SOX17
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Homo sapiens |
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SOX17 is differentially expressed in 156 experiments: 120 organism parts: lung, uterus, ... (118 more);, 138 disease states: normal, healthy, ... (136 more);, 40 cell types 129 cell lines 16 compound treatments and 66 other conditions. |
| Orthologs |
SOX17
(Bos taurus)
Sox17
(Mus musculus)
sox17
(Danio rerio)
Q4H2R8_CIOIN
(Ciona intestinalis)
Sox17
(Rattus norvegicus)
Sox15
(Drosophila melanogaster)
sox17a
(Xenopus laevis)
sox17b.2
(Xenopus laevis)
sox17b.1
(Xenopus laevis)
SOX17
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
angiogenesis, negative regulation of cell growth, DNA binding, protein stabilization, protein binding, regulation of transcription, DNA-dependent, beta-catenin binding, embryonic heart tube development, stem cell differentiation, transcription, DNA-dependent, positive regulation of gene expression, endoderm formation, embryonic foregut morphogenesis, spermatogenesis, negative regulation of Wnt receptor signaling pathway, transcription factor binding, sequence-specific DNA binding, endoderm development, positive regulation of transcription from RNA polymerase II promoter, transcription coactivator activity, nucleus, canonical Wnt receptor signaling pathway, regulation of cell differentiation, regulation of embryonic development, transcription factor complex, endodermal cell fate determination, negative regulation of transcription from RNA polymerase II promoter, gastrulation, positive regulation of transcription, DNA-dependent, embryonic organ development, outflow tract morphogenesis, embryonic heart tube morphogenesis, positive regulation of skeletal muscle tissue development, positive regulation of protein catabolic process, cell migration involved in gastrulation, endocardium formation, endodermal digestive tract morphogenesis, cardiac cell fate determination, protein destabilization, gall bladder development, vasculogenesis, heart formation, positive regulation of cell differentiation, negative regulation of mesodermal cell fate specification, stem cell fate specification, regulation of stem cell division, endocardial cell differentiation, renal system development, negative regulation of canonical Wnt receptor signaling pathway, heart looping, rostrocaudal neural tube patterning, regulation of mesodermal cell fate specification, sequence-specific DNA binding transcription factor activity, negative regulation of Wnt receptor signaling pathway involved in heart development, signal transduction involved in regulation of gene expression, transcription regulatory region DNA binding, common bile duct development, regulation of stem cell proliferation, cardiogenic plate morphogenesis, regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification, regulation of cardiac cell fate specification, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity, inner cell mass cellular morphogenesis |
| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0010628, GO:0003713, GO:0003700, GO:0003705, GO:0008013, GO:0060070, GO:0007283, GO:0007369, GO:0007492, GO:0007493, GO:0048863, GO:0048617, GO:0005515, GO:0005634, GO:0005667, GO:0050821, GO:0000122, GO:0006355, GO:0006351, GO:0001706, GO:0045595, GO:0045944, GO:0045995, GO:0001525, GO:0043565, GO:0045893, GO:0030178, GO:0030308, GO:0035050, GO:0072001, GO:0060214, GO:0048866, GO:0048643, GO:0048568, GO:0042662, GO:0003151, GO:0003143, GO:2000035, GO:0061031, GO:0061010, GO:0061009, GO:0090090, GO:0001947, GO:0045732, GO:0031648, GO:0045597, GO:0042074, GO:0001570, GO:0044212, GO:0060956, GO:0060914, GO:0060913, GO:0021903, GO:0042661, GO:0003308, GO:0023019, GO:0072091, GO:0003142, GO:0060807, GO:2000043, GO:0001828 |
| InterPro ID |
IPR000910, IPR021934 |
| InterPro Term |
HMG_HMG1/HMG2, DUF3547 |
| Ensembl Family |
ENSFM00560000771205 |
| Ensembl Family Description |
TRANSCRIPTION FACTOR SOX 17 BETA SRY SEX DETERMINING REGION Y BOX 17 BETA |
| Entrez Gene ID |
64321 |
| RefSeq ID |
NP_071899, NM_022454 |
| UniProt Accession |
Q9H6I2, Q2T9L5, Q2NKK5 |
| Description |
SRY (sex determining region Y)-box 17 [Source:HGNC Symbol;Acc:18122] |
| Ensembl Protein ID |
ENSP00000297316 |
| EMBL-Bank ID |
AB073988, BC030209, BC111365, BC111770, AK025905 |
| Ensembl Gene ID |
ENSG00000164736 |
| HGNC Symbol |
SOX17 |
| UniGene ID |
Hs.605567, Hs.607058, Hs.98367 |
| Ensembl Transcript ID |
ENST00000297316 |
| Gene-Disease Assocation |
VESICOURETERAL REFLUX 3; VUR3 |
| Design Element |
63045_at, 55547_at, ENST00000297316, 219993_at, g11967990_3p_at, 61415_at, 230943_at, Hs.98367.0.A1_3p_at |
| Search EB-eye |
ENSG00000164736
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