Expression Atlas results for ENSG00000012048

    BRCA1 Homo sapiens breast cancer 1, early onset
Synonyms BRCC1, PPP1R53, RNF53
Orthologs BRCA1 (Bos taurus), BRCA1 (Canis familiaris), ENSCING00000010053 (Ciona intestinalis), ENSCSAVG00000006376 (Ciona savignyi), BRCA1 (Equus caballus), BRCA1 (Gallus gallus), BRCA1 (Macaca mulatta), Brca1 (Mus musculus), Brca1 (Rattus norvegicus), BRCA1 (Sus scrofa), brca1 (Xenopus tropicalis)
Gene Ontology ubiquitin ligase complex, double-strand break repair via homologous recombination, condensed chromosome, condensed nuclear chromosome, ruffle, DNA binding, damaged DNA binding, transcription coactivator activity, RNA binding, ubiquitin-protein transferase activity, protein binding, nucleus, nucleoplasm, chromosome, cytoplasm, plasma membrane, focal adhesion, DNA replication, DNA repair, postreplication repair, double-strand break repair, regulation of gene expression by genetic imprinting, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase III promoter, fatty acid biosynthetic process, apoptotic process, cellular response to DNA damage stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, chromosome segregation, centrosome cycle, zinc ion binding, gamma-tubulin ring complex, intrinsic apoptotic signaling pathway in response to DNA damage, dosage compensation by inactivation of X chromosome, response to ionizing radiation, tubulin binding, protein ubiquitination, ligase activity, enzyme binding, androgen receptor signaling pathway, ribonucleoprotein complex, positive regulation of protein ubiquitination, BRCA1-BARD1 complex, G2 DNA damage checkpoint, ubiquitin protein ligase binding, filamentous actin, substrate adhesion-dependent cell spreading, positive regulation of histone acetylation, negative regulation of histone acetylation, regulation of cell proliferation, regulation of apoptotic process, chordate embryonic development, protein complex, response to estrogen, regulation of DNA methylation, transcription regulatory region DNA binding, negative regulation of fatty acid biosynthetic process, positive regulation of DNA repair, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, negative regulation of centriole replication, metal ion binding, androgen receptor binding, positive regulation of histone H3-K4 methylation, negative regulation of histone H3-K4 methylation, negative regulation of histone H3-K9 methylation, positive regulation of histone H3-K9 methylation, protein autoubiquitination, positive regulation of histone H4-K20 methylation, BRCA1-A complex, positive regulation of cell cycle arrest, cellular response to indole-3-methanol, protein K6-linked ubiquitination, regulation of cell motility, positive regulation of histone H3-K9 acetylation, positive regulation of histone H4-K16 acetylation
InterPro BRCT domain (domain), Zinc finger, RING-type (domain), Breast cancer type 1 susceptibility protein (BRCA1) (family), Zinc finger, C3HC4 RING-type (domain)
Ensembl Family BREAST CANCER TYPE 1 SUSCEPTIBILITY HOMOLOG EC_6.3.2.-, UNKNOWN
Ensembl Gene ENSG00000012048
Entrez 672
UniProt B4DES0, B7ZA85, C4PFY7, C6YB45, C9IZW4, E7ENB7, E7EP70, E7EQW4, E7EUM2, E7EWN5, E9PC22, E9PFC7, E9PFZ0, E9PH68, G1UI37, G4V4Z7, G4V4Z8, G4V500, G4V502, G4V503, H0Y881, H0Y8B8, K4JUB1, K4JXS7, K4K7U9, K4K7V3, K7EJW3, K7EPC7, P38398, Q3B891, Q3LRH8, Q3YB49, Q3YB50, Q3YB53, Q4EW25, Q5YLB2, Q7KYU6, Q92897, Q9NQR3, Q9UE29
Gene Biotype protein_coding
Design Element 1993_s_at, 204531_s_at, 211851_x_at, 2395433, 33724_at, 3506844, 3758316, 3758318, 3758319, 3758321, 3758323, 3758324, 3758334, 3758335, 3758337, 3758339, 3758340, 3758341, 3758342, 3758344, 3758345, 3758350, 3758351, 3758355, 3758356, 3758357, 3758358, 3758359, 3758360, 3758361, 3758362, 3758363, 3758364, 3758366, 3758367, 3758368, 3758369, 3758370, 3758371, 3758372, 3758373, 3758374, 3758375, 3758395, 604_at, 69578_at, 8015769, A_23_P207400, A_32_P171695, L78833_cds1_at, U64805_s_at, g2218153_3p_a_at, g6552300_3p_a_at
    Baseline Expression Results in tissues
c Expression Level cut-off: 0.5
    Differential Expression 40 results
Showing 40 results cutoffs: adjusted p-value 0.05    log2-fold change 1.0