Expression Atlas results for ENSG00000141646

    SMAD4 Homo sapiens SMAD family member 4
Synonyms DPC4, MADH4
Orthologs SMAD4 (Bos taurus), MADH4 (Canis familiaris), CI-SMAD4 (Ciona intestinalis), ENSCSAVG00000006480 (Ciona savignyi), smad4 (Danio rerio), SMAD4 (2 of 2) (Danio rerio), SMAD4 (Equus caballus), SMAD4 (Macaca mulatta), Smad4 (Mus musculus), Smad4 (Rattus norvegicus), SMAD4 (Sus scrofa), smad4.1 (Xenopus tropicalis), Med (Drosophila melanogaster), sma-4 (Caenorhabditis elegans)
Gene Ontology negative regulation of transcription from RNA polymerase II promoter, nuclear chromatin, core promoter proximal region sequence-specific DNA binding, protein binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding, branching involved in ureteric bud morphogenesis, response to hypoxia, in utero embryonic development, gastrulation with mouth forming second, kidney development, atrioventricular valve formation, epithelial to mesenchymal transition involved in endocardial cushion formation, positive regulation of cell proliferation involved in heart valve morphogenesis, cardiac septum development, brainstem development, DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, protein binding, collagen binding, intracellular, nucleus, nucleoplasm, transcription factor complex, cytoplasm, centrosome, cytosol, transcription, DNA-templated, regulation of transcription, DNA-templated, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transforming growth factor beta receptor signaling pathway, SMAD protein complex assembly, gastrulation, axon guidance, endoderm development, mesoderm development, cell proliferation, negative regulation of cell proliferation, anterior/posterior pattern specification, gene expression, positive regulation of epithelial to mesenchymal transition, positive regulation of pathway-restricted SMAD protein phosphorylation, neural crest cell differentiation, regulation of transforming growth factor beta receptor signaling pathway, negative regulation of cell growth, BMP signaling pathway, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of BMP signaling pathway, transforming growth factor beta receptor, common-partner cytoplasmic mediator activity, activin responsive factor complex, somite rostral/caudal axis specification, regulation of transforming growth factor beta2 production, intracellular signal transduction, atrioventricular canal development, endothelial cell activation, regulation of cell proliferation, negative regulation of protein catabolic process, identical protein binding, protein homodimerization activity, sequence-specific DNA binding, transcription regulatory region DNA binding, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, metal ion binding, developmental growth, neuron fate commitment, tissue morphogenesis, sebaceous gland development, formation of anatomical boundary, regulation of binding, regulation of hair follicle development, palate development, positive regulation of SMAD protein import into nucleus, SMAD protein signal transduction, negative regulation of cell death, endocardial cell differentiation, I-SMAD binding, R-SMAD binding, SMAD protein complex, response to transforming growth factor beta, metanephric mesenchyme morphogenesis, nephrogenic mesenchyme morphogenesis
InterPro SMAD domain, Dwarfin-type (domain), MAD homology 1, Dwarfin-type (domain), SMAD/FHA domain (domain), MAD homology, MH1 (domain), Interferon regulatory factor-3 (domain)
Ensembl Family MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4 FRAGMENT, MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4 MAD HOMOLOG 4 MOTHERS AGAINST DPP HOMOLOG 4 DELETION TARGET IN PANCREATIC CARCINOMA 4 SMAD FAMILY MEMBER 4 SMAD 4 SMAD4
Ensembl Gene ENSG00000141646
Entrez 4089
UniProt B4DZP1, K7EIJ2, K7EIU8, K7EL15, K7EL18, K7ELK2, K7ENG1, K7ENG8, K7ES96, L7N2F7, Q13485, Q9BYG6
Gene Biotype protein_coding
Design Element 202526_at, 202527_s_at, 235725_at, 36953_at, 3788303, 3788304, 3788305, 3788306, 3788307, 3788308, 3788312, 3788314, 3788315, 3788316, 3788318, 3788319, 3788320, 3788321, 3788322, 3788323, 3788324, 3788325, 3788327, 3788328, 3788330, 3788335, 3788337, 3788344, 3788345, 3788346, 3788347, 3788348, 3788349, 3788350, 3788351, 3788353, 3788355, 3788357, 3788358, 3788359, 46885_at, 509_at, 510_g_at, 57902_at, 58962_at, 74813_at, 8021228, A_19_P00323665, A_19_P00804817, A_19_P00812250, A_23_P27346, Hs.50438.0.A1_3p_at, Hs.75862.0.S2_3p_at, U44378_at, g4885456_3p_a_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 33 results
Showing 33 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0