PDK1
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Homo sapiens |
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PDK1 is differentially expressed in 282 experiments: 125 organism parts: adipose tissue, kidney, ... (123 more);, 152 disease states: normal, acute myeloid leukemia, ... (150 more);, 87 cell types 394 cell lines 34 compound treatments and 77 other conditions. |
| Orthologs |
PDK1
(Gallus gallus)
PDK1
(Bos taurus)
Pdk1
(Rattus norvegicus)
PDK1
(Danio rerio)
ENSCING00000001943
(Ciona intestinalis)
Pdk1
(Mus musculus)
PKP2
(Saccharomyces cerevisiae)
Pdk
(Drosophila melanogaster)
pdk1
(Xenopus laevis)
PDK1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
glucose metabolic process, mitochondrial matrix, pyruvate dehydrogenase complex, ATP binding, peptidyl-histidine phosphorylation, small GTPase mediated signal transduction, cell surface receptor linked signaling pathway, protein heterodimerization activity, protein histidine kinase activity, two-component sensor activity, nucleotide binding, kinase activity, carbohydrate metabolic process, transferase activity, protein homodimerization activity, signal transduction, protein kinase activity, pyruvate metabolic process, pyruvate dehydrogenase (acetyl-transferring) kinase activity, mitochondrion, protein complex binding, protein phosphorylation, regulation of acetyl-CoA biosynthetic process from pyruvate |
| Gene Ontology ID |
GO:0007166, GO:0007165, GO:0007264, GO:0016301, GO:0005975, GO:0016740, GO:0004740, GO:0042803, GO:0005524, GO:0005739, GO:0005759, GO:0004673, GO:0004672, GO:0006468, GO:0000166, GO:0018106, GO:0000155, GO:0046982, GO:0006090, GO:0006006, GO:0045254, GO:0032403, GO:0010510 |
| InterPro ID |
IPR005467, IPR003594, IPR018955 |
| Ensembl Family Description |
[PYRUVATE DEHYDROGENASE [LIPOAMIDE]] KINASE ISOZYME MITOCHONDRIAL PRECURSOR EC_2.7.11.2 PYRUVATE DEHYDROGENASE KINASE |
| Ensembl Family |
ENSFM00500000269765 |
| InterPro Term |
ATPase-like_ATP-bd, Sig_transdc_His_kinase_core, BCDHK/PDK_N |
| UniProt Accession |
Q15118, Q53R49, C9IYB4, C9JKT3, B7Z7N6, B7Z207, E9PD65, F8WEJ6, F8WC75 |
| HGNC Symbol |
PDK1 |
| EMBL-Bank ID |
BC039158, AC018712, AC093818, CH471058, AK312700, AK294194, AK302321, L42450 |
| Description |
pyruvate dehydrogenase kinase, isozyme 1 [Source:HGNC Symbol;Acc:8809] |
| UniGene ID |
Hs.470633 |
| Ensembl Protein ID |
ENSP00000413629, ENSP00000399160, ENSP00000388366, ENSP00000386985, ENSP00000376352, ENSP00000399558, ENSP00000406608, ENSP00000282077, ENSP00000437502, ENSP00000438567 |
| Ensembl Gene ID |
ENSG00000152256 |
| RefSeq ID |
NP_002601, NM_002610 |
| Entrez Gene ID |
5163 |
| Ensembl Transcript ID |
ENST00000431718, ENST00000436490, ENST00000543905, ENST00000416991, ENST00000282077, ENST00000544863, ENST00000443353, ENST00000392571, ENST00000439519, ENST00000466437, ENST00000410055 |
| Design Element |
ENST00000416991, 48193_at, 226452_at, Hs.61712.1.S1_3p_at, ENST00000443353, ENST00000282077, ENST00000436490, g7108358_3p_at, ENST00000410055, ENST00000544863, ENST00000392571, ENST00000439519, L42450_at, ENST00000466437, ENST00000543905, 206686_at, ENST00000431718, 36386_at, 53964_at |
| Search EB-eye |
ENSG00000152256
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