Expression Atlas results for ENSG00000142192

    APP Homo sapiens amyloid beta (A4) precursor protein
Synonyms AD1
Orthologs APP (Bos taurus), APP (Canis familiaris), ENSDARG00000026738 (Danio rerio), appb (Danio rerio), appa (Danio rerio), APP (Equus caballus), APP (Gallus gallus), APP (Macaca mulatta), App (Mus musculus), App (Rattus norvegicus), APP (Sus scrofa), app (Xenopus tropicalis), Appl (Drosophila melanogaster), apl-1 (Caenorhabditis elegans)
Gene Ontology mitotic G2 phase, suckling behavior, platelet degranulation, DNA binding, serine-type endopeptidase inhibitor activity, receptor binding, protein binding, extracellular region, extracellular space, nuclear envelope lumen, cytoplasm, Golgi apparatus, cytosol, plasma membrane, integral component of plasma membrane, coated pit, cell-cell junction, mRNA polyadenylation, regulation of translation, protein phosphorylation, cellular copper ion homeostasis, endocytosis, response to oxidative stress, cell adhesion, regulation of epidermal growth factor-activated receptor activity, Notch signaling pathway, nervous system development, axonogenesis, blood coagulation, mating behavior, locomotory behavior, axon cargo transport, heparin binding, cholesterol metabolic process, adult locomotory behavior, visual learning, cell surface, regulation of gene expression, negative regulation of endopeptidase activity, positive regulation of peptidase activity, positive regulation of G2/M transition of mitotic cell cycle, membrane, integral component of membrane, axon midline choice point recognition, neuron remodeling, dendrite development, peptidase activator activity, enzyme binding, ER to Golgi transport vesicle, platelet activation, extracellular matrix organization, axon, forebrain development, platelet alpha granule lumen, neuron projection development, cytoplasmic vesicle, neuromuscular junction, acetylcholine receptor binding, ionotropic glutamate receptor signaling pathway, ciliary rootlet, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, regulation of multicellular organism growth, identical protein binding, neuron projection, dendritic spine, dendritic shaft, intracellular membrane-bounded organelle, receptor complex, regulation of protein binding, innate immune response, membrane raft, apical part of cell, synapse, negative regulation of neuron differentiation, positive regulation of mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, transition metal ion binding, perinuclear region of cytoplasm, collateral sprouting in absence of injury, regulation of synapse structure and activity, neuromuscular process controlling balance, synaptic growth at neuromuscular junction, spindle midzone, neuron apoptotic process, PTB domain binding, smooth endoplasmic reticulum calcium ion homeostasis, extracellular vesicular exosome, growth factor receptor binding
InterPro Proteinase inhibitor I2, Kunitz metazoa (domain), Amyloidogenic glycoprotein, extracellular (domain), Amyloidogenic glycoprotein (family), Amyloidogenic glycoprotein, copper-binding (domain), Amyloidogenic glycoprotein, amyloid-beta peptide (domain), Amyloidogenic glycoprotein, heparin-binding (domain), Beta-amyloid precursor protein C-terminal (domain), Amyloidogenic glycoprotein, E2 domain (domain)
Ensembl Family AMYLOID BETA A4 PRECURSOR ABPP APP ALZHEIMER DISEASE AMYLOID A4 HOMOLOG [CONTAINS N APP; SOLUBLE APP ALPHA S APP ALPHA ; SOLUBLE APP BETA S APP BETA ; BETA AMYLOID 42 BETA APP42 ; BETA AMYLOID 40 BETA APP40 ; C83; P3 42 ; P3 40 ; C80; GAMMA SECRETASE C TE
Ensembl Gene ENSG00000142192
Entrez 351
UniProt B7Z313, E9PEV0, E9PG40, H7C104, L7XCZ9, L7XE61, P05067
Gene Biotype protein_coding
Design Element 200602_at, 211277_3p_x_at, 211277_x_at, 214953_s_at, 3927225, 3927227, 3927228, 3927229, 3927230, 3927233, 3927234, 3927235, 3927237, 3927241, 3927242, 3927255, 3927262, 3927264, 3927269, 3927270, 3927271, 3927272, 3927273, 3927274, 3927280, 3927281, 3927282, 3927285, 3927286, 3927289, 3927298, 3927300, 3927301, 3927305, 3927306, 3927307, 3927320, 3927334, 3927335, 3927336, 3927337, 3927338, 41136_s_at, 64309_f_at, 70660_at, 8069644, A_24_P314159, A_33_P3296479, A_33_P3508822, Hs.177486.2.A1_3p_a_at, Y00264_at, g13325111_3p_at, g13325111_3p_x_at, g4502166_3p_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 14 results
Showing 14 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0