AKR1C4

aldo-keto reductase family 1, member C4

Synonyms 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581
Orthologs ENSBTAG00000017938 (Bos taurus), ENSBTAG00000021368 (Bos taurus), ENSBTAG00000022564 (Bos taurus), ENSBTAG00000022570 (Bos taurus), ENSBTAG00000022571 (Bos taurus), ENSBTAG00000027419 (Bos taurus), ENSBTAG00000037453 (Bos taurus), ENSBTAG00000037509 (Bos taurus), ENSBTAG00000039289 (Bos taurus), ENSBTAG00000039356 (Bos taurus), ENSBTAG00000039643 (Bos taurus), ENSBTAG00000039722 (Bos taurus), ENSBTAG00000040393 (Bos taurus), ENSCHOG00000003414, ENSCHOG00000008668, ENSCHOG00000009179, ENSCHOG00000009548, ENSCHOG00000009853, ENSCHOG00000011522, ENSCHOG00000013698, ENSCING00000007642 (Ciona intestinalis), ENSCJAG00000020469, ENSCPOG00000000371, ENSCPOG00000003089, ENSCPOG00000025134, AKR1C4 (Chlorocebus sabaeus), ENSDNOG00000007344 (Dasypus novemcinctus), ENSDNOG00000010153 (Dasypus novemcinctus), ENSDNOG00000015013 (Dasypus novemcinctus), ENSDNOG00000034002 (Dasypus novemcinctus), ENSDNOG00000042971 (Dasypus novemcinctus), ENSDNOG00000046447 (Dasypus novemcinctus), ENSDORG00000002849, ENSDORG00000002850, ENSDORG00000002907, ENSDORG00000003009, ENSDORG00000003234, ENSDORG00000003858, ENSDORG00000005105, ENSDORG00000006536, ENSDORG00000009940, ENSECAG00000008302 (Equus caballus), ENSECAG00000008312 (Equus caballus), ENSECAG00000008599 (Equus caballus), ENSECAG00000011784 (Equus caballus), ENSECAG00000012350 (Equus caballus), ENSECAG00000014685 (Equus caballus), ENSECAG00000018315 (Equus caballus), ENSECAG00000019480 (Equus caballus), AKR1C1 (Equus caballus), ENSETEG00000005664, ENSETEG00000009155, AKR1C4 (Gorilla gorilla), ENSLAFG00000009654, ENSLAFG00000012027, ENSLAFG00000025833, ENSLAFG00000027242, ENSLAFG00000028887, ENSLAFG00000030500, ENSMEUG00000005767, ENSMEUG00000015743, ENSMEUG00000016689, ENSMICG00000007861, ENSMICG00000016217, AKR1C4 (Macaca mulatta), ENSMODG00000018492 (Monodelphis domestica), Akr1c21 (Mus musculus), Akr1c6 (Mus musculus), Akr1c12 (Mus musculus), Akr1c13 (Mus musculus), Akr1c18 (Mus musculus), Akr1cl (Mus musculus), Akr1c14 (Mus musculus), Akr1c20 (Mus musculus), Akr1c19 (Mus musculus), ENSNLEG00000011321, ENSOANG00000015467, ENSOANG00000015470, ENSOANG00000019734, ENSOANG00000028916, ENSOARG00000009277 (Ovis aries), ENSOARG00000009642 (Ovis aries), ENSOARG00000009762 (Ovis aries), ENSOARG00000010028 (Ovis aries), ENSOARG00000010221 (Ovis aries), ENSOARG00000010355 (Ovis aries), ENSOARG00000010449 (Ovis aries), ENSOARG00000010488 (Ovis aries), ENSOARG00000010577 (Ovis aries), ENSOARG00000010661 (Ovis aries), ENSOARG00000010907 (Ovis aries), ENSOARG00000011087 (Ovis aries), ENSOARG00000011490 (Ovis