pgrn-1
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Caenorhabditis elegans |
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pgrn-1 is differentially expressed in 4 experiments: 4 genotypes: mex-3(zu155)+skn-1(RNAi), rde-4(ne337), ... (2 more);, 2 infections: E. coli OP50, Yersinia pestis;, 3 strain or lines |
| Orthologs |
ENSCING00000012906
(Ciona intestinalis)
grna
(Danio rerio)
Grn
(Mus musculus)
GRN
(Homo sapiens)
GRN
(Bos taurus)
grnb
(Danio rerio)
Grn
(Rattus norvegicus)
grn2
(Danio rerio)
grn1
(Danio rerio)
grn
(Xenopus laevis)
(Compare orthologs)
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| InterPro Term |
Granulin |
| InterPro ID |
IPR000118 |
| Ensembl Family |
ENSFM00500000287139 |
| Ensembl Protein ID |
T22H2.6b, T22H2.6a |
| Ensembl Family Description |
PARTIALLY CONFIRMED BY TRANSCRIPT EVIDENCE |
| Description |
pgrn-1 encodes an ortholog of human progranulin (OMIM:138945, mutated in ubiquitin-positive frontotemporal dementia). granulin participates in various developmental events (cavitation in preimplantation embryos and male-specific brain differentiation), promotes granulation and neovascularization during wound healing, and is strongly expressed in various tumors. [Source: WormBase] |
| Ensembl Gene ID |
T22H2.6 |
| Entrez Gene ID |
173054 |
| UniProt Accession |
Q9U362, Q7JKP2 |
| RefSeq ID |
NP_492981, NP_492982, NM_060581, NM_060580 |
| EMBL-Bank ID |
Z81595 |
| Ensembl Transcript ID |
T22H2.6a, T22H2.6b |
| UniGene ID |
Cel.16709 |
| Design Element |
180962_s_at, 194228_x_at, 172800_x_at |
| Search EB-eye |
T22H2.6
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