Expression Atlas results for ENSG00000073756

    PTGS2 Homo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms COX2
Orthologs PGHS-2 (Bos taurus), PTGS2 (Canis familiaris), ENSCING00000006154, ENSCING00000006498 (Ciona intestinalis), ENSCSAVG00000000436 (Ciona savignyi), ENSCSAVG00000009717 (Ciona savignyi), ptgs2a (Danio rerio), ptgs2b (Danio rerio), PTGS2 (Equus caballus), PTGS2 (Gallus gallus), PTGS2 (Macaca mulatta), Ptgs2 (Mus musculus), Ptgs2 (Rattus norvegicus), ptgs2 (Xenopus tropicalis)
Gene Ontology prostaglandin biosynthetic process, angiogenesis, peroxidase activity, prostaglandin-endoperoxide synthase activity, protein binding, nucleus, cytoplasm, endoplasmic reticulum membrane, prostaglandin metabolic process, cellular component movement, inflammatory response, response to oxidative stress, embryo implantation, learning, memory, regulation of blood pressure, negative regulation of cell proliferation, lipid binding, response to radiation, response to fructose, response to organic substance, response to manganese ion, response to lithium ion, response to organonitrogen compound, positive regulation vascular endothelial growth factor production, positive regulation of cell death, response to organic cyclic compound, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, sensory perception of pain, arachidonic acid metabolic process, cyclooxygenase pathway, lipoxygenase pathway, enzyme binding, heme binding, bone mineralization, ovulation, positive regulation of prostaglandin biosynthetic process, positive regulation of fever generation, positive regulation of synaptic plasticity, negative regulation of synaptic transmission, dopaminergic, response to estradiol, response to lipopolysaccharide, response to vitamin D, response to cytokine, response to tumor necrosis factor, cellular response to UV, maintenance of blood-brain barrier, regulation of cell proliferation, positive regulation of NF-kappaB import into nucleus, response to drug, hair cycle, anagen, protein homodimerization activity, neuron projection, positive regulation of apoptotic process, protein complex, small molecule metabolic process, positive regulation of nitric oxide biosynthetic process, negative regulation of cell cycle, positive regulation of vasoconstriction, negative regulation of smooth muscle contraction, positive regulation of smooth muscle contraction, decidualization, metal ion binding, positive regulation of smooth muscle cell proliferation, arachidonate 15-lipoxygenase activity, regulation of inflammatory response, brown fat cell differentiation, response to glucocorticoid, negative regulation of calcium ion transport, positive regulation of synaptic transmission, glutamatergic, oxidation-reduction process, response to fatty acid, cellular response to mechanical stimulus, cellular response to ATP, cellular response to hypoxia, positive regulation of transforming growth factor beta production, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of fibroblast growth factor production, positive regulation of brown fat cell differentiation, positive regulation of platelet-derived growth factor production
InterPro Epidermal growth factor-like domain (domain), Haem peroxidase, animal (family), Haem peroxidase (family), Haem peroxidase, animal, subgroup (family)
Ensembl Family PROSTAGLANDIN G/H SYNTHASE 2 PRECURSOR EC_1.14.99.1 CYCLOOXYGENASE 2 COX 2 PHS II PROSTAGLANDIN H2 SYNTHASE 2 PGH SYNTHASE 2 PGHS 2 PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2
Ensembl Gene ENSG00000073756
Entrez 5743
UniProt D9MWI3, P35354, Q6ZYK7
Gene Biotype protein_coding
Design Element 1069_at, 1554997_a_at, 204748_at, 2448383, 2448384, 2448385, 2448386, 2448387, 2448389, 2448390, 2448391, 2448392, 2448393, 2448394, 2448395, 2448396, 2448397, 2448398, 2448399, 2448400, 2448401, 2448402, 2448403, 7922976, A_24_P250922, A_24_P77008, D28235_s_at, Hs2.196384.2.S1_3p_s_at, L15326_s_at, U04636_rna1_at, g4506264_3p_at, g4506264_3p_x_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 98 results
Showing 50 of 98 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0