Expression Atlas results for ENSMUSG00000007613

    Tgfbr1 Mus musculus transforming growth factor, beta receptor I
Synonyms ALK5, Alk-5, TbetaR-I, TbetaRI
Orthologs TGFBR1 (Bos taurus), TGFBR1 (Canis familiaris), ENSCING00000014075 (Ciona intestinalis), ENSCSAVG00000001900 (Ciona savignyi), tgfbr1a (Danio rerio), tgfbr1b (Danio rerio), ALK5 (Equus caballus), TGFBR1 (Homo sapiens), CHALK5 (Gallus gallus), TGFBR1 (Macaca mulatta), Tgfbr1 (Rattus norvegicus), Tgfbr1 (Rattus norvegicus), TGFBR1 (Sus scrofa), ENSSSCG00000023995 (Sus scrofa), tgfbr1 (Xenopus tropicalis), babo (Drosophila melanogaster)
Gene Ontology activation of MAPKK activity, skeletal system development, angiogenesis, in utero embryonic development, kidney development, blastocyst development, epithelial to mesenchymal transition, negative regulation of endothelial cell proliferation, lens development in camera-type eye, protein kinase activity, protein serine/threonine kinase activity, transmembrane receptor protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, protein tyrosine kinase activity, transforming growth factor beta-activated receptor activity, transforming growth factor beta receptor activity, type I, type II transforming growth factor beta receptor binding, protein binding, ATP binding, endosome, plasma membrane, caveola, tight junction, regulation of transcription, DNA-templated, protein phosphorylation, apoptotic process, signal transduction, transforming growth factor beta receptor signaling pathway, heart development, positive regulation of cell proliferation, germ cell migration, post-embryonic development, anterior/posterior pattern specification, regulation of gene expression, positive regulation of pathway-restricted SMAD protein phosphorylation, membrane, integral component of membrane, transferase activity, transferring phosphorus-containing groups, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, growth factor binding, signal transduction by phosphorylation, collagen fibril organization, positive regulation of cell growth, regulation of protein ubiquitination, negative regulation of chondrocyte differentiation, negative regulation of apoptotic process, receptor complex, regulation of protein binding, endothelial cell migration, membrane raft, positive regulation of transcription, DNA-templated, SMAD binding, metal ion binding, thymus development, neuron fate commitment, embryonic cranial skeleton morphogenesis, skeletal system morphogenesis, artery morphogenesis, cell motility, transforming growth factor beta binding, positive regulation of cellular component movement, positive regulation of filopodium assembly, positive regulation of protein kinase B signaling, parathyroid gland development, palate development, pharyngeal system development, pathway-restricted SMAD protein phosphorylation, positive regulation of SMAD protein import into nucleus, I-SMAD binding, response to cholesterol, cellular response to transforming growth factor beta stimulus, positive regulation of apoptotic signaling pathway, negative regulation of extrinsic apoptotic signaling pathway
InterPro TGF-beta receptor/activin receptor, type I/II (domain), Protein kinase domain (domain), Serine-threonine/tyrosine-protein kinase catalytic domain (domain), Serine/threonine- /dual specificity protein kinase, catalytic domain (domain), TGF beta receptor, GS motif (domain), Protein kinase-like domain (domain), Tyrosine-protein kinase, catalytic domain (domain)
Ensembl Family TGF BETA RECEPTOR TYPE 1 PRECURSOR TGFR 1 EC_2.7.11.30 TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE I TGF BETA RECEPTOR TYPE I TBETAR I
Ensembl Gene ENSMUSG00000007613
Entrez 21812
UniProt E9Q418, Q3U485, Q4FJL1, Q64729, Q9CVP4, Q9D5H8
EMAGE MGI:98728
MGI transforming growth factor, beta receptor I
Gene Biotype protein_coding
Design Element 10504817, 106644_at, 1420893_a_at, 1420894_at, 1420895_at, 4355548, 4431045, 4455593, 4480905, 4519309, 4710787, 4890052, 4905530, 4908316, 5034160, 5227658, 5367563, 5458612, 5476760, 5579347, 5603436, 92427_at, A_51_P280137, A_52_P4538, A_55_P1960901, A_55_P1960906, A_55_P2137206, A_55_P2137211, d25540_s_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 24 results
Showing 24 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0