CBLB
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Homo sapiens |
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CBLB is differentially expressed in 349 experiments: 161 organism parts: bone marrow, mammary gland, ... (159 more);, 225 disease states: normal, prostate carcinoma, ... (223 more);, 117 cell types 425 cell lines 49 compound treatments and 78 other conditions. |
| Synonyms |
RNF56, Cbl-b |
| Orthologs |
ENSCING00000002655
(Ciona intestinalis)
Cblb
(Rattus norvegicus)
CBLB
(Gallus gallus)
cblb
(Danio rerio)
CBLB
(Bos taurus)
Cblb
(Mus musculus)
Cbl
(Drosophila melanogaster)
CBLB
(Xenopus laevis)
CBLB
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
ligase activity, protein binding, cytoplasm, intracellular, membrane raft, NLS-bearing substrate import into nucleus, signal transducer activity, cell surface receptor linked signaling pathway, protein kinase binding, nucleus, response to hormone stimulus, ubiquitin-protein ligase activity, immune response, response to gravity, signal transduction, calcium ion binding, zinc ion binding, positive regulation of protein catabolic process, T cell activation, negative regulation of T cell receptor signaling pathway, phosphotyrosine binding, negative regulation of alpha-beta T cell proliferation, positive regulation of T cell anergy, intracellular signal transduction, regulation of signaling |
| InterPro ID |
IPR018957, IPR000449, IPR001841, IPR014742, IPR014741, IPR015940, IPR003153 |
| Gene Ontology ID |
GO:0008270, GO:0007166, GO:0007165, GO:0009629, GO:0009725, GO:0016874, GO:0005622, GO:0005509, GO:0005515, GO:0004842, GO:0004871, GO:0006955, GO:0005737, GO:0005634, GO:0006607, GO:0019901, GO:0045121, GO:0002669, GO:0050860, GO:0045732, GO:0001784, GO:0042110, GO:0046642, GO:0035556, GO:0023051 |
| InterPro Term |
UBA/transl_elong_EF1B_N_euk, UBA/transl_elong_EF1B_N, Znf_RING, Znf_C3HC4_RING-type, Adaptor_Cbl_SH2-like, Adaptor_Cbl_EF_hand-like, Adaptor_Cbl_N_hlx |
| Ensembl Family |
ENSFM00250000001327 |
| Ensembl Family Description |
E3 UBIQUITIN LIGASE CBL EC_6.3.2.- CASITAS B LINEAGE LYMPHOMA PROTO ONCOGENE CBL SIGNAL TRANSDUCTION CBL |
| Description |
Cas-Br-M (murine) ecotropic retroviral transforming sequence b [Source:HGNC Symbol;Acc:1542] |
| Ensembl Protein ID |
ENSP00000393906, ENSP00000409750, ENSP00000377598, ENSP00000377595, ENSP00000400949, ENSP00000264122, ENSP00000384938, ENSP00000384816, ENSP00000384170, ENSP00000446116 |
| EMBL-Bank ID |
AB075490, CR749655, BX537484, U26710, U26712, U26711, BC032851, AC016138, AK292792, CH471052, AC126185, DQ349203, AC112485 |
| RefSeq ID |
NM_170662, NP_733762 |
| UniProt Accession |
Q13191, B5MC15, A8K9S7, C9JRB3, Q68CY2, C9JU85, E7ENW2, E9PHA9, F5H4J9 |
| UniGene ID |
Hs.622985, Hs.430589 |
| HGNC Symbol |
CBLB |
| Ensembl Gene ID |
ENSG00000114423 |
| Entrez Gene ID |
868 |
| Ensembl Transcript ID |
ENST00000403724, ENST00000476370, ENST00000438603, ENST00000447441, ENST00000545639, ENST00000443752, ENST00000407712, ENST00000394027, ENST00000394030, ENST00000264122, ENST00000405772 |
| Design Element |
56250_r_at, 62255_at, ENST00000476370, ENST00000545639, 227900_at, ENST00000394027, g862406_3p_at, 61071_at, 208348_s_at, 35632_at, ENST00000405772, U26712_at, 56247_i_at, g4757919_3p_a_at, ENST00000407712, ENST00000264122, Hs.144139.0.A1_3p_at, 209682_at, 515_s_at, ENST00000438603, ENST00000447441, 514_at, U26710_at, ENST00000403724, 79308_at, ENST00000394030, ENST00000443752 |
| Search EB-eye |
ENSG00000114423
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