IMGT/HLA Database

Genomic Version Report - 2.8

Due to reported errors in the genomic sequences of a number of alleles, the genomic libraries for HLA-B and HLA-C were temporarily withdrawn from release 2.7. The sequences have now been verified and corrected as necessary. The following table details all the changes between the release 2.7 and 2.8 genomic sequence libraries.

Sequences Added to Genomic Libraries
Allele	IMGT/HLA Acc No	Date	EMBL/Genbank	Comments
A*0253N	HLA01534	2001-10-31	AF416455
A*3201	HLA00101	1989-08-01	AJ555413 U03907
B*0733	HLA01742	2003-04-30	AJ549199
B*0820	HLA01752	2003-05-24	AJ549202
B*1542	HLA00205	1998-07-28	AJ749950 Y15841
B*1577	HLA01743	2003-04-30	AJ549201
B*2706	HLA00227	1987-11-21	AJ292971 U35734 X73578
B*351402	HLA01741	2003-04-30	AJ549200
B*4404	HLA00321	1994-02-03	AJ550735 X75953 X78426 X78427
B*530101	HLA00364	1990-11-04	AJ311599 M58636 U90566
B*6702	HLA01374	2000-11-22	AF321834 AF321835 AF487379 AY050195 AY050196
Cw*0719	HLA01720	2003-03-26	AY233977 AY233978 AY233979
Modified Sequences
Allele	IMGT/HLA Acc No	Date	EMBL/Genbank	Comments
A*020105	HLA01327	2000-09-26	AJ277793	G -> * at gDNA position 1569
B*070201	HLA00132	1987-11-21	AF436098 AJ292075 AJ309047 L47338 M16102 M32317 U29057 U49904 U49905	T deleted at gDNA position 2604
B*0801	HLA00146	1989-08-01	AJ295294 L76093 M24036 M28204 M59841	T deleted at gDNA position 2604
B*0808N	HLA00975	1999-01-06	Y18552	T deleted at gDNA position 2604
B*0819N	HLA01717	2003-02-25	AJ532609	* -> G, gDNA position 3080 and allele was previously incorrectly listed as B*1819N
B*1302	HLA00153	1989-08-01	AF196182 AJ295278 D50291 M19757 M24041	T deleted at gDNA position 2604
B*1308	HLA01476	2001-05-31	AJ295279	T deleted at gDNA position 2604
B*1402	HLA00158	1989-08-01	AJ301657 M24032 M59840 U90558	T->G at gDNA position 665 and T deleted at gDNA position 2604
B*15010101	HLA00162	1989-08-01	AF436090 AJ295140 D50292 L48400 L79939 M28203 M83193 U03859	T deleted at gDNA position 2604
B*1504	HLA00167	1991-11-14	AJ292970 M84382	T deleted at gDNA position 2604
B*15170101	HLA00180	1993-08-09	AJ300181 U01848 U35431	T deleted at gDNA position 2604
B*15170102	HLA01439	2001-02-28	AJ308397	T deleted at gDNA position 2604
B*180101	HLA00213	1989-08-01	AJ310507 M24039 U90559	G -> A, gDNA position 2170 and T deleted at gDNA position 2604
B*270502	HLA00225	1992-07-01	AJ420238 L20086 M12678 M12967 M14013 X03665 X03666 X03945	T deleted at gDNA position 2604
B*350101	HLA00237	1989-08-01	AF436092 AJ420239 L63544 M28109 M28110 M28111 M28112 M28113 M28114 M28115 U11265	T deleted at gDNA position 2604
B*3701	HLA00265	1989-08-01	AJ310358 M32320 U11267	T deleted at gDNA position 2604
B*380201	HLA00268	1993-07-29	AJ297317 AJ308991 AJ308992 L22028	T deleted at gDNA position 2604
B*3910	HLA00284	1996-04-20	AJ237703 U52175 U52176 U56246 Y09058	T deleted at gDNA position 2604
B*40060101	HLA00297	1992-08-13	AJ300180 M95531	T deleted at gDNA position 2604
B*40060102	HLA01430	2001-01-31	AJ292253	T deleted at gDNA position 2604
B*4101	HLA00312	1989-08-01	AJ309193 M24035 U90560	T deleted at gDNA position 2604
B*4201	HLA00315	1989-08-01	AJ309194 M24034	T deleted at gDNA position 2604
B*4409	HLA00326	1996-09-19	AJ309937 X99734	T deleted at gDNA position 2604
B*4423N	HLA01341	2000-10-23	AJ278766 AJ295293	T deleted at gDNA position 2604
B*4501	HLA00329	1991-11-14	AJ458992 U90562 X61710	T deleted at gDNA position 2604
B*4504	HLA01343	2000-10-23	AJ278944	T deleted at gDNA position 2604
B*4601	HLA00331	1989-08-01	AJ310508 M24033	T deleted at gDNA position 2604, C->T at gDNA position 2915
B*47010101	HLA00332	1989-08-01	AJ295141 M19756	T deleted at gDNA position 2604
B*47010102	HLA01437	2001-02-28	AJ308398	T deleted at gDNA position 2604
B*4801	HLA00335	1991-11-14	AJ309139 M84380 U66250	T deleted at gDNA position 2604
B*4901	HLA00340	1989-08-01	AJ311600 M24037 U11263	T deleted at gDNA position 2604
B*510102	HLA00345	1996-04-20	AJ278903 U90611 U90612 U90613 U90614 U52169 U52170	T deleted at gDNA position 2604
B*5501	HLA00368	1991-09-04	AJ310509 M77778	T deleted at gDNA position 2604
B*5512	HLA01553	2001-11-30	AJ420106	T deleted at gDNA position 2604
B*570101	HLA00381	1989-08-01	AF196183 AJ458991 M32318 X55711	G -> A, gDNA position 560, G -> A, gDNA position 667, T -> C, gDNA position 1481, T -> C, gDNA position 2246, G -> A, gDNA position 2325, T deleted at gDNA position 2604, G inserted at gDNA position 2712 and A -> C, gDNA position 2828
B*5801	HLA00386	1989-08-01	AB008102 AF196184 AJ420241 M11799 U52813 U52814 U65395 U65396	T deleted at gDNA position 2604
B*7301	HLA00392	1993-12-30	AJ311601 L24373 U04787 X77658	T deleted at gDNA position 2604
B*7801	HLA00393	1990-11-04	AJ309192 M33573 X61708	T deleted at gDNA position 2604
B*8202	HLA01188	1999-12-22	AJ251755	T deleted at gDNA position 2604
Cw*070402	HLA01554	2001-11-30	AF220290 AF220291 AY064404	C -> T at gDNA position 2664
Sequences Removed From Genomic Libraries
Allele	IMGT/HLA Acc No	Date	EMBL/Genbank	Comments
A*0258	HLA01610	2002-05-31	AY100700 AY100701	Sequence included in error

Information

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