aries), ENSOARG00000011663 (Ovis aries), ENSOARG00000011857 (Ovis aries), ENSOARG00000012196 (Ovis aries), ENSOARG00000012476 (Ovis aries), ENSOCUG00000004733, ENSOCUG00000005825, ENSOCUG00000009175, ENSOCUG00000012095, ENSOCUG00000012841 (Oryctolagus cuniculus), ENSOCUG00000014318 (Oryctolagus cuniculus), ENSOCUG00000014326, ENSOCUG00000017797, ENSOCUG00000021938 (Oryctolagus cuniculus), ENSOCUG00000022121 (Oryctolagus cuniculus), ENSOCUG00000022139, ENSOCUG00000026267, ENSOCUG00000026577, ENSOCUG00000026898, ENSOCUG00000027165 (Oryctolagus cuniculus), ENSOGAG00000026428, ENSOGAG00000033885, ENSOPRG00000003111, ENSOPRG00000013801, ENSOPRG00000014225, AKR1C4 (Papio anubis), ENSPCAG00000000562, ENSPCAG00000007331, ENSPCAG00000007571, ENSPCAG00000015452, ENSPCAG00000016853, AKR1C4 (Pongo abelii), ENSPSIG00000015159, ENSPSIG00000015380, ENSPSIG00000016453, AKR1C4 (Pan troglodytes), Akr1c3 (Rattus norvegicus), Akr1c14 (Rattus norvegicus), Akr1c2 (Rattus norvegicus), Akr1c12 (Rattus norvegicus), Akr1c19 (Rattus norvegicus), Akr1c1 (Rattus norvegicus), RGD1564865 (Rattus norvegicus), Akr1c13 (Rattus norvegicus), Akr1c12l1 (Rattus norvegicus), ENSSHAG00000006005, ENSSSCG00000011147 (Sus scrofa), ENSSSCG00000011148 (Sus scrofa), ENSSSCG00000011153 (Sus scrofa), ENSSTOG00000011910, ENSSTOG00000020872, ENSSTOG00000022442, ENSVPAG00000003362, ENSVPAG00000004504, ENSVPAG00000010473, akr1c8p (Xenopus tropicalis), ENSXETG00000016564 (Xenopus tropicalis), akr1c8p (Xenopus tropicalis), akr1c2 (Xenopus tropicalis), ENSXETG00000023822 (Xenopus tropicalis), akr1c1 (Xenopus tropicalis), CG10863 (Drosophila melanogaster), CG9436 (Drosophila melanogaster), CG12766 (Drosophila melanogaster), CG6083 (Drosophila melanogaster), CG10638 (Drosophila melanogaster), FBgn0058064, CG6084 (Drosophila melanogaster), C07D8.5 (Caenorhabditis elegans), YPR1 (Saccharomyces cerevisiae), GCY1 (Saccharomyces cerevisiae)
Gene Ontology
InterPro Aldo/keto reductase, conserved site (conserved_site), Aldo/keto reductase subgroup (family), NADP-dependent oxidoreductase domain (domain)
Ensembl Family ALDO KETO REDUCTASE FAMILY 1 MEMBER C4 EC_1.1.1.- 3 ALPHA HSD1 3 ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE I EC_1.1.1.357 CHLORDECONE REDUCTASE CDR EC_1.1.-.- 1 225 DIHYDRODIOL DEHYDROGENASE 4 DD 4 DD4
Ensembl Gene ENSG00000198610
Entrez 1109
UniProt P17516
Gene Biotype protein_coding
Design Element 16702026, 210558_at, 3233005, 3233012, 3233013, 3233063, 3233074, 3233120, 3233121, 3233122, 3233123, 3233124, 3233125, 3233126, 3233127, 3233128, 3233129, 3233130, 3233132, 3233133, 3233134, 3233136, 3233137, 3233138, 3274771, 3274773, 3274778, 3274835, 35482_at, 7925939, A_33_P3272291, S68287_at, g9186907_3p_at