MAP3K7
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Homo sapiens |
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MAP3K7 is differentially expressed in 313 experiments: 140 organism parts: liver, bone marrow, ... (138 more);, 248 disease states: normal, prostate carcinoma, ... (246 more);, 107 cell types 458 cell lines 43 compound treatments and 85 other conditions. |
| Synonyms |
TAK1, MEKK7 |
| Orthologs |
Map3k7
(Mus musculus)
E1C063_CHICK
(Gallus gallus)
map3k7
(Danio rerio)
Map3k7
(Rattus norvegicus)
M3K7_BOVIN
(Bos taurus)
F6PZN7_CIOIN
(Ciona intestinalis)
Takl2
(Drosophila melanogaster)
Tak1
(Drosophila melanogaster)
map3k7
(Xenopus laevis)
MAP3K7
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR020635, IPR017421 |
| Gene Ontology Term |
angiogenesis, Toll signaling pathway, cytosol, protein binding, MAP kinase kinase kinase activity, innate immune response, negative regulation of apoptosis, MAPKKK cascade, protein tyrosine kinase activity, transforming growth factor beta receptor signaling pathway, MAP kinase kinase activity, stress-activated MAPK cascade, endosome membrane, positive regulation of JUN kinase activity, positive regulation of JNK cascade, activation of MAPK activity, I-kappaB kinase/NF-kappaB cascade, activation of MAPKK activity, ATP binding, magnesium ion binding, transferase activity, transferring phosphorus-containing groups, nucleotide binding, kinase activity, histone H3 acetylation, protein serine/threonine kinase activity, JNK cascade, positive regulation of NF-kappaB transcription factor activity, signal transduction, protein kinase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, toll-like receptor 4 signaling pathway, T cell receptor signaling pathway, positive regulation of T cell activation, neural tube formation, toll-like receptor signaling pathway, activation of innate immune response, positive regulation of interleukin-2 production, positive regulation of T cell cytokine production, toll-like receptor 3 signaling pathway, activation of NF-kappaB-inducing kinase activity, toll-like receptor 2 signaling pathway, MyD88-dependent toll-like receptor signaling pathway, IkappaB kinase complex, I-kappaB phosphorylation, protein phosphorylation, MyD88-independent toll-like receptor signaling pathway, Ada2/Gcn5/Ada3 transcription activator complex, toll-like receptor 1 signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway |
| Ensembl Family |
ENSFM00380000124721 |
| Gene Ontology ID |
GO:0008063, GO:0007179, GO:0007165, GO:0007249, GO:0007254, GO:0010008, GO:0016301, GO:0051403, GO:0051092, GO:0016772, GO:0004709, GO:0004708, GO:0004713, GO:0043966, GO:0005524, GO:0005515, GO:0005829, GO:0004672, GO:0004674, GO:0046330, GO:0043066, GO:0006468, GO:0000165, GO:0000166, GO:0000187, GO:0000186, GO:0000287, GO:0043507, GO:0001525, GO:0045087, GO:0008385, GO:0034142, GO:0034138, GO:0034134, GO:0007250, GO:0007252, GO:0002755, GO:0002726, GO:0002218, GO:0002224, GO:0043123, GO:0032743, GO:0050870, GO:0050852, GO:0001841, GO:0002756, GO:0005671, GO:0034130, GO:0070423 |
| InterPro Term |
Prot_kinase_cat_dom, MAPKKK7, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family Description |
MITOGEN ACTIVATED KINASE KINASE KINASE 7 EC_2.7.11.25 TGF BETA ACTIVATED KINASE 1 |
| EMBL-Bank ID |
AB009357, AB009356, AB009358, AL050393, BC017715, AK315774, CH471051, AF218074, AL121837, AL121964, DQ314875 |
| RefSeq ID |
NM_003188, NM_145331, NM_145333, NM_145332, NP_003179, NP_663306, NP_663304, NP_663305 |
| Ensembl Gene ID |
ENSG00000135341 |
| UniProt Accession |
Q9NZ70, Q9UG54, O43318, E7EMD4 |
| Entrez Gene ID |
6885 |
| HGNC Symbol |
MAP3K7 |
| Ensembl Protein ID |
ENSP00000400470, ENSP00000358331, ENSP00000358333, ENSP00000358335, ENSP00000358338, ENSP00000358326 |
| Description |
mitogen-activated protein kinase kinase kinase 7 [Source:HGNC Symbol;Acc:6859] |
| UniGene ID |
Hs.731065 |
| Ensembl Transcript ID |
ENST00000369332, ENST00000369329, ENST00000369327, ENST00000369320, ENST00000369325, ENST00000450832, ENST00000479630 |
| Design Element |
ENST00000479630, g4507360_3p_a_at, 211536_x_at, 53270_s_at, 86022_at, ENST00000369332, ENST00000450832, 211537_x_at, ENST00000369320, 43794_at, 206854_s_at, ENST00000369325, 206853_s_at, g8978251_3p_a_at, ENST00000369327, 36905_at, ENST00000369329, Hs.7510.0.S2_3p_a_at |
| Search EB-eye |
ENSG00000135341
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