Expression Atlas results for ENSMUSG00000021313

    Ryr2 Mus musculus ryanodine receptor 2, cardiac
Orthologs RYR2 (Bos taurus), RYR2 (Canis familiaris), CABZ01065506.1 (Danio rerio), ryr2a (Danio rerio), RYR2 (Equus caballus), RYR2 (Homo sapiens), RYR2 (Gallus gallus), RYR2 (Macaca mulatta), Ryr2 (Rattus norvegicus), RYR2 (Sus scrofa)
Gene Ontology BMP signaling pathway, DNA binding, Purkinje myocyte to ventricular cardiac muscle cell signaling, Z disc, binding, calcium channel activity, calcium channel complex, calcium ion binding, calcium ion transmembrane transport, calcium ion transport, calcium ion transport into cytosol, calcium-induced calcium release activity, calcium-mediated signaling, calcium-mediated signaling using intracellular calcium source, calcium-release channel activity, calmodulin binding, canonical Wnt signaling pathway, cardiac muscle contraction, cardiac muscle hypertrophy, cellular calcium ion homeostasis, cellular response to caffeine, cytosolic calcium ion transport, detection of calcium ion, embryonic heart tube morphogenesis, enzyme binding, establishment of protein localization to endoplasmic reticulum, identical protein binding, integral to membrane, intracellular ligand-gated calcium channel activity, ion channel activity, ion transport, left ventricular cardiac muscle tissue morphogenesis, membrane, positive regulation of calcium-transporting ATPase activity, positive regulation of heart rate, positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction, positive regulation of sequestering of calcium ion, protein binding, protein complex, protein kinase A catalytic subunit binding, protein kinase A regulatory subunit binding, protein kinase binding, protein self-association, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of transcription, DNA-dependent, regulation of ventricular cardiac muscle cell action potential, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to caffeine, response to hypoxia, response to redox state, ryanodine-sensitive calcium-release channel activity, sarcomere, sarcoplasmic reticulum, sarcoplasmic reticulum membrane, suramin binding, transmembrane transport, type B pancreatic cell apoptotic process
InterPro B30.2/SPRY domain, Concanavalin A-like lectin/glucanases superfamily, EF-hand domain, Inositol 1,4,5-trisphosphate/ryanodine receptor, Intracellular calcium-release channel, Ion transport domain, MIR motif, RyR/IP3R Homology associated domain, Ryanodine Receptor TM 4-6, Ryanodine receptor, Ryanodine receptor Ryr, SPla/RYanodine receptor SPRY, SPla/RYanodine receptor subgroup, Signal transduction response regulator, C-terminal effector
Ensembl Family RYANODINE RECEPTOR RYR MUSCLE CALCIUM RELEASE CHANNEL MUSCLE TYPE RYANODINE RECEPTOR TYPE RYANODINE RECEPTOR
Ensembl Gene ENSMUSG00000021313
Entrez 20191
UniProt E9Q401, F6U7V1, Q9CTT8
EMAGE MGI:99685
MGI ryanodine receptor 2, cardiac
Gene Biotype protein_coding
Design Element 102653_at, 10407598, 1421126_at, 1450123_at, 4322757, 4325565, 4326165, 4328468, 4363684, 4366944, 4390463, 4433473, 4447412, 4468994, 4470003, 4470923, 4473595, 4480170, 4483533, 4490295, 4500579, 4519552, 4521741, 4533313, 4548534, 4588762, 4611617, 4636868, 4649209, 4671414, 4676703, 4677065, 4681445, 4683766, 4695973, 4725478, 4741846, 4743826, 4746821, 4766523, 4773755, 4774000, 4780167, 4792897, 4825817, 4827175, 4847358, 4848217, 4858943, 4859868, 4864690, 4867683, 4872413, 4884978, 4895066, 4929425, 4930502, 4947845, 4960851, 4969176, 4987353, 5012047, 5014168, 5029598, 5030992, 5038419, 5045189, 5047017, 5048285, 5057869, 5058259, 5102907, 5109122, 5117217, 5133431, 5139803, 5146615, 5165685, 5171753, 5172395, 5173291, 5179784, 5191955, 5195956, 5209311, 5215887, 5231738, 5265131, 5290020, 5304413, 5321526, 5328792, 5335779, 5342499, 5354190, 5354837, 5357902, 5359007, 5365736, 5380122, 5387698, 5404678, 5404721, 5405535, 5405921, 5435667, 5438658, 5451338, 5470518, 5479486, 5489881, 5524001, 5533026, 5535906, 5547058, 5577158, 5583370, 5598113, 5601419, 5601765, A_51_P391655, A_52_P440709, x83933_s_at
    Baseline Expression Baseline expression in tissue(s) was found for ENSMUSG00000021313
c Expression Level cut-off: 0.5
    Differential Expression 5 search result(s) found
5 search result(s) found cutoffs: adjusted p-value 0.05    log2-fold change 1.0