Expression Atlas results for ENSMUSG00000022623

    Shank3 Mus musculus SH3/ankyrin domain gene 3
Synonyms ProSAP2
Orthologs ENSBTAG00000030180 (Bos taurus), ENSCAFG00000029677 (Canis familiaris), ENSCAFG00000032311 (Canis familiaris), ENSCING00000010709, CU681836.2 (Danio rerio), ENSECAG00000011905 (Equus caballus), ENSGALG00000026110 (Gallus gallus), SHANK3 (Macaca mulatta), ENSMMUG00000005588 (Macaca mulatta), Shank3 (Rattus norvegicus), ENSSSCG00000021269, shank3 (Xenopus tropicalis), Prosap (Drosophila melanogaster), shn-1 (Caenorhabditis elegans)
Gene Ontology MAPK cascade, embryonic epithelial tube formation, actin binding, protein binding, cytoplasm, plasma membrane, synapse assembly, learning, memory, protein C-terminus binding, zinc ion binding, postsynaptic density, SH3 domain binding, striatal medium spiny neuron differentiation, cell junction, GKAP/Homer scaffold activity, negative regulation of actin filament bundle assembly, social behavior, ionotropic glutamate receptor binding, locomotory exploration behavior, identical protein binding, neuron projection, dendritic spine, protein self-association, neuron spine, synapse, postsynaptic membrane, negative regulation of cell volume, positive regulation of long-term neuronal synaptic plasticity, brain morphogenesis, neuromuscular process controlling balance, protein oligomerization, positive regulation of synapse structural plasticity, positive regulation of synaptic transmission, glutamatergic, excitatory synapse, ciliary membrane, dendritic spine morphogenesis, positive regulation of dendritic spine development, regulation of dendritic spine morphogenesis, vocalization behavior, postsynaptic density assembly, scaffold protein binding, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering, N-methyl-D-aspartate receptor clustering, guanylate kinase-associated protein clustering, neuronal postsynaptic density, regulation of long-term synaptic potentiation, positive regulation of glutamate receptor signaling pathway, regulation of long term synaptic depression, positive regulation of excitatory postsynaptic membrane potential, regulation of grooming behavior, regulation of behavioral fear response, positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
InterPro SH3 domain (domain), PDZ domain (domain), Sterile alpha motif domain (domain), Ankyrin repeat (repeat), Sterile alpha motif, type 2 (domain), Variant SH3 domain (domain), Sterile alpha motif/pointed domain (domain), Ankyrin repeat-containing domain (domain), Sterile alpha motif, type 1 (domain)
Ensembl Family SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROLINE RICH SYNAPSE ASSOCIATED
Ensembl Gene ENSMUSG00000022623
Entrez 58234
UniProt E9Q1P5, F8S0X7, Q4ACU6
EMAGE MGI:1930016
MGI SH3/ankyrin domain gene 3
Gene Biotype protein_coding
Design Element 10426261, 105820_at, 105954_at, 1419137_at, 4375493, 4401710, 4428518, 4475606, 4504392, 4554535, 4576763, 4597627, 4606778, 4647349, 4649795, 4657132, 4684471, 4770302, 4811551, 4812103, 4812454, 4816126, 4825047, 4837747, 4856142, 4877754, 4897702, 4965349, 4965605, 4987548, 5081072, 5109679, 5140466, 5233661, 5235327, 5249382, 5254971, 5357276, 5370664, 5458254, 5565681, A_51_P115626, A_55_P2089858
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 8 results
Showing 8 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0