AKT2
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Homo sapiens |
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AKT2 is differentially expressed in 294 experiments: 146 organism parts: bone marrow, blood, ... (144 more);, 194 disease states: normal, Burkitt's lymphoma, ... (192 more);, 91 cell types 385 cell lines 35 compound treatments and 82 other conditions. |
| Orthologs |
ENSCING00000008043
(Ciona intestinalis)
Akt2
(Mus musculus)
Akt2
(Rattus norvegicus)
AKT2
(Bos taurus)
akt2l
(Danio rerio)
akt2
(Danio rerio)
Akt1
(Drosophila melanogaster)
SCH9
(Saccharomyces cerevisiae)
akt2
(Xenopus laevis)
NP_001012340.1
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR017892, IPR001245, IPR017442, IPR000719, IPR000961, IPR001849, IPR020635 |
| Gene Ontology Term |
cytosol, plasma membrane, regulation of JNK cascade, phosphorylation, positive regulation of nitric oxide biosynthetic process, protein binding, vesicle, positive regulation of gene expression, negative regulation of apoptosis, response to osmotic stress, protein tyrosine kinase activity, insulin receptor signaling pathway, soluble fraction, protein kinase B signaling cascade, ATP binding, positive regulation of transcription from RNA polymerase II promoter, transferase activity, transferring phosphorus-containing groups, microsome, protein modification process, nucleus, regulation of cell migration, lamellipodium, nucleotide binding, kinase activity, protein serine/threonine kinase activity, nucleoplasm, signal transduction, negative regulation of caspase activity, protein kinase activity, mitochondrion, negative regulation of RNA splicing, positive regulation of peptidyl-serine phosphorylation, cellular response to insulin stimulus, fat cell differentiation, positive regulation of cell migration, cellular response to chemical stimulus, negative regulation of plasma membrane long-chain fatty acid transport, protein kinase C binding, positive regulation of glycogen biosynthetic process, insulin-responsive compartment, positive regulation of positive chemotaxis, mammary gland epithelial cell differentiation, response to insulin stimulus, positive regulation of glucose import, positive regulation of signal transduction, response to muscle activity, cellular response to hormone stimulus, positive regulation of fatty acid beta-oxidation, positive regulation of sodium ion transport, positive regulation of glucose metabolic process, protein phosphorylation, positive regulation of protein phosphorylation, regulation of cell cycle arrest, positive regulation of cell motility |
| Gene Ontology ID |
GO:0010628, GO:0008286, GO:0007165, GO:0016310, GO:0016301, GO:0031982, GO:0016772, GO:0004713, GO:0005625, GO:0005524, GO:0005515, GO:0005739, GO:0005634, GO:0005654, GO:0005886, GO:0005829, GO:0005792, GO:0006970, GO:0004672, GO:0004674, GO:0046328, GO:0043066, GO:0001934, GO:0043154, GO:0006468, GO:0006464, GO:0000166, GO:0045944, GO:0043491, GO:0030027, GO:0030334, GO:0045429, GO:0033119, GO:0010748, GO:0010765, GO:0009967, GO:0060644, GO:0046326, GO:0032593, GO:0005080, GO:0045725, GO:0032870, GO:0032869, GO:0032868, GO:0014850, GO:0070887, GO:0045444, GO:0030335, GO:0033138, GO:0032000, GO:0050927, GO:0010907, GO:0071156, GO:2000147 |
| Ensembl Family |
ENSFM00520000517810 |
| InterPro Term |
Pkinase_C, AGC-kinase_C, Prot_kinase_cat_dom, Pleckstrin_homology, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family Description |
RAC SERINE/THREONINE KINASE EC_2.7.11.1 KINASE AKT KINASE B PKB RAC PK |
| HGNC Symbol |
AKT2 |
| EMBL-Bank ID |
AC118344, AK055779, BC063421, AK314619, AK294453, BC032709, BC120995, BC120994, M95936, M77198, AY708392, AK304209 |
| Ensembl Gene ID |
ENSG00000105221 |
| Ensembl Protein ID |
ENSP00000403890, ENSP00000403842, ENSP00000309428, ENSP00000396968, ENSP00000407999, ENSP00000351095, ENSP00000396532, ENSP00000392458, ENSP00000375720, ENSP00000375719, ENSP00000375891, ENSP00000375892, ENSP00000399532, ENSP00000404083, ENSP00000441591 |
| UniGene ID |
Hs.631535, Hs.712583 |
| RefSeq ID |
NM_001626, NP_001617, NM_001243027, NM_001243028, NP_001229956, NP_001229957 |
| UniProt Accession |
C9J258, Q0VAN0, A8MX96, C9JC83, C9JIJ1, C9JIF6, C9JHS6, C9K000, Q6P4H3, P31751, B4DG79, B3KP61, Q05BV0, E7EVP8, B7Z8Z9 |
| Description |
v-akt murine thymoma viral oncogene homolog 2 [Source:HGNC Symbol;Acc:392] |
| Entrez Gene ID |
208 |
| Ensembl Transcript ID |
ENST00000480878, ENST00000452077, ENST00000487537, ENST00000391844, ENST00000391845, ENST00000476266, ENST00000476247, ENST00000358335, ENST00000416994, ENST00000424901, ENST00000311278, ENST00000497948, ENST00000492463, ENST00000427375, ENST00000486647, ENST00000486368, ENST00000416362, ENST00000537834, ENST00000489375, ENST00000392038, ENST00000392037, ENST00000483166, ENST00000498350, ENST00000456441, ENST00000491778, ENST00000423127, ENST00000496089, ENST00000441941 |
| Gene-Disease Assocation |
DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM |
| Design Element |
g337490_3p_a_at, Hs2.406970.1.S1_3p_at, 2023_g_at, ENST00000391844, ENST00000391845, ENST00000486368, 87856_r_at, ENST00000486647, Hs.98325.0.A1_3p_at, 225471_s_at, ENST00000537834, 57350_at, ENST00000456441, ENST00000489375, 75878_at, ENST00000498350, ENST00000424901, 211453_s_at, ENST00000483166, ENST00000476247, ENST00000427375, Hs2.406970.1.S1_3p_x_at, 236664_at, ENST00000492463, ENST00000491778, 87854_s_at, ENST00000358335, ENST00000416994, Hs.182278.5.S1_3p_at, ENST00000423127, ENST00000480878, 1560689_3p_s_at, Hs.182278.4.S1_3p_a_at, ENST00000311278, ENST00000416362, 40972_at, ENST00000392038, ENST00000392037, ENST00000496089, M95936_s_at, Hs.326445.0.S1_3p_a_at, ENST00000452077, 87858_r_at, ENST00000476266, ENST00000497948, 203809_s_at, ENST00000487537, ENST00000441941, 1560689_s_at, 226156_at, 78734_s_at |
| Search EB-eye |
ENSG00000105221
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