Expression Atlas results for ENSMUSG00000059201

    Lep Mus musculus leptin
Orthologs OB (Bos taurus), LEP (Canis familiaris), lepa (Danio rerio), LEP (Equus caballus), LEP (Homo sapiens), LEP (Macaca mulatta), Lep (Rattus norvegicus), OB (Sus scrofa)
Gene Ontology negative regulation of transcription from RNA polymerase II promoter, ovulation from ovarian follicle, response to hypoxia, positive regulation of cytokine production, placenta development, regulation of protein phosphorylation, response to dietary excess, molecular function, protein binding, cellular component, extracellular region, extracellular space, intracellular, cell, cytoplasm, carbohydrate metabolic process, glucose metabolic process, regulation of gluconeogenesis, energy reserve metabolic process, glycerol biosynthetic process, cellular protein modification process, lipid metabolic process, fatty acid beta-oxidation, transport, signal transduction, tyrosine phosphorylation of STAT protein, cell-cell signaling, female pregnancy, response to nutrient, circadian rhythm, growth factor activity, biological process, cholesterol metabolic process, bile acid metabolic process, regulation of blood pressure, positive regulation of cell proliferation, adult feeding behavior, catabolic process, fatty acid catabolic process, negative regulation of metabolic process, regulation of metabolic process, central nervous system neuron development, insulin secretion, cell differentiation, regulation of intestinal cholesterol absorption, negative regulation of appetite, response to insulin, response to vitamin E, leptin-mediated signaling pathway, positive regulation of luteinizing hormone secretion, bone mineralization involved in bone maturation, positive regulation of protein import into nucleus, hormone metabolic process, positive regulation of tyrosine phosphorylation of Stat3 protein, homeostatic process, glucose homeostasis, eating behavior, negative regulation of apoptotic process, positive regulation of ion transport, positive regulation of MAPK cascade, small molecule metabolic process, regulation of fat cell differentiation, positive regulation of myeloid cell differentiation, negative regulation of vasoconstriction, positive regulation of JAK-STAT cascade, positive regulation of insulin receptor signaling pathway, positive regulation of follicle-stimulating hormone secretion, positive regulation of developmental growth, anatomical structure development, regulation of insulin secretion, regulation of steroid biosynthetic process, leukocyte tethering or rolling, peptide hormone receptor binding, regulation of lipoprotein lipid oxidation, adipose tissue development, negative regulation of cartilage development, negative regulation of glucagon secretion, cellular response to L-ascorbic acid, cellular response to retinoic acid, regulation of protein localization to nucleus, positive regulation of STAT protein import into nucleus, negative regulation of glutamine transport, positive regulation of hepatic stellate cell activation
InterPro Leptin (family), Four-helical cytokine-like, core (domain)
Ensembl Family LEPTIN OBESITY FACTOR
Ensembl Gene ENSMUSG00000059201
Entrez 16846
UniProt E9Q7Z0, P41160, Q544U0
EMAGE MGI:104663
MGI leptin
Gene Biotype protein_coding
Design Element 10536789, 1422582_at, 4345396, 4354272, 4504462, 4504780, 5413911, 5501225, 5591219, 98443_at, 98444_g_at, A_52_P374882, u18812_s_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 7 results
Showing 7 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0