Expression Atlas results for ENSMUSG00000036273

    Lrrk2 Mus musculus leucine-rich repeat kinase 2
Synonyms 4921513O20Rik, 9330188B09Rik, D630001M17Rik, LOC381026, cI-46
Orthologs LRRK2 (Bos taurus), LRRK2 (Canis familiaris), ENSCING00000011837 (Ciona intestinalis), LRRK2 (1 of 2) (Danio rerio), LRRK2 (2 of 2) (Danio rerio), LRRK2 (Equus caballus), LRRK2 (Homo sapiens), LRRK2 (Gallus gallus), LRRK2 (Macaca mulatta), Lrrk2 (Rattus norvegicus), LRRK2 (Sus scrofa), lrrk2 (Xenopus tropicalis), Lrrk (Drosophila melanogaster), lrk-1 (Caenorhabditis elegans)
Gene Ontology SNARE binding, MAPK cascade, activation of MAPKK activity, activation of MAPK activity, cell morphogenesis, negative regulation of protein phosphorylation, positive regulation of protein phosphorylation, glycoprotein binding, molecular function, actin binding, GTPase activity, protein serine/threonine kinase activity, MAP kinase kinase activity, GTPase activator activity, protein binding, ATP binding, GTP binding, cellular component, extracellular space, intracellular, cell, cytoplasm, mitochondrion, mitochondrial outer membrane, mitochondrial inner membrane, mitochondrial matrix, lysosome, endosome, vacuole, endoplasmic reticulum, Golgi apparatus, trans-Golgi network, cytosol, plasma membrane, GTP catabolic process, cellular protein modification process, protein phosphorylation, transport, endocytosis, autophagy, response to oxidative stress, signal transduction, small GTPase mediated signal transduction, cell-cell signaling, neuromuscular junction development, synaptic vesicle, biological process, determination of adult lifespan, catabolic process, positive regulation of autophagy, regulation of protein kinase A signaling, negative regulation of protein processing, regulation of neuron maturation, tubulin binding, membrane, cytoplasmic membrane-bounded vesicle, vesicle-mediated transport, inclusion body, kinase activity, Rho GTPase binding, syntaxin-1 binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, enzyme binding, olfactory bulb development, tangential migration from the subventricular zone to the olfactory bulb, cell differentiation, clathrin binding, axon, dendrite, positive regulation of protein ubiquitination, cytoplasmic vesicle, mitochondrial membrane, negative regulation of protein binding, positive regulation of protein binding, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, cytoplasmic side of mitochondrial outer membrane, dendrite cytoplasm, GTP-dependent protein kinase activity, negative regulation of GTPase activity, cellular response to oxidative stress, cellular protein localization, intracellular signal transduction, regulation of kidney size, exploration behavior, locomotory exploration behavior, synaptic vesicle recycling, regulation of locomotion, regulation of membrane potential, identical protein binding, protein homodimerization activity, neuron projection, neuronal cell body, positive regulation of programmed cell death, ion binding, terminal bouton, perikaryon, organelle, intracellular membrane-bounded organelle, positive regulation of GTPase activity, ion channel binding, membrane raft, synapse, protein autophosphorylation, intracellular distribution of mitochondria, neuron projection morphogenesis, anatomical structure development, protein kinase A binding, regulation of mitochondrial depolarization, regulation of synaptic transmission, glutamatergic, regulation of excitatory postsynaptic membrane potential, regulation of dopamine receptor signaling pathway, positive regulation of dopamine receptor signaling pathway, regulation of dendritic spine morphogenesis, extracellular vesicular exosome, neuron death, cellular response to manganese ion, cellular response to organic cyclic compound, reactive oxygen species metabolic process, regulation of neuron death, positive regulation of protein autoubiquitination, regulation of neuroblast proliferation, regulation of synaptic vesicle transport, negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation, regulation of branching morphogenesis of a nerve, regulation of synaptic vesicle exocytosis, negative regulation of peroxidase activity
InterPro Protein kinase domain (domain), Serine-threonine/tyrosine-protein kinase catalytic domain (domain), Leucine-rich repeat (repeat), Small GTPase superfamily (family), Serine/threonine/dual specificity protein kinase, catalytic domain (domain), Small GTPase superfamily, Rab type (family), Leucine-rich repeat, typical subtype (repeat), Small GTP-binding protein domain (domain), Protein kinase-like domain (domain), Mitochondrial Rho-like (domain), Armadillo-type fold (domain), WD40-repeat-containing domain (domain), Tyrosine-protein kinase, catalytic domain (domain), P-loop containing nucleoside triphosphate hydrolase (domain)
Ensembl Family LEUCINE RICH REPEAT SERINE/THREONINE KINASE 2 EC_2.7.11.1
Ensembl Gene ENSMUSG00000036273
Entrez 66725
UniProt Q5S006
EMAGE MGI:1913975
MGI leucine-rich repeat kinase 2
Gene Biotype protein_coding
Design Element 10426315, 1431394_a_at, 166783_r_at, 4306404;, 4307678;, 4310929;, 4317250;, 4323692;, 4354935;, 4360405;, 4367378;, 4369841;, 4396428;, 4417780;, 4423292;, 4428652;, 4432417;, 4439642;, 4460052;, 4473386;, 4499934;, 4505870;, 4524970;, 4547393;, 4551695;, 4586081;, 4593777;, 4605868;, 4609653;, 4627934;, 4640579;, 4643886;, 4663539;, 4707673;, 4766610;, 4781049;, 4786388;, 4810909;, 4815507;, 4928530;, 4936270;, 4944705;, 4970413;, 4985246;, 4986534;, 5003534;, 5014442;, 5025040;, 5041195;, 5046318;, 5084742;, 5118751;, 5121381;, 5132709;, 5132880;, 5158105;, 5163536;, 5188612;, 5210932;, 5238254;, 5247542;, 5273500;, 5277233;, 5278268;, 5284716;, 5288897;, 5290915;, 5309651;, 5342200;, 5364708;, 5375734;, 5383933;, 5393679;, 5399747;, 5403763;, 5440676;, 5454499;, 5506198;, 5522182;, 5530425;, 5604856;, A_51_P290788, A_55_P1984406, A_66_P101538
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 15 results
Showing 15 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0