Expression Atlas results for ENSG00000017427

    IGF1 Homo sapiens insulin-like growth factor 1 (somatomedin C)
Synonyms IGF1A
Orthologs IGF-I (Bos taurus), IGF1 (Canis familiaris), igf1 (Danio rerio), IGF1 (Equus caballus), IGF-I (Gallus gallus), IGF1 (Macaca mulatta), Igf1 (Mus musculus), Igf1 (Rattus norvegicus), IGFI (Sus scrofa), igf1 (Xenopus tropicalis)
Gene Ontology skeletal system development, cell activation, regulation of protein phosphorylation, blood vessel remodeling, platelet degranulation, insulin receptor binding, insulin-like growth factor receptor binding, integrin binding, hormone activity, protein binding, extracellular region, extracellular space, plasma membrane, DNA replication, cellular component movement, signal transduction, Ras protein signal transduction, nervous system development, muscle organ development, blood coagulation, growth factor activity, positive regulation of cell proliferation, negative regulation of cell proliferation, glycolate metabolic process, glial cell differentiation, positive regulation of cardiac muscle hypertrophy, positive regulation of phosphatidylinositol 3-kinase signaling, satellite cell maintenance involved in skeletal muscle regeneration, muscle hypertrophy, myotube cell development, positive regulation of smooth muscle cell migration, insulin-like growth factor binding protein complex, positive regulation of cerebellar granule cell precursor proliferation, water homeostasis, proteoglycan biosynthetic process, platelet activation, lung development, mammary gland development, exocrine pancreas development, platelet alpha granule lumen, regulation of establishment or maintenance of cell polarity, positive regulation of protein import into nucleus, translocation, negative regulation of smooth muscle cell apoptotic process, multicellular organism growth, bone mineralization involved in bone maturation, regulation of multicellular organism growth, positive regulation of activated T cell proliferation, positive regulation of tyrosine phosphorylation of Stat5 protein, negative regulation of apoptotic process, positive regulation of DNA binding, positive regulation of MAPK cascade, positive regulation of insulin-like growth factor receptor signaling pathway, cellular protein metabolic process, myoblast differentiation, positive regulation of osteoblast differentiation, positive regulation of glycogen biosynthetic process, positive regulation of DNA replication, positive regulation of glycolytic process, positive regulation of mitosis, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, positive regulation of glucose import, positive regulation of Ras protein signal transduction, insulin-like growth factor receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of fibroblast proliferation, lung alveolus development, cell development, positive regulation of smooth muscle cell proliferation, branching morphogenesis of an epithelial tube, inner ear development, chondroitin sulfate proteoglycan biosynthetic process, positive regulation of epithelial cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of protein metabolic process, myoblast proliferation, positive regulation of protein kinase B signaling, lung vasculature development, lung lobe morphogenesis, Type I pneumocyte differentiation, Type II pneumocyte differentiation, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate gland growth, prostate gland epithelium morphogenesis, prostate gland stromal morphogenesis, negative regulation of androgen receptor signaling pathway, negative regulation of ERK1 and ERK2 cascade, positive regulation of calcineurin-NFAT signaling cascade, negative regulation of release of cytochrome c from mitochondria, extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of myoblast proliferation, negative regulation of extrinsic apoptotic signaling pathway
InterPro Insulin-like (domain), Insulin-like growth factor I (family), Insulin-like growth factor (family), Insulin family (family)
Ensembl Family INSULIN GROWTH FACTOR I PRECURSOR IGF I SOMATOMEDIN
Ensembl Gene ENSG00000017427
Entrez 3479
UniProt P05019, Q13429, Q59GC5, Q5U743, Q6LD41, Q9NP10
Gene Biotype protein_coding
Design Element 1501_at, 1625_at, 1975_s_at, 209540_at, 209541_at, 209542_x_at, 211577_s_at, 3468346, 3468347, 3468348, 3468350, 3468351, 3468353, 3468354, 3468372, 3468377, 3468378, 38737_at, 64305_s_at, 7965873, A_23_P13907, A_24_P304419, A_24_P304423, A_24_P398572, Hs.85112.0.S2_3p_at, Hs.85112.0.S3_3p_at, X57025_at, g184833_3p_a_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 21 results
Showing 21 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0