CD8A
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Homo sapiens |
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CD8A is differentially expressed in 190 experiments: 74 organism parts: thymus, spleen, ... (72 more);, 149 disease states: normal, control, ... (147 more);, 86 cell types 146 cell lines 18 compound treatments and 60 other conditions. |
| Synonyms |
CD8 |
| Orthologs |
ENSGALG00000015900
(Gallus gallus)
A7MAZ7_BOVIN
(Bos taurus)
ENSGALG00000013492
(Gallus gallus)
CD8A
(Gallus gallus)
ENSGALG00000015852
(Gallus gallus)
Cd8a
(Mus musculus)
ENSGALG00000022939
(Gallus gallus)
Cd8a
(Rattus norvegicus)
LOC100489117
(Xenopus laevis)
CD8A_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009897, GO:0009986, GO:0007169, GO:0007166, GO:0042803, GO:0005515, GO:0005576, GO:0006955, GO:0005886, GO:0005887, GO:0050776, GO:0019901, GO:0051607, GO:0015026, GO:0042288, GO:0002456, GO:0050850, GO:0019882, GO:0042101, GO:0042110, GO:0045065 |
| Gene Ontology Term |
defense response to virus, plasma membrane, protein binding, extracellular region, transmembrane receptor protein tyrosine kinase signaling pathway, external side of plasma membrane, cell surface receptor linked signaling pathway, protein kinase binding, integral to plasma membrane, immune response, protein homodimerization activity, cell surface, regulation of immune response, coreceptor activity, cytotoxic T cell differentiation, MHC class I protein binding, T cell activation, positive regulation of calcium-mediated signaling, antigen processing and presentation, T cell receptor complex, T cell mediated immunity |
| InterPro Term |
Ig_V-set, Ig_sub, Immunoglobulin, Ig-like, Ig_V-set_subgr |
| InterPro ID |
IPR007110, IPR013151, IPR013106, IPR003599, IPR003596 |
| Description |
CD8a molecule [Source:HGNC Symbol;Acc:1706] |
| Ensembl Family Description |
T CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN PRECURSOR T LYMPHOCYTE DIFFERENTIATION ANTIGEN T8/LEU 2 CD8A ANTIGEN |
| Ensembl Family |
ENSFM00500000272758 |
| Ensembl Gene ID |
ENSG00000153563 |
| RefSeq ID |
NP_001139345, NP_001759, NM_001768, NP_741969, NM_001145873, NM_171827 |
| EMBL-Bank ID |
AK124156, AC064848, M27161, M12824, M12828, M26313, M26314, M26315, AK300089, CH471053, AC112696 |
| Ensembl Protein ID |
ENSP00000398868, ENSP00000321631, ENSP00000283635, ENSP00000387314, ENSP00000386559, ENSP00000406978, ENSP00000438371 |
| UniProt Accession |
Q6ZVS2, P01732, B4DT80, B8ZZZ4, E7ETP4 |
| Gene-Disease Assocation |
CD8 DEFICIENCY, FAMILIAL |
| UniGene ID |
Hs.85258 |
| Entrez Gene ID |
925 |
| HGNC Symbol |
CD8A |
| Ensembl Transcript ID |
ENST00000442577, ENST00000352580, ENST00000538832, ENST00000409511, ENST00000283635, ENST00000409781, ENST00000456996 |
| Design Element |
ENST00000442577, 205758_at, 40699_at, Hs.85258.0.S2_3p_at, 74901_at, ENST00000456996, ENST00000538832, M27161_at, ENST00000409511, ENST00000352580, ENST00000409781, ENST00000283635 |
| Search EB-eye |
ENSG00000153563
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