Nbn
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Rattus norvegicus |
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Nbn is differentially expressed in 42 experiments: 32 organism parts: 0 % liver / 0 % brain / 100 % lung, 0 % liver / 100 % brain / 0 % lung, ... (30 more);, 2 disease states: breast carcinoma, normal;, 2 cell types 5 compound treatments 2 clinical treatments and 10 other conditions. |
| Synonyms |
Nbs1, MGC93174 |
| Orthologs |
NBN
(Gallus gallus)
Nbn
(Mus musculus)
ENSCING00000002421
(Ciona intestinalis)
nbn
(Danio rerio)
NBN
(Homo sapiens)
nbs
(Drosophila melanogaster)
nbn
(Xenopus laevis)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003684, GO:0003674, GO:0008283, GO:0008284, GO:0007049, GO:0007131, GO:0007126, GO:0004003, GO:0042493, GO:0000077, GO:0000075, GO:0005622, GO:0005515, GO:0047485, GO:0006915, GO:0005730, GO:0005694, GO:0005634, GO:0005657, GO:0030870, GO:0000723, GO:0032508, GO:0000784, GO:0006302, GO:0007095, GO:0031954, GO:0042405, GO:0048145, GO:0050885, GO:0001701, GO:0045665, GO:0001832, GO:0031576, GO:0031575, GO:0033674, GO:0045190 |
| Gene Ontology Term |
telomere maintenance, reciprocal meiotic recombination, DNA damage checkpoint, protein binding, apoptosis, cell proliferation, damaged DNA binding, Mre11 complex, intracellular, meiosis, positive regulation of cell proliferation, protein N-terminus binding, replication fork, double-strand break repair, transcription factor binding, DNA duplex unwinding, nuclear chromosome, telomeric region, molecular_function, cell cycle, nucleus, ATP-dependent DNA helicase activity, response to drug, chromosome, cell cycle checkpoint, nucleolus, nuclear inclusion body, regulation of fibroblast proliferation, in utero embryonic development, blastocyst growth, mitotic cell cycle G2/M transition DNA damage checkpoint, neuromuscular process controlling balance, negative regulation of neuron differentiation, G2/M transition checkpoint, isotype switching, positive regulation of kinase activity, positive regulation of protein autophosphorylation, mitotic cell cycle G1/S transition checkpoint |
| InterPro ID |
IPR016592, IPR001357, IPR000253, IPR008984, IPR013908 |
| InterPro Term |
SMAD_FHA_domain, Nibrin_met, FHA_dom, BRCT, DNA-repair_Nbs1_C |
| Ensembl Protein ID |
ENSRNOP00000012377 |
| EMBL-Bank ID |
AF218575, BC085700 |
| RefSeq ID |
NP_620228, NM_138873 |
| Ensembl Gene ID |
ENSRNOG00000008580 |
| RGD Symbol |
Nbn |
| Entrez Gene ID |
85482 |
| Ensembl Family |
ENSFM00250000006409 |
| Ensembl Family Description |
NIBRIN NIJMEGEN BREAKAGE SYNDROME 1 |
| UniProt Accession |
Q9JIL9 |
| RGD ID |
621420 |
| UniGene ID |
Rn.25214 |
| Ensembl Transcript ID |
ENSRNOT00000012377 |
| Description |
Nibrin [Source:UniProtKB/Swiss-Prot;Acc:Q9JIL9] |
| Design Element |
6735257, 6547220, 5665202, rc_AI137049_at, 6217964, 6002681, 5827214, 5829857, 6694383, 1387977_at, 6615817, 5755466, 6612081, 6300153, 5684394, 6479668, ENSRNOT00000012377, 6088238, 5762658, 6681304, 6554762, 5934876, 6340735, 6154399 |
| Search EB-eye |
ENSRNOG00000008580
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