Expression Atlas results for ENSG00000188906

    LRRK2 Homo sapiens leucine-rich repeat kinase 2
Synonyms DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
Orthologs LRRK2 (Bos taurus), LRRK2 (Canis familiaris), ENSCSAVG00000006539 (Ciona savignyi), lrrk2 (Danio rerio), LRRK2 (Equus caballus), LRRK2 (Gallus gallus), LRRK2 (Macaca mulatta), ENSMMUG00000032029 (Macaca mulatta), Lrrk2 (Mus musculus), Lrrk2 (Rattus norvegicus), LRRK2 (Sus scrofa), lrrk2 (Xenopus tropicalis), Lrrk (Drosophila melanogaster), lrk-1 (Caenorhabditis elegans)
Gene Ontology ATP binding, GTP binding, GTP catabolic process, GTP-dependent protein kinase activity, GTPase activator activity, GTPase activity, MAP kinase kinase activity, MAPK cascade, Rho GTPase binding, activation of MAPK activity, activation of MAPKK activity, autophagy, axon, binding, cellular response to organic cyclic compound, cytoplasm, dendrite, dendrite cytoplasm, determination of adult lifespan, exploration behavior, external side of mitochondrial outer membrane, identical protein binding, intracellular, intracellular distribution of mitochondria, intracellular membrane-bounded organelle, ion channel binding, membrane, membrane raft, mitochondrion, negative regulation of GTPase activity, negative regulation of branching morphogenesis of a nerve, negative regulation of dendritic spine morphogenesis, negative regulation of neuroblast proliferation, negative regulation of neuron maturation, neuromuscular junction development, neuron death, neuron projection, neuronal cell body, olfactory bulb development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, plasma membrane, positive regulation of GTPase activity, positive regulation of autophagy, positive regulation of cell death, positive regulation of dopamine receptor signaling pathway, positive regulation of programmed cell death, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination, protein autophosphorylation, protein binding, protein homodimerization activity, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activity, protein transport, protein tyrosine kinase activity, regulation of kidney size, regulation of locomotion, regulation of membrane potential, response to oxidative stress, small GTPase mediated signal transduction, synapse, synaptic vesicle, tangential migration from the subventricular zone to the olfactory bulb, trans-Golgi network, transferase activity, transferring phosphorus-containing groups, tubulin binding
InterPro Ankyrin repeat-containing domain, Armadillo-type fold, Leucine-rich repeat, Leucine-rich repeat, typical subtype, Mitochondrial Rho-like, P-loop containing nucleoside triphosphate hydrolase, Protein kinase domain, Protein kinase-like domain, Serine-threonine/tyrosine-protein kinase catalytic domain, Serine/threonine- / dual specificity protein kinase, catalytic domain, Small GTP-binding protein domain, Small GTPase superfamily, Small GTPase superfamily, ARF/SAR type, Small GTPase superfamily, Rab type, Tyrosine-protein kinase, catalytic domain, WD40-repeat-containing domain
Ensembl Gene ENSG00000188906
Entrez 120892
UniProt A2VED2, C9JBF0, E9PC85, Q5S007
Gene Biotype protein_coding
Design Element 229584_at, 3411325, 3411329, 3411330, 3411332, 3411333, 3411335, 3411336, 3411337, 3411341, 3411343, 3411344, 3411345, 3411346, 3411347, 3411348, 3411349, 3411350, 3411351, 3411354, 3411355, 3411356, 3411357, 3411358, 3411359, 3411360, 3411361, 3411362, 3411363, 3411364, 3411365, 3411366, 3411367, 3411368, 3411369, 3411370, 3411371, 3411372, 3411373, 3411374, 3411376, 3411377, 3411379, 3411380, 3411381, 3411383, 3411385, 3411386, 3411389, 3411391, 3411392, 3411394, 3411396, 3411397, 3411398, 3411399, 3411402, 3411404, 3411405, 3411407, 3411408, 3411409, 3411410, 3411411, 3411412, 3411413, 3411414, 3411415, 51362_at, 7954810, 81790_at, A_23_P128447, A_33_P3369058, A_33_P3389872, Hs.124292.0.A1_3p_at
    Baseline Expression Baseline expression in tissue(s) was found for ENSG00000188906
c Expression Level cut-off: 0.5
    Differential Expression 12 search result(s) found
12 search result(s) found cutoffs: adjusted p-value 0.05    log2-fold change 1.0