Expression Atlas results for ENSG00000089041

    P2RX7 Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms MGC20089, P2X7
Orthologs P2RX7 (Bos taurus), P2RX7 (Canis familiaris), p2rx7 (Danio rerio), P2RX7 (Equus caballus), P2RX7 (Gallus gallus), P2RX7 (Macaca mulatta), P2rx7 (Mus musculus), P2rx7 (Rattus norvegicus), P2X7R (Sus scrofa), P2RX7 (Xenopus tropicalis)
Gene Ontology activation of MAPK activity, magnesium ion binding, cell morphogenesis, lipopolysaccharide binding, purinergic nucleotide receptor activity, phagolysosome assembly, positive regulation of T cell mediated cytotoxicity, positive regulation of protein phosphorylation, regulation of sodium ion transport, receptor activity, extracellular ATP-gated cation channel activity, receptor binding, ion channel activity, copper ion binding, protein binding, ATP binding, integral component of nuclear inner membrane, cytoplasm, plasma membrane, integral component of plasma membrane, cell-cell junction, protein phosphorylation, membrane protein ectodomain proteolysis, phospholipid transfer to membrane, ion transport, cation transport, calcium ion transport, cell volume homeostasis, membrane budding, inflammatory response, mitochondrion organization, plasma membrane organization, cell surface receptor signaling pathway, zinc ion binding, response to mechanical stimulus, response to bacterium, external side of plasma membrane, response to organic substance, response to zinc ion, gene expression, positive regulation of calcium ion transport into cytosol, programmed cell death, positive regulation of glutamate secretion, positive regulation of gamma-aminobutyric acid secretion, response to organic cyclic compound, channel activity, membrane, synaptic vesicle exocytosis, protein processing, neuronal action potential, sensory perception of pain, cytolysis, positive regulation of bone mineralization, neuromuscular junction, cellular response to extracellular stimulus, bleb, bleb assembly, positive regulation of prostaglandin secretion, response to lipopolysaccharide, positive regulation of interleukin-1 beta production, positive regulation of interleukin-6 production, collagen metabolic process, response to ATP, ion transmembrane transport, response to fluid shear stress, purinergic nucleotide receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, T cell proliferation, response to drug, protein homodimerization activity, neuron projection, neuronal cell body, T cell homeostasis, positive regulation of apoptotic process, positive regulation of catalytic activity, NAD transport, terminal bouton, protein complex, negative regulation of MAPK cascade, positive regulation of MAPK cascade, multicellular organismal protein catabolic process, innate immune response, membrane raft, synapse, phospholipid translocation, positive regulation of ossification, negative regulation of bone resorption, positive regulation of cytolysis, ceramide biosynthetic process, pore complex assembly, skeletal system morphogenesis, homeostasis of number of cells within a tissue, positive regulation of protein secretion, positive regulation of cytokine secretion, positive regulation of interleukin-1 alpha secretion, positive regulation of interleukin-1 beta secretion, defense response to Gram-positive bacterium, release of sequestered calcium ion into cytosol, protein oligomerization, positive regulation of cytoskeleton organization, response to calcium ion, response to electrical stimulus, regulation of killing of cells of other organism, membrane depolarization, positive regulation of mitochondrial depolarization, transmembrane transport, positive regulation of lymphocyte apoptotic process, reactive oxygen species metabolic process, scaffold protein binding, apoptotic signaling pathway, extrinsic apoptotic signaling pathway
InterPro P2X purinoreceptor (family), P2X7 purinoceptor (family)
Ensembl Gene ENSG00000089041
Entrez 5027
UniProt B3KR29, F5H237, F5H2X6, F5H8E7, J3KN30, K4K1I8, Q99572
Gene Biotype protein_coding
Design Element 207091_at, 230741_at, 3091987, 33697_at, 3434727, 3434728, 3434731, 3434733, 3434734, 3434735, 3434736, 3434739, 3434741, 3434742, 3434743, 3434744, 3434745, 3434746, 3434747, 3434749, 3434750, 3434752, 3434753, 3434755, 3434757, 3471107, 51015_at, 7959251, A_23_P25354, A_24_P319113, A_32_P30004, A_33_P3263867, Hs.41322.0.A1_3p_at, Y09561_at, g4505552_3p_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 7 results
Showing 7 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0