Expression Atlas results for ENSMUSG00000002603

    Tgfb1 Mus musculus transforming growth factor, beta 1
Synonyms TGF-beta 1, TGF-beta1, TGFbeta1, Tgfb, Tgfb-1
Orthologs TGFB1 (Bos taurus), tgfbeta2 (Ciona intestinalis), ENSCSAVG00000002907 (Ciona savignyi), tgfb1b (Danio rerio), tgfb1a (Danio rerio), TGFB1 (Equus caballus), TGFB1 (Homo sapiens), TGFB1 (Macaca mulatta), Tgfb1 (Rattus norvegicus), TGFB1 (Sus scrofa), ENSSSCG00000026296 (Sus scrofa), tgfb1 (Xenopus tropicalis), daw (Drosophila melanogaster)
Gene Ontology protein import into nucleus, translocation, negative regulation of transcription from RNA polymerase II promoter, MAPK cascade, skeletal system development, ureteric bud development, response to hypoxia, morphogenesis of a branching structure, cell activation, epithelial to mesenchymal transition, negative regulation of protein phosphorylation, positive regulation of protein phosphorylation, glycoprotein binding, regulation of sodium ion transport, chondrocyte differentiation, hematopoietic progenitor cell differentiation, adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, tolerance induction to self antigen, antigen binding, type II transforming growth factor beta receptor binding, transforming growth factor beta receptor binding, protein binding, proteinaceous extracellular matrix, extracellular space, nucleus, cytoplasm, microvillus, protein phosphorylation, protein export from nucleus, ATP biosynthetic process, phosphate-containing compound metabolic process, cellular calcium ion homeostasis, defense response, inflammatory response, cell cycle arrest, mitotic cell cycle checkpoint, epidermal growth factor receptor signaling pathway, transforming growth factor beta receptor signaling pathway, common-partner SMAD protein phosphorylation, SMAD protein complex assembly, SMAD protein import into nucleus, negative regulation of neuroblast proliferation, salivary gland morphogenesis, endoderm development, skeletal muscle tissue development, female pregnancy, aging, growth factor activity, negative regulation of DNA replication, cell proliferation, positive regulation of cell proliferation, negative regulation of cell proliferation, germ cell migration, response to radiation, response to wounding, response to glucose, embryo development, defense response to fungus, incompatible interaction, organ morphogenesis, cell surface, response to organic substance, positive regulation of gene expression, negative regulation of gene expression, positive regulation of epithelial to mesenchymal transition, positive regulation of fibroblast migration, positive regulation of peptidyl-threonine phosphorylation, positive regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of macrophage cytokine production, response to organic cyclic compound, cell growth, regulation of striated muscle tissue development, regulation of transforming growth factor beta receptor signaling pathway, evasion or tolerance of host defenses by virus, enzyme binding, negative regulation of cell-cell adhesion, secretory granule, hyaluronan catabolic process, T cell differentiation, negative regulation of ossification, negative regulation of cell growth, positive regulation of cell migration, axon, positive regulation of bone mineralization, mammary gland development, extracellular matrix, positive regulation of histone deacetylation, organ regeneration, positive regulation of protein complex assembly, positive regulation of exit from mitosis, lipopolysaccharide-mediated signaling pathway, positive regulation of cellular protein metabolic process, response to estradiol, response to progesterone, positive regulation of interleukin-17 production, receptor catabolic process, positive regulation of superoxide anion generation, mononuclear cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of peptidyl-serine phosphorylation, response to vitamin D, response to laminar fluid shear stress, positive regulation of histone acetylation, positive regulation of protein dephosphorylation, growth, wound healing, T cell activation, regulation of cell proliferation, negative regulation of T cell proliferation, regulation of protein import into nucleus, positive regulation of protein import into nucleus, positive regulation of odontogenesis, response to drug, myelination, protein homodimerization activity, myeloid dendritic cell differentiation, neuronal cell body, T cell homeostasis, positive regulation of apoptotic process, positive regulation of MAP kinase activity, protein kinase B signaling, positive regulation of blood vessel endothelial cell migration, negative regulation of blood vessel endothelial cell migration, positive regulation of phosphatidylinositol 3-kinase activity, ossification involved in bone remodeling, regulatory T cell differentiation, cell-cell junction organization, negative regulation of fat cell differentiation, negative regulation of myoblast differentiation, negative regulation of cell cycle, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, negative regulation of mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, protein heterodimerization activity, protein N-terminus binding, positive regulation of isotype switching to IgA isotypes, lymph node development, digestive tract development, negative regulation of skeletal muscle tissue development, inner ear development, positive regulation of epithelial cell proliferation, negative regulation of epithelial cell proliferation, positive regulation of protein secretion, negative regulation of phagocytosis, negative regulation of immune response, negative regulation of T cell activation, positive regulation of chemotaxis, positive regulation of NF-kappaB transcription factor activity, regulation of binding, regulation of DNA binding, positive regulation of smooth muscle cell differentiation, negative regulation of release of sequestered calcium ion into cytosol, positive regulation of cell division, positive regulation of protein kinase B signaling, face morphogenesis, frontal suture morphogenesis, pathway-restricted SMAD protein phosphorylation, positive regulation of SMAD protein import into nucleus, mammary gland branching involved in thelarche, branch elongation involved in mammary gland duct branching, regulation of branching involved in mammary gland duct morphogenesis, regulation of cartilage development, lens fiber cell differentiation, response to cholesterol, positive regulation of cell cycle arrest, cellular response to growth factor stimulus, cellular response to organic cyclic compound, cellular response to dexamethasone stimulus, cellular response to transforming growth factor beta stimulus, blood microparticle, extracellular matrix assembly, positive regulation of branching involved in ureteric bud morphogenesis, extrinsic apoptotic signaling pathway, negative regulation of hyaluronan biosynthetic process, positive regulation of protein localization to nucleus, positive regulation of NAD+ ADP-ribosyltransferase activity, regulation of actin cytoskeleton reorganization, regulation of miRNA metabolic process, positive regulation of transcription regulatory region DNA binding
InterPro Transforming growth factor-beta, N-terminal (domain), Transforming growth factor-beta, C-terminal (domain), Transforming growth factor, beta 1 (family), Transforming growth factor-beta (family), Cystine-knot cytokine (domain)
Ensembl Family TRANSFORMING GROWTH FACTOR BETA PRECURSOR TGF BETA [CONTAINS LATENCY ASSOCIATED PEPTIDE LAP ], UNKNOWN
Ensembl Gene ENSMUSG00000002603
Entrez 21803
UniProt E9Q6I6, P04202, Q3UNK5
EMAGE MGI:98725
MGI transforming growth factor, beta 1
Gene Biotype protein_coding
Design Element 101918_at, 10551185, 1420653_at, 1427947_at, 4527291, 4562682, 4565053, 4583218, 4700619, 4768711, 4811074, 4994299, 5044933, 5071421, 5095147, 5218028, 5268901, 5428214, 5579249, A_51_P390715, A_51_P487228, Msa.1226.0_g_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 27 results
Showing 27 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0