Expression Atlas results for ENSMUSG00000026923

    Notch1 Mus musculus notch 1
Synonyms Mis6, Motch A, N1, Tan1, lin-12
Orthologs NOTCH1 (Bos taurus), NOTCH1 (Canis familiaris), n (Ciona intestinalis), ENSCSAVG00000000533 (Ciona savignyi), notch1a (Danio rerio), notch1b (Danio rerio), NOTCH1 (Equus caballus), NOTCH1 (Homo sapiens), NOTCH1 (Gallus gallus), NOTCH1 (Macaca mulatta), Notch1 (Rattus norvegicus), notch1 (Xenopus tropicalis), N (Drosophila melanogaster), crb-1 (Caenorhabditis elegans)
Gene Ontology negative regulation of transcription from RNA polymerase II promoter, Golgi membrane, core promoter binding, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, in utero embryonic development, cell fate specification, ruffle, epithelial to mesenchymal transition, liver development, heart looping, sprouting angiogenesis, osteoblast fate commitment, MAML1-RBP-Jkappa- ICN1 complex, inflammatory response to antigenic stimulus, endocardium development, endocardium morphogenesis, atrioventricular node development, coronary vein morphogenesis, aortic valve morphogenesis, atrioventricular valve morphogenesis, pulmonary valve morphogenesis, mitral valve formation, epithelial to mesenchymal transition involved in endocardial cushion formation, endocardial cushion morphogenesis, cardiac chamber formation, cardiac ventricle morphogenesis, cardiac atrium morphogenesis, cardiac right atrium morphogenesis, cardiac left ventricle morphogenesis, cardiac right ventricle formation, ventricular trabecula myocardium morphogenesis, growth involved in heart morphogenesis, regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation, cell migration involved in endocardial cushion formation, pericardium morphogenesis, chromatin binding, sequence-specific DNA binding transcription factor activity, enzyme inhibitor activity, receptor activity, calcium ion binding, protein binding, extracellular region, nucleus, nucleoplasm, cytoplasm, endoplasmic reticulum membrane, cytosol, cytoskeleton, plasma membrane, integral component of plasma membrane, transcription, DNA-templated, regulation of transcription from RNA polymerase II promoter, humoral immune response, Notch signaling pathway, positive regulation of transcription of Notch receptor target, multicellular organismal development, determination of left/right symmetry, compartment pattern specification, axonogenesis, foregut morphogenesis, endoderm development, heart development, positive regulation of cell proliferation, negative regulation of cell proliferation, epidermis development, auditory receptor cell fate commitment, cell surface, glial cell differentiation, regulation of gene expression, positive regulation of epithelial to mesenchymal transition, negative regulation of cell-substrate adhesion, negative regulation of myotube differentiation, mesenchymal cell development, regulation of somitogenesis, membrane, integral component of membrane, enzyme binding, neural tube development, lamellipodium, cell differentiation, neuron differentiation, keratinocyte differentiation, negative regulation of ossification, lung development, embryonic limb morphogenesis, regulation of cell migration, positive regulation of cell migration, positive regulation of BMP signaling pathway, negative regulation of BMP signaling pathway, forebrain development, hair follicle morphogenesis, chromatin DNA binding, response to muramyl dipeptide, embryonic hindlimb morphogenesis, tube formation, skeletal muscle cell differentiation, cellular response to vascular endothelial growth factor stimulus, anagen, positive regulation of apoptotic process, negative regulation of catalytic activity, receptor complex, sequence-specific DNA binding, cell fate commitment, negative regulation of cell differentiation, positive regulation of keratinocyte differentiation, negative regulation of myoblast differentiation, negative regulation of neuron differentiation, negative regulation of osteoblast differentiation, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, negative regulation of calcium ion-dependent exocytosis, positive regulation of JAK-STAT cascade, negative regulation of photoreceptor cell differentiation, somatic stem cell division, neuron fate commitment, positive regulation of astrocyte differentiation, negative regulation of oligodendrocyte differentiation, branching morphogenesis of an epithelial tube, regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation, regulation of neurogenesis, negative regulation of neurogenesis, regulation of developmental process, cardiac muscle tissue morphogenesis, cardiac muscle cell proliferation, positive regulation of cardiac muscle cell proliferation, negative regulation of glial cell proliferation, cilium morphogenesis, cardiac epithelial to mesenchymal transition, cardiac septum morphogenesis, ventricular septum morphogenesis, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, negative regulation of cell death, prostate gland epithelium morphogenesis, regulation of epithelial cell proliferation involved in prostate gland development, arterial endothelial cell differentiation, venous endothelial cell differentiation, cardiac vascular smooth muscle cell development, endocardial cell differentiation, vasculogenesis involved in coronary vascular morphogenesis, coronary artery morphogenesis, Notch signaling involved in heart development, regulation of cell adhesion involved in heart morphogenesis, heart trabecula morphogenesis, positive regulation of transcription from RNA polymerase II promoter in response to hypoxia, left/right axis specification, cellular response to follicle-stimulating hormone stimulus, cell periphery, distal tubule development, collecting duct development, glomerular mesangial cell development, interleukin-4 secretion, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of canonical Wnt signaling pathway, neuronal stem cell maintenance, positive regulation of ephrin receptor signaling pathway, regulation of extracellular matrix assembly, apoptotic process involved in embryonic digit morphogenesis, negative regulation of stem cell differentiation, negative regulation of anoikis, negative regulation of pro-B cell differentiation, negative regulation of endothelial cell chemotaxis
InterPro Epidermal growth factor-like domain (domain), Notch domain (domain), EGF-like calcium-binding domain (domain), Ankyrin repeat (repeat), Notch (family), Notch, NOD domain (domain), Notch, NODP domain (domain), EGF-like domain, extracellular (domain), Ankyrin repeat-containing domain (domain), Neurogenic locus Notch 4 (family), Neurogenic locus Notch 1 (family), Domain of unknown function DUF3454, notch (domain)
Ensembl Family NEUROGENIC LOCUS NOTCH HOMOLOG 1 FRAGMENT, NEUROGENIC LOCUS NOTCH HOMOLOG PRECURSOR NOTCH [CONTAINS NOTCH EXTRACELLULAR NOTCH INTRACELLULAR
Ensembl Gene ENSMUSG00000026923
Entrez 18128
UniProt A2AIX5, Q01705, Q8BY39
EMAGE MGI:97363
MGI notch 1
Gene Biotype protein_coding
Design Element 10481056, 1418633_at, 1418634_at, 4365588, 4372931, 4408421, 4450668, 4489003, 4512011, 4521824, 4562330, 4631515, 4638694, 4640328, 4643515, 4659863, 4669270, 4708475, 4718004, 4719480, 4749725, 4755982, 4761524, 4805823, 4845090, 4866911, 4894877, 4911093, 4934863, 4944026, 4985018, 4985275, 4998309, 5044444, 5046350, 5087908, 5111730, 5111854, 5118109, 5159085, 5168546, 5171277, 5227476, 5236249, 5239017, 5288172, 5289006, 5304448, 5365326, 5407427, 5424548, 5485913, 5534440, 5551381, 5555601, 5578989, 5584533, 5586271, 97497_at, A_52_P183088, A_55_P2047168, A_55_P2171897, Z11886_s_at, aa271199_s_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 14 results
Showing 14 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0