Expression Atlas results for ENSMUSG00000023826

    Park2 Mus musculus Parkinson disease (autosomal recessive, juvenile) 2, parkin
Synonyms PRKN
Orthologs PARK2 (Bos taurus), ENSCAFG00000000769 (Canis familiaris), ENSCAFG00000032456 (Canis familiaris), park2 (Danio rerio), PARK2 (Equus caballus), PARK2 (Homo sapiens), PARK2 (Gallus gallus), PARK2 (Macaca mulatta), Park2 (Rattus norvegicus), PARK2 (Sus scrofa), ENSSSCG00000026205 (Sus scrofa), park (Drosophila melanogaster), pdr-1 (Caenorhabditis elegans)
Gene Ontology ubiquitin ligase complex, protein polyubiquitination, mitochondrial fission, mitochondrion degradation, G-protein coupled receptor binding, negative regulation of protein phosphorylation, synaptic transmission, dopaminergic, startle response, molecular function, ubiquitin-protein transferase activity, protein binding, cellular component, intracellular, cell, nucleus, cytoplasm, mitochondrion, endoplasmic reticulum, Golgi apparatus, cytosol, plasma membrane, transcription, DNA-templated, regulation of transcription, DNA-templated, cellular protein modification process, protein monoubiquitination, transport, response to stress, response to oxidative stress, mitochondrion organization, cell-cell signaling, learning, locomotory behavior, biological process, zinc ion binding, adult locomotory behavior, catabolic process, biosynthetic process, regulation of autophagy, positive regulation of mitochondrial fusion, negative regulation of mitochondrial fusion, regulation of mitochondrion organization, aggresome, protein ubiquitination, ligase activity, protein metabolic process, kinase binding, protein kinase binding, cell junction, PDZ domain binding, Hsp70 protein binding, heat shock protein binding, ubiquitin conjugating enzyme binding, ubiquitin protein ligase binding, small conjugating protein binding, negative regulation of actin filament bundle assembly, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of glucokinase activity, cellular nitrogen compound metabolic process, response to endoplasmic reticulum stress, synaptic transmission, glutamatergic, norepinephrine metabolic process, dopamine metabolic process, homeostatic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, identical protein binding, neuron projection, positive regulation of I-kappaB kinase/NF-kappaB signaling, ubiquitin binding, proteasome-mediated ubiquitin-dependent protein catabolic process, ion binding, organelle, protein complex, positive regulation of DNA binding, negative regulation of neuron apoptotic process, cellular protein catabolic process, postsynaptic membrane, positive regulation of transcription from RNA polymerase II promoter, negative regulation of JNK cascade, negative regulation of insulin secretion, regulation of neurotransmitter secretion, perinuclear region of cytoplasm, regulation of synaptic transmission, neurological system process, chaperone binding, dopamine uptake involved in synaptic transmission, protein autoubiquitination, zinc ion homeostasis, negative regulation of cell death, ubiquitin protein ligase activity, neuron cellular homeostasis, protein K63-linked ubiquitination, protein localization to mitochondrion, aggresome assembly, protein K48-linked ubiquitination, LUBAC complex, positive regulation of mitochondrial fission, negative regulation of release of cytochrome c from mitochondria, cellular response to toxic substance, cullin family protein binding, regulation of cellular response to oxidative stress, negative regulation of neuron death, positive regulation of proteasomal protein catabolic process, negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, positive regulation of protein linear polyubiquitination, ubiquitin-specific protease binding, regulation of reactive oxygen species metabolic process, negative regulation of reactive oxygen species metabolic process
InterPro Ubiquitin-like (domain), Zinc finger, C6HC-type (domain), E3 ubiquitin-protein ligase parkin (family), Ubiquitin (family), Rad60/SUMO-like domain (domain), Ubiquitin-related domain (domain)
Ensembl Family E3 UBIQUITIN LIGASE PARKIN EC_6.3.2.-, UNKNOWN
Ensembl Gene ENSMUSG00000023826
Entrez 50873
UniProt F6TNF2, Q7TPF7, Q7TPF8, Q8K1N5, Q9WVS6
EMAGE MGI:1355296
MGI Parkinson disease (autosomal recessive, juvenile) 2, parkin
Gene Biotype protein_coding
Design Element 102073_at, 10441718, 140452_at, 140453_g_at, 1420755_a_at, 1426135_a_at, 1449975_a_at, 4313039, 4326650, 4326707, 4334955, 4335349, 4342637, 4394165, 4452040, 4460959, 4479899, 4499001, 4576702, 4583915, 4607727, 4607877, 4644097, 4716013, 4751870, 4865465, 4943206, 5031918, 5050779, 5127518, 5154000, 5252416, 5307034, 5432580, 5480781, 5515070, 5573744, A_52_P327073, A_52_P342940, A_52_P636038, A_55_P1978226, A_55_P2055379
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 2 results
Showing 2 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0