Gene Expression Atlas home | about the project | faq | feedback | blog | das | api | help
Pdgfrb
REST API REST API
Rattus norvegicus
Pdgfrb is differentially expressed in 65 experiments: 42 organism parts: hippocampus, frontal cortex, ... (40 more);, 7 disease states: normal, BDL 7 days, ... (5 more);, 9 cell types 2 cell lines 8 compound treatments and 15 other conditions.
Orthologs PDGFRB (Homo sapiens)   Pdgfrb (Mus musculus)   pdgfrb2 (Danio rerio)   F1N868_CHICK (Gallus gallus)   Pvr (Drosophila melanogaster)   PDGFRB (Xenopus laevis)   (Compare orthologs)
InterPro Term Ig_V-set, Ig_sub, Immunoglobulin, Se/Thr_prot_kinase-like_dom, Kinase-like_dom, Ser/Thr_prot_kinase_dom, Tyr_prot_kinase_AS, Prot_kinase_cat_dom, Ig-like, Ig_sub2, Tyr_Pkinase_cat_dom, Tyr_prot_kinase_VEGFR_rcpt_N, Protein_kinase_ATP_BS, Ser-Thr/Tyr-Pkinase, Tyr_prot_kinase_CSF1/PDGF_rcpt, Tyr_prot_kinase_rcpt_3_CS, Ig_I-set, Ig_V-set_subgr
Gene Ontology Term response to hydrogen peroxide, plasma membrane, phosphorylation, protein binding, cytoplasm, response to toxin, wound healing, positive regulation of cell proliferation, membrane, peptidyl-tyrosine phosphorylation, protein tyrosine kinase activity, transforming growth factor beta receptor signaling pathway, receptor binding, positive regulation of MAP kinase activity, transmembrane receptor protein tyrosine kinase signaling pathway, glycosaminoglycan biosynthetic process, signal transducer activity, hemopoiesis, ATP binding, transferase activity, transferring phosphorus-containing groups, integral to plasma membrane, nucleus, receptor activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, transmembrane receptor protein tyrosine kinase activity, cellular_component, apical plasma membrane, integral to membrane, tissue homeostasis, regulation of actin cytoskeleton organization, nitrogen compound metabolic process, signal transduction, protein kinase activity, intracellular protein kinase cascade, metanephric comma-shaped body morphogenesis, cell chemotaxis, response to fluid shear stress, positive regulation of smooth muscle cell migration, in utero embryonic development, regulation of peptidyl-tyrosine phosphorylation, platelet-derived growth factor beta-receptor activity, kidney development, positive regulation of ERK1 and ERK2 cascade, positive regulation of collagen biosynthetic process, adrenal gland development, metanephric S-shaped body morphogenesis, inner ear development, platelet-derived growth factor receptor signaling pathway, positive regulation of cell migration, positive regulation of anti-apoptosis, response to estrogen stimulus, cardiac myofibril assembly, positive regulation of chemotaxis, response to retinoic acid, smooth muscle tissue development, response to lipid, response to estradiol stimulus, growth factor binding, platelet-derived growth factor binding, skeletal system morphogenesis, positive regulation of smooth muscle cell proliferation, response to hyperoxia, platelet-derived growth factor receptor binding, positive regulation of mitosis, protein autophosphorylation, protein phosphorylation, retina vasculature development in camera-type eye, positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, metanephric glomerular mesangial cell proliferation involved in metanephros development, platelet-derived growth factor receptor-beta signaling pathway, response to organic cyclic compound, positive regulation of reactive oxygen species metabolic process, metanephric glomerular capillary formation, positive regulation of calcium ion import, metanephric mesenchyme development, phosphatidylinositol 3-kinase binding, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of DNA biosynthetic process, aorta morphogenesis, smooth muscle cell chemotaxis, metanephric glomerulus morphogenesis, metanephric mesenchymal cell migration, vascular endothelial growth factor-activated receptor activity, platelet-derived growth factor-activated receptor activity
UniProt Accession Q05030, Q003I6
Search EB-eye ENSRNOG00000018461
Show more properties
Experimental Factors
Organism part

studied in E-GEOD-15184, E-GEOD-19830, E-GEOD-20388, E-GEOD-2354, E-AFMX-7, ... (16 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-20037

Factor Value U/D Experiments
Rat-1 fibroblast cell line 15.19
1
1
E-GEOD-20037
Rat-1 fibroblast cell line TGR
1
1
E-GEOD-20037


Cell type

studied in E-MEXP-31, E-GEOD-1567, E-TABM-130, E-GEOD-2032

Factor Value U/D Experiments
Sertoli cell
2
2
E-TABM-130, E-MEXP-31
alveolar epithelial type I
1
E-GEOD-1567
spermatid
1
1
E-TABM-130
fibroblast
1
E-GEOD-2032
myoctye
1
E-GEOD-2032
total testis
1
E-MEXP-31
3 more value(s).


Disease state

studied in E-MEXP-874, E-GEOD-1872, E-GEOD-1843, E-GEOD-464, E-MEXP-2583 ... (5 experiments)

Factor Value U/D Experiments
normal
1
2
E-GEOD-1843, E-MEXP-874, E-GEOD-1872
experimental colitis
2
1
E-MEXP-874
BDL 7 days
1
1
E-MEXP-2583
cirrhosis
1
E-GEOD-1843
breast carcinoma
1
E-GEOD-1872
Sham
1
1
E-MEXP-2583
1 more value(s).


Compound treatment

studied in E-GEOD-5509, E-MEXP-1169, E-GEOD-2331, E-GEOD-2303, E-MEXP-782, ... (6 experiments)

Factor Value U/D Experiments
sulphated cholecystokinin-8
1
E-MEXP-1169
alpha-naphthylisothiocyanate
1
1
E-GEOD-5509
glucosamine
1
1
E-GEOD-6119
interleukin 1 beta
1
1
E-GEOD-6119
none
1
1
E-MEXP-782, E-GEOD-2331
clofibrate
1
E-GEOD-2303
2 more value(s).


Clinical treatment

studied in E-GEOD-7002, E-MTAB-104

Factor Value U/D Experiments
instillation
1
1
E-GEOD-7002
inhalation
1
1
E-GEOD-7002
no implantation
1
E-MTAB-104


Cohort
studied in E-GEOD-20388

compound_treatment_design
studied in E-TABM-12

Developmental stage
studied in E-GEOD-4236, E-GEOD-20245

Diet
studied in E-GEOD-21681

Genetic modification
studied in E-GEOD-6428

Genotype
studied in E-MTAB-322, E-GEOD-20037, E-GEOD-20214

Growth condition
studied in E-MEXP-2863, E-GEOD-7501, E-MEXP-532

Material type
studied in E-GEOD-4192, E-MEXP-2527

Phenotype
studied in E-MIMR-541, E-GEOD-2275

Protocol type
studied in E-MEXP-532, E-MEXP-1565

Replicate
studied in E-GEOD-4192

Sampling time point
studied in E-MEXP-1565

Strain or line
studied in E-MTAB-322, E-TABM-457, E-MTAB-323

Treatment
studied in E-GEOD-16981, E-GEOD-19909

Processing time: 0.113 secs.
 
Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM