PLCB1
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Homo sapiens |
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PLCB1 is differentially expressed in 317 experiments: 158 organism parts: amygdala, bone marrow, ... (156 more);, 207 disease states: normal, control, ... (205 more);, 105 cell types 437 cell lines 43 compound treatments and 85 other conditions. |
| Synonyms |
PLC154, PLC-I, KIAA0581 |
| Orthologs |
PLCB1
(Gallus gallus)
PLCB1 (2 of 2)
(Danio rerio)
Plcb1
(Rattus norvegicus)
Plcb1
(Mus musculus)
PLCB1_BOVIN
(Bos taurus)
PLCB1 (1 of 2)
(Danio rerio)
PLC1
(Saccharomyces cerevisiae)
Plc21C
(Drosophila melanogaster)
plcb1
(Xenopus laevis)
PLCB1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0048009, GO:0008277, GO:0016042, GO:0016607, GO:0007165, GO:0007268, GO:0051318, GO:0007612, GO:0007613, GO:0016787, GO:0000086, GO:0042803, GO:0005624, GO:0005521, GO:0005509, GO:0005516, GO:0005515, GO:0005546, GO:0004871, GO:0004435, GO:0005737, GO:0005634, GO:0005829, GO:0004629, GO:0046330, GO:0006629, GO:0046488, GO:0005096, GO:0000790, GO:0019899, GO:0043547, GO:0045892, GO:0045893, GO:0010243, GO:0007213, GO:0007215, GO:0048639, GO:0040019, GO:0032735, GO:0045663, GO:0043434, GO:0021987, GO:0070498, GO:0045444, GO:0035556, GO:0060466, GO:0080154, GO:0035724, GO:0035723, GO:0035722, GO:2000438, GO:2000344, GO:0034284 |
| Gene Ontology Term |
cytosol, negative regulation of transcription, DNA-dependent, protein binding, nuclear speck, cytoplasm, nuclear chromatin, memory, lamin binding, insulin-like growth factor receptor signaling pathway, membrane fraction, signal transducer activity, positive regulation of JNK cascade, learning, G1 phase, phospholipase C activity, calmodulin binding, GTPase activator activity, synaptic transmission, lipid metabolic process, nucleus, phosphatidylinositol-4,5-bisphosphate binding, G2/M transition of mitotic cell cycle, lipid catabolic process, regulation of G-protein coupled receptor protein signaling pathway, protein homodimerization activity, hydrolase activity, phosphatidylinositol metabolic process, enzyme binding, signal transduction, positive regulation of transcription, DNA-dependent, calcium ion binding, positive regulation of GTPase activity, positive regulation of embryonic development, response to organic nitrogen, positive regulation of myoblast differentiation, interleukin-1-mediated signaling pathway, cerebral cortex development, fat cell differentiation, positive regulation of interleukin-12 production, muscarinic acetylcholine receptor signaling pathway, glutamate signaling pathway, response to peptide hormone stimulus, positive regulation of developmental growth, intracellular signal transduction, phosphatidylinositol phospholipase C activity, CD24 biosynthetic process, regulation of fertilization, interleukin-12-mediated signaling pathway, activation of meiosis involved in egg activation, interleukin-15-mediated signaling pathway, positive regulation of acrosome reaction, negative regulation of monocyte extravasation, response to monosaccharide stimulus |
| InterPro ID |
IPR000008, IPR001192, IPR016280, IPR018029, IPR000909, IPR015359, IPR001711, IPR009535, IPR014815 |
| InterPro Term |
PLC-beta, PLC-beta_CS, C2_Ca-dep, PLipase_C_PInositol-sp_X_dom, C2_membr_targeting, PLC-beta_C, PLipase_C_EF-hand-like, Pinositol_PLipase_C, PLipase_C_Pinositol-sp_Y |
| Ensembl Family |
ENSFM00270000056436 |
| Ensembl Family Description |
1 PHOSPHATIDYLINOSITOL 4 5 BISPHOSPHATE PHOSPHODIESTERASE BETA EC_3.1.4.11 PHOSPHOINOSITIDE PHOSPHOLIPASE C BETA PHOSPHOLIPASE C BETA PLC BETA |
| Description |
phospholipase C, beta 1 (phosphoinositide-specific) [Source:HGNC Symbol;Acc:15917] |
| UniGene ID |
Hs.431173, Hs.608399, Hs.662314, Hs.628998 |
| Ensembl Protein ID |
ENSP00000367908, ENSP00000367904, ENSP00000391162, ENSP00000389911, ENSP00000396398, ENSP00000338185, ENSP00000384001, ENSP00000338402, ENSP00000431704, ENSP00000443413 |
| EMBL-Bank ID |
AL034551, AL050315, AL050323, BC069420, AL137267, AB011153, AJ278314, AJ278313, CH471133, BC117231, AY004175, AK023689, AL031683, AL049593, AL049632, AL445567, AL050319, AL365212, AL121589, AL021406, AL031655 |
| Entrez Gene ID |
23236 |
| UniProt Accession |
Q9NQ66, Q8IV91, Q8IV92, B1AK73, E9PEL1 |
| HGNC Symbol |
PLCB1 |
| RefSeq ID |
NP_056007, NP_877398, NM_015192, NM_182734 |
| Ensembl Gene ID |
ENSG00000182621 |
| Ensembl Transcript ID |
ENST00000475958, ENST00000404098, ENST00000494924, ENST00000437439, ENST00000441163, ENST00000378641, ENST00000378637, ENST00000439627, ENST00000535719, ENST00000338037, ENST00000338061, ENST00000487210 |
| Gene-Disease Assocation |
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 12; EIEE12 |
| Design Element |
ENST00000437439, g9438228_3p_a_at, ENST00000338037, Hs.41143.2.S1_3p_a_at, gnf1h05499_x_at, ENST00000338061, 81002_at, ENST00000404098, ENST00000439627, ENST00000487210, ENST00000475958, ENST00000535719, 35980_at, 42122_at, ENST00000494924, ENST00000378641, ENST00000441163, Hs.41143.0.S2_3p_at, ENST00000378637, 215687_x_at, 211925_s_at, 213222_at |
| Search EB-eye |
ENSG00000182621
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