Expression Atlas results for ENSG00000145335

    SNCA Homo sapiens synuclein, alpha (non A4 component of amyloid precursor)
Synonyms NACP, PARK1, PARK4, PD1, alpha-synuclein
Orthologs SNCA (Bos taurus), SNCA (Canis familiaris), sncga (Danio rerio), SNCA (Equus caballus), SNCA (Gallus gallus), SNCA (Macaca mulatta), Snca (Mus musculus), Snca (Rattus norvegicus), SNCA (Sus scrofa), snca (Xenopus tropicalis)
Gene Ontology Golgi apparatus, Hsp70 protein binding, actin cytoskeleton, activation of cysteine-type endopeptidase activity involved in apoptotic process, adult locomotory behavior, aging, alpha-tubulin binding, arachidonic acid binding, axon, axon terminus, behavioral response to cocaine, beta-tubulin binding, calcium ion binding, cell cortex, cell junction, cellular response to copper ion, cellular response to epinephrine stimulus, cellular response to fibroblast growth factor stimulus, cellular response to oxidative stress, copper ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytoplasm, cytoplasmic vesicle membrane, cytoskeleton, cytosol, dopamine biosynthetic process, dopamine metabolic process, dopamine uptake involved in synaptic transmission, dynein binding, enzyme binding, extracellular fibril organization, extracellular region, fatty acid metabolic process, ferrous iron binding, fibril, growth cone, histone binding, identical protein binding, inclusion body, intracellular membrane-bounded organelle, kinesin binding, long-term synaptic potentiation, magnesium ion binding, microglial cell activation, microtubule binding, mitochondrial ATP synthesis coupled electron transport, mitochondrial membrane organization, mitochondrion, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dopamine metabolic process, negative regulation of dopamine uptake involved in synaptic transmission, negative regulation of exocytosis, negative regulation of histone acetylation, negative regulation of microtubule polymerization, negative regulation of monooxygenase activity, negative regulation of neuron apoptotic process, negative regulation of norepinephrine uptake, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of protein phosphorylation, negative regulation of serotonin uptake, negative regulation of thrombin receptor signaling pathway, negative regulation of transporter activity, neutral lipid metabolic process, nuclear outer membrane, nucleus, oxidation-reduction process, oxidoreductase activity, perinuclear region of cytoplasm, phospholipase binding, phospholipid binding, phospholipid metabolic process, phosphoprotein binding, plasma membrane, platelet alpha granule membrane, positive regulation of endocytosis, positive regulation of inositol phosphate biosynthetic process, positive regulation of neurotransmitter secretion, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein serine/threonine kinase activity, positive regulation of receptor recycling, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of synaptic transmission, protein N-terminus binding, protein binding, protein destabilization, protein domain specific binding, receptor internalization, regulation of acyl-CoA biosynthetic process, regulation of dopamine secretion, regulation of excitatory postsynaptic membrane potential, regulation of glutamate secretion, regulation of locomotion, regulation of long-term neuronal synaptic plasticity, regulation of macrophage activation, regulation of neuronal synaptic plasticity, regulation of neurotransmitter secretion, regulation of phospholipase activity, response to cocaine, response to drug, response to interferon-gamma, response to interleukin-1, response to iron(II) ion, response to lipopolysaccharide, response to magnesium ion, ribosome, rough endoplasmic reticulum, synapse, synapse organization, synaptic transmission, synaptic transmission, dopaminergic, synaptic vesicle, synaptic vesicle endocytosis, synaptic vesicle transport, tau protein binding, terminal bouton, zinc ion binding
InterPro Alpha-synuclein, Gamma-synuclein, Synuclein
Ensembl Family ALPHA SYNUCLEIN
Ensembl Gene ENSG00000145335
Entrez 6622
UniProt D6RA31, E7EPV7, F6L6N6, H6UYS0, H6UYS5, P37840, Q4W5L2
Gene Biotype protein_coding
Design Element 204466_s_at, 204467_s_at, 207827_x_at, 211546_x_at, 236081_at, 2777711, 2777712, 2777715, 2777716, 2777717, 2777718, 2777719, 2777722, 2777742, 2777743, 2777744, 2777746, 2777749, 2777750, 2777751, 2777752, 2777753, 2777754, 2777756, 3468050, 37291_r_at, 44191_at, 8101762, A_23_P29939, A_32_P109653, Hs.21374.0.A1_3p_at, Hs.76930.1.A1_3p_a_at, U46901_at, g556211_3p_x_at, g556213_3p_a_at, g6806896_3p_a_at
    Baseline Expression Baseline expression in tissue(s) was found for ENSG00000145335
c Expression Level cut-off: 0.5
    Differential Expression 15 search result(s) found
15 search result(s) found cutoffs: adjusted p-value 0.05    log2-fold change 1.0