof Leena Peltonen (WTSI) Large Scale Genome Studies of Human Diseases
18.00 Discussion
18.15 Close of First day
18.30

Drinks Reception, Hinxton Hall Lounges

19.00 Workshop Dinner, Conference Centre Restaurant, Hinxton Hall
Friday 21 November 2008
09.15 Tea/Coffee
09.30 Lutz Krause (Nestlé Research Center) Computational Characterization of Short-read Metagenomes
  Session 3: Medical Applications
10.00 Dr. Julian Parkhill (WTSI) Pathogen Sequencing
10.30 Prof. Stephan Beck (UCL) Epigenomics
11.00 Tea/Coffee
11.30 Dr. Andy Futreal (WTSI) Cancer Genomics
12.00 Discussion and Documentation of outcomes
12.30 Lunch
13.30 Departures

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