IMGT/HLA Database

The HLA Dictionary

The IMGT/HLA Database allows you to retrieve information from the HLA Dictionary.

• R. Holdsworth, C.K. Hurley, S.G.E. Marsh, M. Lau, H.J. Noreen, J.H. Kempenich, M. Setterholm, M.Maiers:
  The HLA Dictionary 2008: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens
  Tissue Antigens (2009) 73:95-170
  Human Immunology (2009) in press
  
  The Full Text of the Tissue Antigens article is available from Wiley Interscience or you can download the PDF File.

The 2008 report of the human leukocyte antigen (HLA) data dictionary presents serologic equivalents of HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, and -DQB1 alleles. The dictionary is an update of the one published in 2004. The data summarize equivalents obtained by the World Health Organization Nomenclature Committee for Factors of the HLA System, the International Cell Exchange, UCLA, the National Marrow Donor Program, recent publications, and individual laboratories. The 2008 edition includes information on 832 new alleles (685 class I and 147 class II) and updated information on 766 previously listed alleles (577 class I and 189 class II). The tables list the alleles with remarks on the serologic patterns and the equivalents. The serological equivalents are listed as expert assigned types, and the data are useful for identifying potential stem cell donors who were typed by either serology or DNA-based methods.

How To Search the Dictionary

The search tool can be used to search for an allele, an expert assigned type of a WHO assigned type.

• To search for an entry for an allele name enter either the locus or the locus and up to four digits. (i.e.; A, A*01, A*0101)
• To search for an expert or WHO assigned type enter the serological type (i.e. A1, A2, A32), broad classifications will automatically be expanded (i.e. A28 will retrieve A68 and A69).

The search tool will then retrieve all relevant hits.

For a further explanation of the output form, click here.

Information

For more information about the database, IMGT/HLA queries (including website) or to subscribe to the IMGT/HLA mailing list please contact IMGT/HLA Support.