Expression Atlas results for ENSMUSG00000039005

    Tlr4 Mus musculus toll-like receptor 4
Synonyms Lps, Rasl2-8, lipopolysaccharide response
Orthologs TLR4 (Bos taurus), TLR4 (Canis familiaris), ci-tlr2 (Ciona intestinalis), tlr4ba (Danio rerio), tlr4bb (Danio rerio), tlr4al (Danio rerio), TLR4 (Equus caballus), TLR4 (Homo sapiens), TLR4 (Gallus gallus), TLR4 (Macaca mulatta), Tlr4 (Rattus norvegicus), TLR4 (Sus scrofa), ENSSSCG00000024231
Gene Ontology activation of MAPK activity, lipopolysaccharide receptor activity, activation of innate immune response, toll-like receptor signaling pathway, B cell proliferation involved in immune response, nitric oxide production involved in inflammatory response, MyD88-dependent toll-like receptor signaling pathway, transmembrane signaling receptor activity, protein binding, cytoplasm, plasma membrane, integral component of plasma membrane, immune response, signal transduction, activation of NF-kappaB-inducing kinase activity, I-kappaB phosphorylation, response to bacterium, external side of plasma membrane, positive regulation of platelet activation, integral component of membrane, positive regulation of B cell proliferation, lipopolysaccharide-mediated signaling pathway, response to lipopolysaccharide, detection of lipopolysaccharide, interferon-gamma production, negative regulation of interferon-gamma production, negative regulation of interleukin-17 production, negative regulation of interleukin-23 production, negative regulation of interleukin-6 production, negative regulation of tumor necrosis factor production, positive regulation of chemokine production, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of interferon-gamma production, positive regulation of interleukin-1 production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of tumor necrosis factor production, positive regulation of stress-activated MAPK cascade, toll-like receptor 4 signaling pathway, macrophage activation, positive regulation of NF-kappaB import into nucleus, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of interleukin-12 biosynthetic process, innate immune response, positive regulation of MHC class II biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interleukin-1 biosynthetic process, positive regulation of interleukin-13 biosynthetic process, positive regulation of interleukin-6 biosynthetic process, positive regulation of interleukin-8 biosynthetic process, positive regulation of nitric oxide biosynthetic process, mast cell activation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of JNK cascade, lipopolysaccharide receptor complex, perinuclear region of cytoplasm, positive regulation of lymphocyte proliferation, regulation of cytokine secretion, regulation of inflammatory response, defense response to Gram-negative bacterium, positive regulation of NF-kappaB transcription factor activity, positive regulation of nitric-oxide synthase biosynthetic process, intestinal epithelial structure maintenance, positive regulation of macrophage cytokine production, negative regulation of ERK1 and ERK2 cascade, positive regulation of ERK1 and ERK2 cascade, positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway, positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to mechanical stimulus
InterPro Toll/interleukin-1 receptor homology (TIR) domain (domain), Cysteine-rich flanking region, C-terminal (domain), Leucine-rich repeat (repeat), Leucine-rich repeat, typical subtype (repeat), Toll-like receptor (family)
Ensembl Family TOLL RECEPTOR 4 PRECURSOR CD284 ANTIGEN
Ensembl Gene ENSMUSG00000039005
Entrez 21898
UniProt A2BHU8, L0CL36, Q9QUK6
EMAGE MGI:96824
MGI toll-like receptor 4
Gene Biotype protein_coding
Design Element 10505517, 111295_at, 1418162_at, 1418163_at, 1430695_at, 1442827_at, 4369462, 4376441, 4877727, 5073811, 5146110, 5187226, 5289992, 5330602, 5535590, 5572692, A_52_P24230, A_55_P2076390, A_66_P124806
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 14 results
Showing 14 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0