ID   FOSB_MOUSE     STANDARD;      PRT;   338 AA.
AC   P13346;
DT   01-JAN-1990 (Rel. 13, Created)
DT   01-JAN-1990 (Rel. 13, Last sequence update)
DT   15-JUN-2002 (Rel. 41, Last annotation update)
DE   Protein fosB.
GN   FOSB.
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=89251612; PubMed=2498083;
RA   Zerial M., Toschi L., Ryseck R.-P., Schuermann M., Mueller R.,
RA   Bravo R.;
RT   "The product of a novel growth factor activated gene, fos B, interacts
RT   with JUN proteins enhancing their DNA binding activity.";
RL   EMBO J. 8:805-813(1989).
RN   [2]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=92158623; PubMed=1741260;
RA   Lazo P.S., Dorfman K., Noguchi T., Mattei M.-G., Bravo R.;
RT   "Structure and mapping of the fosB gene. FosB downregulates the
RT   activity of the fosB promoter.";
RL   Nucleic Acids Res. 20:343-350(1992).
CC   -!- FUNCTION: FOSB INTERACTS WITH JUN PROTEINS ENHANCING THEIR DNA
CC       BINDING ACTIVITY.
CC   -!- SUBUNIT: HETERODIMER (BY SIMILARITY).
CC   -!- SUBCELLULAR LOCATION: NUCLEAR.
CC   -!- INDUCTION: BY GROWTH FACTORS.
CC   -!- SIMILARITY: BELONGS TO THE BZIP FAMILY. FOS SUBFAMILY.
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DR   EMBL; X14897; CAA33026.1; -.
DR   EMBL; AF093624; AAD13196.1; -.
DR   PIR; S04108; TVMSFB.
DR   PIR; S35477; S35477.
DR   HSSP; P01100; 1FOS.
DR   TRANSFAC; T00291; -.
DR   MGD; MGI:95575; Fosb.
DR   InterPro; IPR000837; Leuzip_Fos.
DR   InterPro; IPR004827; TF_bZIP.
DR   Pfam; PF00170; bZIP; 1.
DR   PRINTS; PR00042; LEUZIPPRFOS.
DR   SMART; SM00338; BRLZ; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
KW   Nuclear protein; DNA-binding.
FT   DNA_BIND    161    179       BASIC MOTIF.
FT   DOMAIN      183    211       LEUCINE-ZIPPER.
SQ   SEQUENCE   338 AA;  35976 MW;  E9D031A4BEAE48EC CRC64;
     MFQAFPGDYD SGSRCSSSPS AESQYLSSVD SFGSPPTAAA SQECAGLGEM PGSFVPTVTA
     ITTSQDLQWL VQPTLISSMA QSQGQPLASQ PPAVDPYDMP GTSYSTPGLS AYSTGGASGS
     GGPSTSTTTS GPVSARPARA RPRRPREETL TPEEEEKRRV RRERNKLAAA KCRNRRRELT
     DRLQAETDQL EEEKAELESE IAELQKEKER LEFVLVAHKP GCKIPYEEGP GPGPLAEVRD
     LPGSTSAKED GFGWLLPPPP PPPLPFQSSR DAPPNLTASL FTHSEVQVLG DPFPVVSPSY
     TSSFVLTCPE VSAFAGAQRT SGSEQPSDPL NSPSLLAL
//