CTLA4
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Homo sapiens |
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CTLA4 is differentially expressed in 195 experiments: 88 organism parts: lung, bone marrow, ... (86 more);, 154 disease states: normal, cervical carcinoma, ... (152 more);, 67 cell types 151 cell lines 25 compound treatments and 72 other conditions. |
| Synonyms |
CD, CD152, CELIAC3, GSE, CD28, ICOS |
| Orthologs |
Q1XDY5_CHICK
(Gallus gallus)
Ctla4
(Mus musculus)
Q28090_BOVIN
(Bos taurus)
Ctla4
(Rattus norvegicus)
CD28
(Danio rerio)
CTLA4_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009897, GO:0016020, GO:0048471, GO:0006955, GO:0005886, GO:0005887, GO:0005794, GO:0006974, GO:0043065, GO:0030889, GO:0031295, GO:0050853, GO:0045590, GO:0045334 |
| InterPro Term |
Ig_V-set, Ig_sub, CTLA4, Ig_V-set_subgr |
| Gene Ontology Term |
plasma membrane, membrane, Golgi apparatus, positive regulation of apoptosis, external side of plasma membrane, integral to plasma membrane, immune response, perinuclear region of cytoplasm, response to DNA damage stimulus, B cell receptor signaling pathway, negative regulation of regulatory T cell differentiation, clathrin-coated endocytic vesicle, negative regulation of B cell proliferation, T cell costimulation |
| InterPro ID |
IPR013106, IPR003599, IPR003596, IPR008096 |
| Ensembl Family |
ENSFM00250000003550 |
| Ensembl Family Description |
CYTOTOXIC T LYMPHOCYTE 4 PRECURSOR CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4 CTLA 4 CD152 ANTIGEN |
| Gene-Disease Assocation |
HASHIMOTO THYROIDITIS, AUTOIMMUNE DISEASE, GRAVES DISEASE, HEPATITIS B VIRUS, SUSCEPTIBILITY TO, CELIAC DISEASE, SUSCEPTIBILITY TO, 3; CELIAC3, DIABETES MELLITUS, INSULIN-DEPENDENT, 12; IDDM12, SYSTEMIC LUPUS ERYTHEMATOSUS; SLE |
| RefSeq ID |
NP_001032720, NM_005214, NP_005205, NM_001037631 |
| UniProt Accession |
P16410, Q8TDA6, O95653, Q0Q5F1, Q9BZK2, E9L3G3, E9L3G1, E9L3G0 |
| EMBL-Bank ID |
BC074893, BC074842, AY999702, AY792514, L15006, U90273, M74363, AF411058, M37244, M37243, M37245, DQ534199, AF142144, AF414120, AC010138, AF316875, DQ357942, AF486806, HM545125, HM545126, HM545121, HM545124, DQ785106 |
| Ensembl Protein ID |
ENSP00000409707, ENSP00000303939, ENSP00000295854, ENSP00000417779, ENSP00000443262 |
| Entrez Gene ID |
1493 |
| Description |
cytotoxic T-lymphocyte-associated protein 4 [Source:HGNC Symbol;Acc:2505] |
| HGNC Symbol |
CTLA4 |
| UniGene ID |
Hs.247824 |
| Ensembl Gene ID |
ENSG00000163599 |
| Ensembl Transcript ID |
ENST00000487393, ENST00000541886, ENST00000302823, ENST00000295854, ENST00000427473, ENST00000472206 |
| Design Element |
ENST00000487393, Hs.313929.0.A1_3p_at, ENST00000295854, ENST00000302823, 231794_at, 234362_s_at, Hs.247824.2.S1_3p_a_at, ENST00000472206, M37245_at, 81915_at, ENST00000541886, 236341_at, ENST00000427473, 221331_x_at |
| Search EB-eye |
ENSG00000163599
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