Expression Atlas results for ENSMUSG00000024401

    Tnf Mus musculus tumor necrosis factor
Synonyms DIF, TNF alpha, TNF-alpha, TNFalpha, Tnfa, Tnfsf1a, tumor necrosis factor-alpha
Orthologs TNF (Bos taurus), TNF (Canis familiaris), tnfa (Danio rerio), tnfb (Danio rerio), TNF (Equus caballus), TNF (Homo sapiens), TNF (Macaca mulatta), Tnf (Rattus norvegicus), TNFA (Sus scrofa), tnf (Xenopus tropicalis)
Gene Ontology protein import into nucleus, translocation, negative regulation of transcription from RNA polymerase II promoter, MAPK cascade, activation of MAPKKK activity, activation of MAPK activity, response to hypoxia, cell activation, positive regulation of cytokine production, phagocytic cup, regulation of protein phosphorylation, positive regulation of protein phosphorylation, protease binding, negative regulation of L-glutamate transport, immune system process, chronic inflammatory response to antigenic stimulus, negative regulation of cytokine secretion involved in immune response, positive regulation of chronic inflammatory response to antigenic stimulus, positive regulation of humoral immune response mediated by circulating immunoglobulin, skeletal muscle contraction, molecular function, cytokine activity, tumor necrosis factor receptor binding, protein binding, cellular component, extracellular region, extracellular space, intracellular, cell, cytoplasm, endosome, plasma membrane, integral component of plasma membrane, carbohydrate metabolic process, glucose metabolic process, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process, transformed cell apoptotic process, response to stress, defense response, inflammatory response, humoral immune response, signal transduction, JNK cascade, multicellular organismal development, biological process, cell death, cell proliferation, positive regulation of cell proliferation, negative regulation of cell proliferation, extrinsic apoptotic signaling pathway via death domain receptors, intrinsic apoptotic signaling pathway in response to DNA damage, response to radiation, response to mechanical stimulus, response to virus, organ morphogenesis, external side of plasma membrane, cell surface, positive regulation of gene expression, negative regulation of gene expression, negative regulation of alkaline phosphatase activity, response to activity, integral component of membrane, cytoplasmic membrane-bounded vesicle, calcium-mediated signaling, enzyme binding, secretory granule, cell differentiation, extracellular matrix organization, osteoclast differentiation, sequestering of triglyceride, positive regulation of protein complex assembly, positive regulation of fever generation, lipopolysaccharide-mediated signaling pathway, response to lipopolysaccharide, negative regulation of interleukin-6 production, positive regulation of chemokine production, positive regulation of interferon-gamma production, positive regulation of interleukin-18 production, positive regulation of interleukin-6 production, receptor biosynthetic process, positive regulation of peptidyl-serine phosphorylation, tumor necrosis factor-mediated signaling pathway, positive regulation of heterotypic cell-cell adhesion, locomotion, regulation of cell proliferation, positive regulation of NF-kappaB import into nucleus, response to drug, defense response to bacterium, identical protein binding, positive regulation of apoptotic process, positive regulation of programmed cell death, regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of I-kappaB kinase/NF-kappaB signaling, organelle, negative regulation of protein complex disassembly, positive regulation of protein complex disassembly, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of MAP kinase activity, protein kinase B signaling, positive regulation of JUN kinase activity, positive regulation of neuron apoptotic process, negative regulation of growth of symbiont in host, transcription regulatory region DNA binding, negative regulation of viral genome replication, positive regulation of chemokine biosynthetic process, membrane raft, cellular extravasation, positive regulation of interleukin-8 biosynthetic process, positive regulation of nitric oxide biosynthetic process, negative regulation of myoblast differentiation, negative regulation of osteoblast differentiation, regulation of osteoclast differentiation, positive regulation of osteoclast differentiation, positive regulation of action potential, positive regulation of mitosis, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translational initiation by iron, negative regulation of glucose import, positive regulation of JNK cascade, embryonic digestive tract development, positive regulation of smooth muscle cell proliferation, anatomical structure development, cell motility, regulation of protein secretion, positive regulation of cytokine secretion, positive regulation of inflammatory response, regulation of insulin secretion, positive regulation of synaptic transmission, defense response to Gram-positive bacterium, leukocyte migration, leukocyte tethering or rolling, detection of mechanical stimulus involved in sensory perception of pain, negative regulation of lipid catabolic process, regulation of immunoglobulin secretion, positive regulation of membrane protein ectodomain proteolysis, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of protein transport, response to glucocorticoid, positive regulation of NFAT protein import into nucleus, protein maturation, positive regulation of hair follicle development, positive regulation of protein kinase B signaling, recycling endosome, positive regulation of vitamin D biosynthetic process, positive regulation of calcidiol 1-monooxygenase activity, epithelial cell proliferation involved in salivary gland morphogenesis, regulation of branching involved in salivary gland morphogenesis, negative regulation of branching involved in lung morphogenesis, cellular response to lipopolysaccharide, cellular response to amino acid stimulus, cellular response to nicotine, cellular response to organic cyclic compound, positive regulation of podosome assembly, apoptotic signaling pathway, extrinsic apoptotic signaling pathway, necroptotic signaling pathway, response to gold nanoparticle, positive regulation of protein localization to cell surface, positive regulation of chemokine (C-X-C motif) ligand 2 production, regulation of reactive oxygen species metabolic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
InterPro Tumour necrosis factor alpha (family), Tumour necrosis factor domain (domain), Tumour necrosis factor (family), Tumour necrosis factor-like domain (domain)
Ensembl Family TUMOR NECROSIS FACTOR PRECURSOR CACHECTIN TNF ALPHA TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 2 TNF A [CONTAINS TUMOR NECROSIS FACTOR MEMBRANE FORM N TERMINAL FRAGMENT NTF ; INTRACELLULAR DOMAIN 1 ICD1 ; INTRACELLULAR DOMAIN 2 ICD2 ; C DOMAIN 1; C D
Ensembl Gene ENSMUSG00000024401
Entrez 21926
UniProt P06804, Q0X0E6, Q3U593, Q6TDG3
EMAGE MGI:104798
MGI tumor necrosis factor
Gene Biotype protein_coding
Design Element 102629_at, 10450501, 1419607_at, 4556801;, 4649181;, 5106210;, 5176196;, 5453021;, 5558978;, A_51_P385099, TNFa_at, x02611_s_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 10 results
Showing 10 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0