Expression Atlas results for ENSG00000140464

    PML Homo sapiens promyelocytic leukemia
Synonyms MYL, RNF71, TRIM19
Orthologs PML (Bos taurus), PML (Canis familiaris), PML (Equus caballus), ENSGALG00000001398 (Gallus gallus), ENSGALG00000001478 (Gallus gallus), PML (Macaca mulatta), Pml (Mus musculus), Pml (Rattus norvegicus), PML (Sus scrofa)
Gene Ontology protein binding transcription factor activity, response to hypoxia, regulation of protein phosphorylation, positive regulation of defense response to virus by host, immune system process, molecular function, DNA binding, transcription coactivator activity, protein binding, cellular component, intracellular, nucleus, nucleoplasm, nucleolus, cytoplasm, endosome, cytosol, transcription, DNA-templated, regulation of transcription, DNA-templated, protein complex assembly, protein targeting, transport, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process, response to stress, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, cell cycle arrest, signal transduction, transforming growth factor beta receptor signaling pathway, common-partner SMAD protein phosphorylation, SMAD protein import into nucleus, aging, cell aging, biological process, cell death, zinc ion binding, negative regulation of cell proliferation, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to oxidative stress, catabolic process, biosynthetic process, response to UV, response to gamma radiation, regulation of calcium ion transport into cytosol, viral process, nuclear matrix, negative regulation of angiogenesis, PML body, cytokine-mediated signaling pathway, enzyme binding, cellular component assembly, myeloid cell differentiation, negative regulation of cell growth, PML body organization, positive regulation of histone deacetylation, ubiquitin protein ligase binding, nuclear membrane, small conjugating protein binding, SUMO binding, negative regulation of telomere maintenance via telomerase, endoplasmic reticulum calcium ion homeostasis, circadian regulation of gene expression, negative regulation of translation in response to oxidative stress, response to cytokine, cellular nitrogen compound metabolic process, extrinsic component of endoplasmic reticulum membrane, homeostatic process, regulation of circadian rhythm, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, protein homodimerization activity, entrainment of circadian clock by photoperiod, proteasome-mediated ubiquitin-dependent protein catabolic process, ion binding, organelle, symbiosis, encompassing mutualism through parasitism, innate immune response, cell fate commitment, regulation of MHC class I biosynthetic process, negative regulation of transcription, DNA-templated, negative regulation of mitotic cell cycle, SMAD binding, protein heterodimerization activity, retinoic acid receptor signaling pathway, protein stabilization, cobalt ion binding, maintenance of protein location in nucleus, defense response to virus, negative regulation of telomerase activity, positive regulation of apoptotic process involved in mammary gland involution, interferon-gamma-mediated signaling pathway, branching involved in mammary gland duct morphogenesis, macromolecular complex assembly, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, cellular response to interleukin-4, intrinsic apoptotic signaling pathway by p53 class mediator, cellular senescence, extrinsic apoptotic signaling pathway, negative regulation of viral release from host cell, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of double-strand break repair, positive regulation of apoptotic signaling pathway, positive regulation of extrinsic apoptotic signaling pathway
InterPro Zinc finger, B-box (domain), Zinc finger, RING-type (domain), Protein of unknown function DUF3583 (family)
Ensembl Family PML
Ensembl Gene ENSG00000140464
Entrez 5371
UniProt H3BRN3, H3BT57, P29590, Q05835, Q59H09, Q9UE85
Gene Biotype protein_coding
Design Element 206503_x_at, 210362_x_at, 211012_s_at, 211013_x_at, 211014_s_at, 211588_s_at, 235508_at, 239582_at, 3601388, 3601389, 3601390, 3601392, 3601393, 3601394, 3601395, 3601401, 3601403, 3601404, 3601405, 3601406, 3601407, 3601408, 3601409, 3601410, 3601411, 3601412, 3601413, 3601414, 3601415, 3601416, 3601417, 3601418, 3601419, 3601420, 3601421, 3601422, 3601423, 3601424, 3601425, 3601426, 3601427, 3601428, 3601429, 3601430, 3601435, 3601436, 3601437, 3601438, 3601439, 3601440, 3601441, 3601442, 3601443, 3601445, 3601447, 3601449, 3601450, 3601451, 38787_at, 38788_at, 48964_at, 566_at, 567_s_at, 7984779, A_23_P306148, A_23_P334664, A_23_P358944, A_24_P133542, A_24_P198598, A_24_P207139, Hs.258217.0.A1_3p_at, Hs.97255.0.A1_3p_at, M79462_at, M79463_s_at, X63131_s_at, g12275906_3p_s_at, g12275908_3p_s_at, g190116_3p_at, g4505902_3p_a_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 36 results
Showing 36 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0