Expression Atlas results for ENSG00000069869

    NEDD4 Homo sapiens neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
Synonyms KIAA0093, MGC176705, NEDD4-1, RPF1
Orthologs NEDD4 (Bos taurus), NEDD4 (Canis familiaris), ENSCING00000003020, ENSCSAVG00000004819 (Ciona savignyi), NEDD4 (Danio rerio), NEDD4 (Equus caballus), NEDD4 (Gallus gallus), NEDD4 (Macaca mulatta), Nedd4 (Mus musculus), Nedd4 (Rattus norvegicus), NEDD4 (Sus scrofa), nedd4 (Xenopus tropicalis), Nedd4 (Drosophila melanogaster), Y92H12A.2 (Caenorhabditis elegans), RSP5 (Saccharomyces cerevisiae)
Gene Ontology negative regulation of transcription from RNA polymerase II promoter, ubiquitin ligase complex, chromatin, adaptive immune response, outflow tract morphogenesis, endocardial cushion development, ubiquitin-protein transferase activity, protein binding, nucleus, cytoplasm, Golgi apparatus, cytosol, plasma membrane, cell cortex, protein monoubiquitination, protein targeting to lysosome, lysosomal transport, neuromuscular junction development, negative regulation of sodium ion transport, negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage, positive regulation of phosphatidylinositol 3-kinase signaling, membrane, apicolateral plasma membrane, protein ubiquitination, ligase activity, transmission of virus, cytokine-mediated signaling pathway, sodium channel inhibitor activity, protein domain specific binding, negative regulation of vascular endothelial growth factor receptor signaling pathway, neuron projection development, receptor internalization, beta-2 adrenergic receptor binding, receptor catabolic process, cellular response to UV, regulation of ion transmembrane transport, T cell activation, regulation of membrane potential, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, glucocorticoid receptor signaling pathway, ubiquitin binding, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, development involved in symbiotic interaction, positive regulation of protein catabolic process, positive regulation of nucleocytoplasmic transport, perinuclear region of cytoplasm, blood vessel morphogenesis, regulation of dendrite morphogenesis, regulation of synapse organization, phosphoserine binding, phosphothreonine binding, progesterone receptor signaling pathway, response to calcium ion, RNA polymerase binding, proline-rich region binding, protein K63-linked ubiquitination, regulation of potassium ion transmembrane transporter activity
InterPro C2 domain (domain), HECT (domain), WW domain (domain)
Ensembl Family E3 UBIQUITIN LIGASE EC_6.3.2.-, UNKNOWN
Ensembl Gene ENSG00000069869
Entrez 4734
UniProt P46934
Gene Biotype protein_coding
Design Element 213012_at, 32078_at, 3625540, 3625541, 3625542, 3625543, 3625544, 3625545, 3625547, 3625548, 3625549, 3625550, 3625551, 3625552, 3625554, 3625556, 3625558, 3625559, 3625560, 3625563, 3625564, 3625565, 3625566, 3625569, 3625572, 3625573, 3625575, 3625576, 3625577, 3625579, 3625582, 3625584, 3625598, 3625599, 3625600, 3625601, 3625602, 3625603, 3625604, 3625609, 3625610, 3625613, 3625614, 3625618, 3625619, 3625621, 3625622, 7989094, A_23_P331379, A_32_P160883, D42055_at, Hs.1565.0.S1_3p_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 24 results
Showing 24 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0