Expression Atlas results for ENSG00000116288

    PARK7 Homo sapiens parkinson protein 7
Synonyms DJ-1, DJ1
Orthologs PARK7 (Bos taurus), PARK7 (Canis familiaris), ENSCING00000003618, ENSCSAVG00000003686 (Ciona savignyi), park7 (Danio rerio), PARK7 (Equus caballus), DJ-1 (Gallus gallus), PARK7 (Macaca mulatta), Park7 (Mus musculus), Park7 (Rattus norvegicus), LOC365828 (Rattus norvegicus), PARK7 (Sus scrofa), park7 (Xenopus tropicalis), DJ-1alpha (Drosophila melanogaster), dj-1beta (Drosophila melanogaster), djr-1.1 (Caenorhabditis elegans), djr-1.2 (Caenorhabditis elegans)
Gene Ontology chromatin, protein binding transcription factor activity, negative regulation of protein phosphorylation, synaptic transmission, dopaminergic, molecular function, transcription coactivator activity, RNA binding, mRNA binding, receptor binding, protein binding, cellular component, nucleus, cytoplasm, mitochondrion, mitochondrial respiratory chain complex I, mitochondrial intermembrane space, mitochondrial matrix, cytosol, plasma membrane, negative regulation of protein kinase activity, proteolysis, autophagy, response to stress, inflammatory response, mitochondrion organization, signal transduction, Ras protein signal transduction, single fertilization, transcription factor binding, biological process, peptidase activity, adult locomotory behavior, catabolic process, biosynthetic process, positive regulation of gene expression, negative regulation of gene expression, oxidoreductase activity, superoxide dismutase copper chaperone activity, PML body, oxidoreductase activity, acting on peroxide as acceptor, lyase activity, enzyme active site formation via L-cysteine sulfinic acid, glyoxalase III activity, methylglyoxal catabolic process to D-lactate, lactate biosynthetic process, enzyme binding, cytokine binding, enzyme regulator activity, axon, negative regulation of protein ubiquitination, negative regulation of protein binding, activation of protein kinase B activity, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of interleukin-8 production, positive regulation of peptidyl-serine phosphorylation, negative regulation of protein sumoylation, cellular response to oxidative stress, cellular response to reactive oxygen species, negative regulation of protein catabolic process, response to hydrogen peroxide, hydrogen peroxide metabolic process, identical protein binding, protein homodimerization activity, neuron projection, negative regulation of apoptotic process, ion binding, organelle, protein complex, regulation of neuron apoptotic process, negative regulation of neuron apoptotic process, small molecule metabolic process, cell body, small protein activating enzyme binding, small protein conjugating enzyme binding, positive regulation of transcription from RNA polymerase II promoter, glycolate biosynthetic process, negative regulation of protein export from nucleus, androgen receptor binding, regulation of inflammatory response, protein stabilization, positive regulation of sequence-specific DNA binding transcription factor activity, negative regulation of ubiquitin-protein transferase activity, dopamine uptake involved in synaptic transmission, regulation of mitochondrial membrane potential, positive regulation of protein kinase B signaling, membrane depolarization, peroxiredoxin activity, oxidation-reduction process, membrane hyperpolarization, negative regulation of cell death, regulation of androgen receptor signaling pathway, extracellular vesicular exosome, cellular response to hydrogen peroxide, repressing transcription factor binding, positive regulation of protein homodimerization activity, scaffold protein binding, positive regulation of protein localization to nucleus, negative regulation of neuron death, positive regulation of superoxide dismutase activity, negative regulation of protein acetylation, regulation of fibril organization, positive regulation of mitochondrial electron transport, NADH to ubiquinone, negative regulation of death-inducing signaling complex assembly, negative regulation of protein K48-linked deubiquitination, negative regulation of TRAIL-activated apoptotic signaling pathway, cupric ion binding, cuprous ion binding, positive regulation of pyrroline-5-carboxylate reductase activity, ubiquitin-specific protease binding, negative regulation of ubiquitin-specific protease activity, positive regulation of oxidative phosphorylation uncoupler activity, positive regulation of transcription regulatory region DNA binding, positive regulation of androgen receptor activity, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
InterPro ThiJ/PfpI (domain), DJ-1 (family), Class I glutamine amidotransferase-like (domain)
Ensembl Family DJ 1 PRECURSOR EC_3.4.-.- PARKINSON DISEASE 7 HOMOLOG
Ensembl Gene ENSG00000116288
Entrez 102724203, 11315
UniProt K7ELW0, K7EN27, Q99497, V9HWC2
Gene Biotype protein_coding
Design Element 200006_at, 2318737, 2318738, 2318739, 2318740, 2318741, 2318743, 2318744, 2318745, 2318746, 2318747, 2318748, 2318749, 2318751, 2318753, 2318754, 2318755, 2318756, 2318757, 2318775, 2318815, 2318871, 38974_at, 7893721, 7893831, 7893952, 7894579, 7895627, 7895911, 7896108, 7896422, 7896468, 7897404, A_23_P74740, A_33_P3231981, D61380_at, g6005748_3p_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 20 results
Showing 20 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0