Expression Atlas results for ENSMUSG00000042258

    Isl1 Mus musculus ISL1 transcription factor, LIM/homeodomain
Synonyms Islet 1
Orthologs ISL1 (Bos taurus), ISL1 (Canis familiaris), ENSCING00000000421 (Ciona intestinalis), ENSCSAVG00000008352 (Ciona savignyi), isl1 (Danio rerio), ISL1 (Equus caballus), ISL1 (Homo sapiens), ISL1 (Gallus gallus), ISL1 (Macaca mulatta), Isl1 (Rattus norvegicus), ISL1 (Sus scrofa), isl1 (Xenopus tropicalis), tup (Drosophila melanogaster), lim-7 (Caenorhabditis elegans)
Gene Ontology negative regulation of transcription from RNA polymerase II promoter, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, enhancer sequence-specific DNA binding, neural crest cell migration, heart morphogenesis, secondary heart field specification, outflow tract septum morphogenesis, outflow tract morphogenesis, endocardial cushion morphogenesis, cardiac right ventricle morphogenesis, regulation of secondary heart field cardioblast proliferation, DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, protein binding, intracellular, nucleus, regulation of transcription, DNA-templated, heart development, zinc ion binding, positive regulation of cell proliferation, regulation of gene expression, positive regulation vascular endothelial growth factor production, ligand-dependent nuclear receptor binding, spinal cord motor neuron cell fate specification, spinal cord motor neuron differentiation, visceral motor neuron differentiation, trigeminal nerve development, pituitary gland development, neuron differentiation, estrogen receptor binding, pancreas development, axon regeneration, retinal ganglion cell axon guidance, positive regulation of insulin secretion, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of interferon-gamma production, positive regulation of interleukin-1 alpha production, positive regulation of interleukin-1 beta production, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of tumor necrosis factor production, negative regulation of intracellular estrogen receptor signaling pathway, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of DNA binding, bHLH transcription factor binding, negative regulation of neuron apoptotic process, sequence-specific DNA binding, negative regulation of neuron differentiation, positive regulation of angiogenesis, negative regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, neuron fate commitment, neuron fate specification, mesenchymal cell differentiation, sensory system development, peripheral nervous system neuron development, peripheral nervous system neuron axonogenesis, negative regulation of inflammatory response, ventricular cardiac muscle tissue morphogenesis, pharyngeal system development, cardiac muscle cell myoblast differentiation, innervation, atrial septum morphogenesis, cardiac cell fate determination, cellular response to glucocorticoid stimulus, positive regulation of granulocyte colony-stimulating factor production, negative regulation of protein homodimerization activity, negative regulation of canonical Wnt signaling pathway, positive regulation of macrophage colony-stimulating factor production
InterPro Homeobox domain (domain), Zinc finger, LIM-type (domain), Homeodomain-like (domain)
Ensembl Family INSULIN GENE ENHANCER ISL ISLET
Ensembl Gene ENSMUSG00000042258
Entrez 16392
UniProt A2RSV5, P61372
EMAGE MGI:101791
MGI ISL1 transcription factor, LIM/homeodomain
Gene Biotype protein_coding
Design Element 10412335, 134273_at, 1422720_at, 1450723_at, 4309948, 4432054, 4453108, 4482825, 4519119, 4564242, 4863293, 4980112, 4993667, 5063364, 5144833, 5208705, 5354209, 5360116, 5555618, 92515_at, A_52_P337246
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 8 results
Showing 8 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0