SFRP1
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Homo sapiens |
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SFRP1 is differentially expressed in 318 experiments: 177 organism parts: lung, liver, ... (175 more);, 217 disease states: normal, glioblastoma, ... (215 more);, 99 cell types 455 cell lines 37 compound treatments and 73 other conditions. |
| Synonyms |
FRP-1, SARP2, FRP |
| Orthologs |
Sfrp1
(Mus musculus)
sfrp1b
(Danio rerio)
SFRP1
(Gallus gallus)
Q4H2U5_CIOIN
(Ciona intestinalis)
SFRP1
(Bos taurus)
sfrp1a
(Danio rerio)
Sfrp1
(Rattus norvegicus)
sfrp1
(Xenopus laevis)
SFRP1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008201, GO:0010629, GO:0009952, GO:0009950, GO:0008285, GO:0008284, GO:0009986, GO:0060070, GO:0060071, GO:0008406, GO:0009790, GO:0008585, GO:0008584, GO:0007420, GO:0042493, GO:0030514, GO:0004197, GO:0048546, GO:0042813, GO:0042802, GO:0005622, GO:0005615, GO:0005515, GO:0005576, GO:0005578, GO:0005886, GO:0005829, GO:0005109, GO:0050680, GO:0043065, GO:0043066, GO:0050732, GO:0031012, GO:0006309, GO:0001756, GO:0043508, GO:0045880, GO:0045892, GO:0045893, GO:0030165, GO:0030177, GO:0030178, GO:0030097, GO:0030308, GO:0030307, GO:0030336, GO:0035019, GO:0017147, GO:0010719, GO:0008144, GO:0060346, GO:0060687, GO:0060527, GO:0060218, GO:0014070, GO:0014034, GO:0002244, GO:0048147, GO:0050679, GO:0090090, GO:0001944, GO:0001954, GO:0090175, GO:0032855, GO:0045765, GO:0045600, GO:0045671, GO:0045668, GO:0051894, GO:0045578, GO:0001843, GO:0046546, GO:0051496, GO:0001657, GO:0001649, GO:0046676, GO:0021915, GO:0071456, GO:0071481, GO:0033689, GO:0022601, GO:0071392, GO:0071391, GO:0071305, GO:0071347, GO:0071356, GO:0071363, GO:0060766, GO:0030278, GO:0030279, GO:0009267, GO:0090246, GO:0090263, GO:0071504, GO:0071560, GO:0090244, GO:0010564, GO:0090179, GO:0046851, GO:0044345, GO:0044344, GO:0071380, GO:2000117, GO:0071773, GO:2000041, GO:2000080, GO:2000052, GO:2000054, GO:2000271, GO:2000270 |
| Gene Ontology Term |
cytosol, plasma membrane, negative regulation of cell growth, embryo development, frizzled binding, negative regulation of transcription, DNA-dependent, protein binding, digestive tract morphogenesis, negative regulation of peptidyl-tyrosine phosphorylation, intracellular, negative regulation of cell proliferation, extracellular space, Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of cell proliferation, heparin binding, proteinaceous extracellular matrix, negative regulation of apoptosis, male gonad development, extracellular region, somitogenesis, female gonad development, positive regulation of apoptosis, negative regulation of Wnt receptor signaling pathway, gonad development, identical protein binding, hemopoiesis, negative regulation of JUN kinase activity, cysteine-type endopeptidase activity, Wnt-protein binding, negative regulation of cell migration, negative regulation of BMP signaling pathway, positive regulation of smoothened signaling pathway, somatic stem cell maintenance, canonical Wnt receptor signaling pathway, response to drug, positive regulation of cell growth, DNA fragmentation involved in apoptotic nuclear change, cell surface, PDZ domain binding, negative regulation of epithelial cell proliferation, extracellular matrix, positive regulation of Wnt receptor signaling pathway, negative regulation of gene expression, brain development, positive regulation of transcription, DNA-dependent, dorsal/ventral axis specification, negative regulation of androgen receptor signaling pathway, development of primary male sexual characteristics, negative regulation of ossification, menstrual cycle phase, regulation of angiogenesis, positive regulation of focal adhesion assembly, negative regulation of fibroblast proliferation, cellular response to growth factor stimulus, cellular response to estradiol stimulus, neural tube closure, negative regulation of osteoblast proliferation, cellular response to hypoxia, negative regulation of osteoblast differentiation, negative regulation of osteoclast differentiation, negative regulation of epithelial to mesenchymal transition, drug binding, bone trabecula formation, negative regulation of B cell differentiation, positive regulation of canonical Wnt receptor signaling pathway, hemopoietic progenitor cell differentiation, regulation of ossification, osteoblast differentiation, negative regulation of insulin secretion, cellular response to estrogen stimulus, cellular response to transforming growth factor beta stimulus, positive regulation of epithelial cell proliferation, cellular response to heparin, positive regulation of stress fiber assembly, cellular response to vitamin D, cellular response to tumor necrosis factor, positive regulation of cell-matrix adhesion, vasculature development, neural crest cell fate commitment, regulation of branching involved in prostate gland morphogenesis, regulation of establishment of planar polarity, neural tube development, convergent extension involved in somitogenesis, hemopoietic stem cell differentiation, positive regulation of Rac GTPase activity, cellular response to X-ray, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, ureteric bud development, positive regulation of fat cell differentiation, cellular response to interleukin-1, cellular response to starvation, Wnt receptor signaling pathway involved in somitogenesis, regulation of cell cycle process, cellular response to prostaglandin E stimulus, negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation, stromal-epithelial cell signaling involved in prostate gland development, cellular response to BMP stimulus, negative regulation of planar cell polarity pathway involved in axis elongation, positive regulation of non-canonical Wnt receptor signaling pathway, negative regulation of bone remodeling, planar cell polarity pathway involved in neural tube closure, response to organic cyclic compound, cellular response to fibroblast growth factor stimulus, positive regulation of fibroblast apoptosis, negative regulation of cysteine-type endopeptidase activity, negative regulation of fibroblast apoptosis, negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification, Wnt-activated receptor activity, anterior/posterior pattern specification |
| InterPro ID |
IPR018933, IPR001134, IPR020067 |
| InterPro Term |
Netrin_domain, Netrin_module_non-TIMP, Frizzled_dom |
| Ensembl Family Description |
SECRETED FRIZZLED RELATED PRECURSOR SFRP |
| Ensembl Family |
ENSFM00600000921226 |
| EMBL-Bank ID |
BC036503, AK293090, AF017987, AK127331, AF001900, AF229191, AF229192, CH471080, AF056087, AC104393 |
| RefSeq ID |
NM_003012, NP_003003 |
| Ensembl Protein ID |
ENSP00000369174, ENSP00000220772, ENSP00000442829 |
| Entrez Gene ID |
6422 |
| UniProt Accession |
Q6ZSL4, A8KAM5, Q8N474, Q9BZZ6 |
| Ensembl Gene ID |
ENSG00000104332 |
| Description |
secreted frizzled-related protein 1 [Source:HGNC Symbol;Acc:10776] |
| HGNC Symbol |
SFRP1 |
| UniGene ID |
Hs.213424 |
| Ensembl Transcript ID |
ENST00000379845, ENST00000535263, ENST00000220772 |
| Design Element |
202037_s_at, ENST00000220772, ENST00000379845, 32521_at, Hs.7306.0.A1_3p_a_at, g2415416_3p_a_at, 202035_s_at, 202036_s_at, ENST00000535263, g8400731_3p_a_at |
| Search EB-eye |
ENSG00000104332
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