Expression Atlas results for ENSG00000185345

    PARK2 Homo sapiens parkin RBR E3 ubiquitin protein ligase
Synonyms AR-JP, PDJ, parkin
Orthologs PARK2 (Bos taurus), ENSCAFG00000000769 (Canis familiaris), ENSCAFG00000032456 (Canis familiaris), park2 (Danio rerio), PARK2 (Equus caballus), PARK2 (Gallus gallus), PARK2 (Macaca mulatta), Park2 (Mus musculus), Park2 (Rattus norvegicus), PARK2 (Sus scrofa), ENSSSCG00000026205 (Sus scrofa), park (Drosophila melanogaster), pdr-1 (Caenorhabditis elegans)
Gene Ontology ubiquitin ligase complex, protein polyubiquitination, mitochondrion degradation, negative regulation of protein phosphorylation, synaptic transmission, dopaminergic, startle response, ubiquitin-protein transferase activity, protein binding, nucleus, cytoplasm, mitochondrion, endoplasmic reticulum, Golgi apparatus, cytosol, transcription, DNA-templated, regulation of transcription, DNA-templated, ubiquitin-dependent protein catabolic process, protein monoubiquitination, central nervous system development, learning, locomotory behavior, cell death, zinc ion binding, adult locomotory behavior, regulation of autophagy, aggresome, protein ubiquitination, ligase activity, protein metabolic process, kinase binding, protein kinase binding, PDZ domain binding, ubiquitin protein ligase binding, negative regulation of actin filament bundle assembly, negative regulation of glucokinase activity, synaptic transmission, glutamatergic, norepinephrine metabolic process, dopamine metabolic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, identical protein binding, neuron projection, positive regulation of I-kappaB kinase/NF-kappaB signaling, proteasome-mediated ubiquitin-dependent protein catabolic process, protein complex, negative regulation of neuron apoptotic process, cellular protein catabolic process, negative regulation of insulin secretion, regulation of neurotransmitter secretion, perinuclear region of cytoplasm, regulation of synaptic transmission, chaperone binding, dopamine uptake involved in synaptic transmission, protein autoubiquitination, negative regulation of cell death, protein K63-linked ubiquitination, aggresome assembly, protein K48-linked ubiquitination, neuron death, negative regulation of release of cytochrome c from mitochondria, regulation of reactive oxygen species metabolic process
InterPro Ubiquitin-like (domain), Zinc finger, C6HC-type (domain), E3 ubiquitin-protein ligase parkin (family), Ubiquitin (family), Rad60/SUMO-like domain (domain), Ubiquitin-related domain (domain)
Ensembl Family E3 UBIQUITIN LIGASE PARKIN EC_6.3.2.-, UNKNOWN
Ensembl Gene ENSG00000185345
Entrez 5071
UniProt B1AKC3, M4T2U2, O60260, Q5XNR7, Q6Q2I8, Q6S8G7, S4X465, X5DR79
Gene Biotype protein_coding
Design Element 1554855_at, 1555668_a_at, 207058_s_at, 2983144, 2983145, 2983146, 2983147, 2983148, 2983149, 2983152, 2983160, 2983207, 2983209, 2983217, 2983258, 2983288, 2983308, 2983309, 2983321, 2983326, 2983327, 2983328, 2983351, 2983399, 33019_at, 8130645, 86935_r_at, A_23_P136077, A_23_P147465, Hs2.132954.4.S1_3p_at, Hs2.132954.6.S1_3p_s_at, g4758883_3p_a_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 2 results
Showing 2 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0